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Cat. No.	Product Name	Target	Signaling Pathways
T9700	EZH2-IN-2	Histone Methyltransferase	Chromatin/Epigenetic
	EZH2-IN-2 是一种 EZH2 抑制剂，IC50 值为 64 nM。EZH2-IN-2 可用于研究与 EZH2 活性相关的癌症或癌前病变。
T40323	EZH2-IN-6 EZH2-IN-6
	EZH2-IN-6 is an EZH2 inhibitor with enhanced antitumor activity.
T38827	EZH2-IN-5 EZH2-IN-5
	EZH2-IN-5 is a highly effective inhibitor of EZH2, displaying remarkable potency against both wild-type and mutant Tyr641 EZH2, with IC50 values of 1.52 nM and 4.07 nM, respectively.
T39497	EZH2-IN-4 EZH2-IN-4
	EZH2-IN-4 is a highly potent EZH2 inhibitor that can be taken orally. It exhibits inhibitory effects against wild type (WT) 5-membered (5-mer) EZH2 and mutant 5-mer EZH2, with IC 50 values of 0.923 nM and 2.65 nM, respectively. Moreover, EZH2-IN-4 has demonstrated significant anti-cancer activity.
T40310	PARP/EZH2-IN-1 PARP/EZH2-IN-1
	PARP/EZH2-IN-1 is a novel compound that functions as a dual inhibitor for both PARP (IC50 6.87 nM) and EZH2 (IC50 36.51 nM), showing promising potential for the treatment of triple-negative breast cancer with wild-type BRCA.
T25400	EZH2-IN-3 EZH2 inhibitor 3,EZH2-inhibitor-3
	EZH2-IN-3 is an inhibitor of EZH2 and EZH1 with selective impact on diffuse large B cell lymphoma cell growth.
T67883	EZH2-IN-15 SHR2554	Histone Methyltransferase	Chromatin/Epigenetic
	EZH2-IN-15 是zeste 2组蛋白修饰增强子(EZH2)的特异性抑制剂。EZH2在许多人类癌症中异常过表达，通过调节Treg 活性来控制适应性反应。肿瘤内EZH2的表达也被证明可以控制先天免疫
T74675	MS8815
	MS8815 是 zeste 同源物2(EZH2)PROTAC 降解剂，具有选择性。MS8815 对 EZH2有抑制活性，IC50值为 8.6 nM。MS8815 可用于三阴性乳腺癌 (TNBC) 研究。

化合物

Cat.No: T9700

Target: Histone Methyltransferase

Cat.No: T40323

Synonym: EZH2-IN-6

Cat.No: T38827

Synonym: EZH2-IN-5

Cat.No: T39497

Synonym: EZH2-IN-4

PARP/EZH2-IN-1

Cat.No: T40310

Synonym: PARP/EZH2-IN-1

Cat.No: T25400

Synonym: EZH2 inhibitor 3,EZH2-inhibitor-3

Cat.No: T67883

Synonym: SHR2554

Target: Histone Methyltransferase

Cat.No: T74675

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