Cat. No. | Product Name | Target | Signaling Pathways |
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T72982 |
DPNB-ABT594
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DPNB-ABT594 是一个硝基苄基 cage 修饰的 ABT594 ,对nAChR 的α4β2亚型的选择性比对 α7 亚型更加良好。DPNB-ABT594 可用于检查内侧缰核 (MHb) 神经元上nAChR 的分布,并有助于更深入地理解nAChR 介导的 Ca2+信号在 MHb 中的作用。 | |||
T41209 |
DPNB-ABT 594
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DPNB-ABT 594 is a nitrobenzyl-caged ABT 594, a selective α4β2 nAChR agonist. One-photon uncaging evokes large inward currents and Ca2+transients on cell bodies and dendrites of medial habenular neurons in mouse brain slices. Two-photon uncaging induces fast nAChR-mediated currents. Photolyzed with high quantum yield of 0.20. Effective photolysis occurs using one- or two-photon excitation; one-photon uncaging requires illumination at 410 nm for 1.5-3 ms; two-photon uncaging requires illumination ... |