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Cat. No.	Product Name	Target	Signaling Pathways
T15189	Thalidomide-O-amido-C4-N3 E3 ligase Ligand-Linker Conjugates 18,Cereblon Ligand-Linker Conjugates 4	Others; Ligand for E3 Ligase	Others; PROTAC
	Thalidomide-O-amido-C4-N3 (Cereblon Ligand-Linker Conjugates 4) 是一种 E3 连接酶配体- linker 偶联物，包含基于 Thalidomide 的 cereblon 配体和 linker。
T17921	(S,R,S)-AHPC-PEG4-N3 VH032-PEG4-N3,VHL Ligand-Linker Conjugates 5,E3 ligase Ligand-Linker Conjugates 4	Others; PROTAC Linker	Others; PROTAC
	(S,R,S)-AHPC-PEG4-N3 (VHL Ligand-Linker Conjugates 5) is a synthesized conjugate that functions as a ligand-linker in E3 ligase-based systems. It is composed of the (S,R,S)-AHPC VHL ligand and a 4-unit PEG linker, both commonly employed in PROTAC technology.
T17325	Pomalidomide-PEG4-C-COOH Cereblon Ligand -Linker Conjugates 1,E3 Ligase Ligand-Linker Conjugates 1	Others; E3 Ligase Ligand-Linker Conjugate	Others; PROTAC
	Pomalidomide-PEG4-C-COOH (E3 Ligase Ligand-Linker Conjugates 1) 包含基于 Pomalidomide 的 cereblon 配体和 4 个单元 PEG linker，是一种合成的 E3 连接酶配体-linker 偶联物。
T7759	Thalidomide-O-amido-C4-NH2 TFA E3 ligase Ligand-Linker Conjugates 19 TFA,Cereblon Ligand-Linker Conjugates 6 TFA	E3 Ligase Ligand-Linker Conjugate	PROTAC
	Thalidomide-O-amido-C4-NH2 TFA (E3 ligase Ligand-Linker Conjugates 19 TFA) 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker，是一种合成的 E3 连接酶配体-linker 偶联物。
T15190L	(S,R,S)-AHPC-PEG4-NH2 VHL Ligand-Linker Conjugates 4,E3 ligase Ligand-Linker Conjugates 7 Free Base,VH032-PEG4-NH2	Others; Ligand for E3 Ligase	Others; PROTAC
	(S,R,S)-AHPC-PEG4-NH2 (VHL Ligand-Linker Conjugates 4) 是一种合成的 E3 连接酶配体-接头偶联物，包含基于 (S,R,S)-AHPC 的 VHL 配体和 4 单元 PEG 接头。
T9387	Pomalidomide 4'-PEG2-azide	E3 Ligase Ligand-Linker Conjugate	PROTAC
	Pomalidomide 4'-PEG2-azide 是由E3 连接酶配体和linker 组成的偶联物，包括基于 Pomalidomide 的 cereblon 配体和linker。
T40030	Thalidomide 4'-ether-alkylC2-amine hydrochloride halidomide-linker 6	E3 Ligase Ligand-Linker Conjugate	PROTAC
	Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) 包含基于 Thalidomide 的 cereblon 配体和 linker，是合成的 E3 连接酶配体-linker 偶联物，可应用于 PROTAC 技术。
T9402	Thalidomide-O-C4-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugate	PROTAC
	Thalidomide-O-C4-NH2 hydrochloride 包含基于 Thalidomide 的 cereblon 配体和 PROTAC 技术中使用的接头，是一种合成的 E3 连接酶配体-接头偶联物。
T18807	Thalidomide-NH-C4-NH-Boc	E3 Ligase Ligand-Linker Conjugate; Ligand for E3 Ligase	PROTAC
	Thalidomide-NH-C4-NH-Boc 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker，是一种合成的 E3 连接酶配体-linker 偶联物。
T9389	Thalidomide-PEG4-Propargyl Thalidomide-O-PEG4-Propargyl	E3 Ligase Ligand-Linker Conjugate	PROTAC
	Thalidomide-PEG4-Propargyl (Thalidomide-O-PEG4-Propargyl) 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker，是一种合成的 E3 连接酶配体-linker 偶联物，。
T17896	cIAP1 Ligand-Linker Conjugates 4 E3 ligase Ligand-Linker Conjugates 42	Others	Others
	cIAP1 Ligand-Linker Conjugates 4 is a chemical compound that comprises an IAP ligand specifically designed for the E3 ubiquitin ligase and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 4, has the potential to be utilized in the development of SNIPERs[1].
T17818	Thalidomide-O-amido-C4-NH2 E3 Ligase Ligand-Linker Conjugates 19,Cereblon Ligand-Linker Conjugates 6	Others	Others
	Thalidomide-O-amido-C4-NH2 (Cereblon Ligand-Linker Conjugates 6) is a synthesized ligand-linker conjugate that combines a Thalidomide-based cereblon ligand with a linker. It functions as an E3 ligase ligand-linker conjugate and finds applications in the synthesis of PROTACs[1].
T17907	Pomalidomide-amido-C4-amido-C6-NH-Boc Cereblon Ligand-Linker Conjugates 21,E3 Ligase Ligand-Linker Conjugates 54	Others	Others
	Pomalidomide-amido-C4-amido-C6-NH-Boc, a synthesized conjugate, is a ligand-linker incorporating the cereblon ligand based on Pomalidomide and a PROTAC technology linker.
T17906	Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc E3 Ligase Ligand-Linker Conjugates 53,Cereblon Ligand-Linker Conjugates 20	Others	Others
	Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc is a novel synthesized conjugate compound functioning as an E3 ligase ligand-linker in PROTAC technology. This compound incorporates a Pomalidomide-derived cereblon ligand, which binds selectively to the E3 ligase cereblon, and a 2-unit PEG linker, which provides stability and flexibility to the conjugate.
T9401	Thalidomide-NH-PEG1-NH2 hydrochloride 4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl	E3 Ligase Ligand-Linker Conjugate	PROTAC
	Thalidomide-NH-PEG1-NH2 hydrochloride (4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl) 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker，是合成的 E3 连接酶配体-linker 偶联物，可用于 PROTAC 的合成。
T15190	(S,R,S)-AHPC-PEG4-NH2 hydrochloride E3 ligase Ligand-Linker Conjugates 7,VH032-PEG4-NH2 hydrochloride,VHL Ligand-Linker Conjugates 4 hydrochloride	Others	Others
	(S, R, S)-AHPC-PEG4-NH2 hydrochloride is a chemically synthesized conjugate consisting of an E3 ligase ligand-linker, incorporating the VHL ligand based on (S, R, S)-AHPC, and a 4-unit PEG linker, which are specifically designed for use in PROTAC technology.
T9382	Thalidomide-NH-C2-PEG3-OH H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]-	E3 Ligase Ligand-Linker Conjugate	PROTAC
	Thalidomide-NH-C2-PEG3-OH (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]-) 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker，是 E3 连接酶配体-linker 偶联物，可用于合成 PROTAC BCL-XL 降解剂 XZ739。
T17878	Lenalidomide-C4-NH2 hydrochloride Cereblon ligand 1 hydrochloride,E3 ligase Ligand-Linker Conjugates 32 hydrochloride	Others	Others
	Lenalidomide-C4-NH2 hydrochloride is a Cereblon ligand derived from Lenalidomide. It serves as a recruiting agent for the CRBN protein. The compound, known as PROTAC (Compound 24), can be formed by linking Lenalidomide-C4-NH2 hydrochloride to the ligand for the protein. It exhibits inhibitory effects with IC50s of 0.98 nM and 13.7 nM against the growth of RS4;11 and MOLM-13 acute leukemia cell lines, respectively[1].
T40031	Thalidomide-O-C6-NH2 hydrochloride 4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride,萨力多胺-O-C6-氨基盐酸盐	E3 Ligase Ligand-Linker Conjugate	PROTAC
	Thalidomide-O-C6-NH2 hydrochloride (4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride) 是一种合成的E3 连接酶配体 -linker 偶联物，用于 PROTAC dTAG-13 的合成。其中 dTAG-13 是一种 FKBP12F36V 和 BET 的降解剂。
T17875	Pomalidomide-C2-NH2 Cereblon Ligand-Linker Conjugates 15,4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione	Others; Ligand for E3 Ligase	Others; PROTAC
	Pomalidomide-C2-NH2 (4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione) 包含基于 Pomalidomide 的 cereblon 配体和 1 个 linker，是一种合成的 E3 连接酶配体-linker 偶联物，。
T18822	Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride	Others; Ligand for E3 Ligase	Others; PROTAC
	Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride 是一种合成的 E3 连接酶配体- linker 偶联物，包含基于 Thalidomide 的 cereblon 配体和 linker 。
T17916	Pomalidomide-PEG4-C2-NH2 Cereblon Ligand-Linker Conjugates 8,E3 Ligase Ligand-Linker Conjugates 22	Others; Ligand for E3 Ligase	Others; PROTAC
	Pomalidomide-PEG4-C2-NH2 (E3 Ligase Ligand-Linker Conjugates 22) 是一种合成的 E3 连接酶配体- linker 偶联物，用于 PROTAC 技术中。

化合物

Thalidomide-O-amido-C4-N3

Cat.No: T15189

Synonym: E3 ligase Ligand-Linker Conjugates 18,Cereblon Ligand-Linker Conjugates 4

Target: Others, Ligand for E3 Ligase

(S,R,S)-AHPC-PEG4-N3

Cat.No: T17921

Synonym: VH032-PEG4-N3,VHL Ligand-Linker Conjugates 5,E3 ligase Ligand-Linker Conjugates 4

Target: Others, PROTAC Linker

Pomalidomide-PEG4-C-COOH

Cat.No: T17325

Synonym: Cereblon Ligand -Linker Conjugates 1,E3 Ligase Ligand-Linker Conjugates 1

Target: Others, E3 Ligase Ligand-Linker Conjugate

Thalidomide-O-amido-C4-NH2 TFA

Cat.No: T7759

Synonym: E3 ligase Ligand-Linker Conjugates 19 TFA,Cereblon Ligand-Linker Conjugates 6 TFA

Target: E3 Ligase Ligand-Linker Conjugate

(S,R,S)-AHPC-PEG4-NH2

Cat.No: T15190L

Synonym: VHL Ligand-Linker Conjugates 4,E3 ligase Ligand-Linker Conjugates 7 Free Base,VH032-PEG4-NH2

Target: Others, Ligand for E3 Ligase

Pomalidomide 4'-PEG2-azide

Cat.No: T9387

Target: E3 Ligase Ligand-Linker Conjugate

Thalidomide 4'-ether-alkylC2-amine hydrochloride

Cat.No: T40030

Synonym: halidomide-linker 6

Target: E3 Ligase Ligand-Linker Conjugate

Thalidomide-O-C4-NH2 hydrochloride

Cat.No: T9402

Target: E3 Ligase Ligand-Linker Conjugate

Thalidomide-NH-C4-NH-Boc

Cat.No: T18807

Target: E3 Ligase Ligand-Linker Conjugate, Ligand for E3 Ligase

Thalidomide-PEG4-Propargyl

Cat.No: T9389

Synonym: Thalidomide-O-PEG4-Propargyl

Target: E3 Ligase Ligand-Linker Conjugate

cIAP1 Ligand-Linker Conjugates 4

Cat.No: T17896

Synonym: E3 ligase Ligand-Linker Conjugates 42

Target: Others

Thalidomide-O-amido-C4-NH2

Cat.No: T17818

Synonym: E3 Ligase Ligand-Linker Conjugates 19,Cereblon Ligand-Linker Conjugates 6

Target: Others

Pomalidomide-amido-C4-amido-C6-NH-Boc

Cat.No: T17907

Synonym: Cereblon Ligand-Linker Conjugates 21,E3 Ligase Ligand-Linker Conjugates 54

Target: Others

Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc

Cat.No: T17906

Synonym: E3 Ligase Ligand-Linker Conjugates 53,Cereblon Ligand-Linker Conjugates 20

Target: Others

Thalidomide-NH-PEG1-NH2 hydrochloride

Cat.No: T9401

Synonym: 4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl

Target: E3 Ligase Ligand-Linker Conjugate

(S,R,S)-AHPC-PEG4-NH2 hydrochloride

Cat.No: T15190

Synonym: E3 ligase Ligand-Linker Conjugates 7,VH032-PEG4-NH2 hydrochloride,VHL Ligand-Linker Conjugates 4 hydrochloride

Target: Others

Thalidomide-NH-C2-PEG3-OH

Cat.No: T9382

Synonym: H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]-

Target: E3 Ligase Ligand-Linker Conjugate

Lenalidomide-C4-NH2 hydrochloride

Cat.No: T17878

Synonym: Cereblon ligand 1 hydrochloride,E3 ligase Ligand-Linker Conjugates 32 hydrochloride

Target: Others

Thalidomide-O-C6-NH2 hydrochloride

Cat.No: T40031

Synonym: 4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride,萨力多胺-O-C6-氨基盐酸盐

Target: E3 Ligase Ligand-Linker Conjugate

Pomalidomide-C2-NH2

Cat.No: T17875

Synonym: Cereblon Ligand-Linker Conjugates 15,4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

Target: Others, Ligand for E3 Ligase

Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride

Cat.No: T18822

Target: Others, Ligand for E3 Ligase

Pomalidomide-PEG4-C2-NH2

Cat.No: T17916

Synonym: Cereblon Ligand-Linker Conjugates 8,E3 Ligase Ligand-Linker Conjugates 22

Target: Others, Ligand for E3 Ligase

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