Cat. No. | Product Name | Target | Signaling Pathways |
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T5857 |
Trametinib (DMSO solvate)
Trametinib DMSO solvate,GSK-1120212 (DMSO solvate),Trametinib dimethyl sulfoxide,JTP-74057 (DMSO solvate) |
Apoptosis; MEK | Apoptosis; MAPK |
Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) 是一种口服有效的 MEK 抑制剂,抑制 MEK1 和 MEK2 的 IC50分别为 2 nM。它还能激活自噬,诱导凋亡。 | |||
TD0004 |
Celfinder nucleic acid gel stain *10,000× concentrate in DMSO*
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Celfinder is a new kind of nucleic acid dye, which has the advantages of safety and sensitivity, and can be used as a dye for various kinds of nucleic acid electrophoresis.Unlike EB, which is highly carcinogenic, Celfinder is a flower-like dye with low to | |||
TD0003L |
CelGreen nucleic acid gel stain *10,000× concentrate in DMSO*
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CelGreen nucleic acid gel stain *10,000× concentrate in DMSO* is a fluorescent dye with a unique involvement that binds to all dsDNA double helix sulcus regions.In the free state, the side strand and CelGreen emit weak fluorescence, but the fluorescence is greatly enhanced once they are combined with the double-stranded DNA. Therefore, the fluorescence signal strength of CelGreen is related to the amount of double-stranded DNA, and the amount of double-stranded DNA in the PCR system can be detec... | |||
TD0002L |
CelRed nucleic acid gel stain *10,000× concentrate in DMSO*
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1) Non-toxicity: The unique oiliness and high molecular weight characteristics of CelRed prevent it from penetrating cell membranes into cells. Ames test results also show that the mutagenicity of CelRed dye is much less than that of EB. 2) High sensitivi | |||
TD0005 |
SYBR GREEN II
SUPER Green II RNA gel stain *10,000× concentrate in DMSO* (Electrophoresis Grade),SUPER Green II (效果同SYBR Green II)RNA染料(10,000× DMSO溶液)(电泳级) |
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1) Non-toxicity: belong to flower-stem dye, easy to biodegrade, no carcinogenic toxicity. 2) High sensitivity: at least 100pg ssDNA or RNA can be detected, which is 25 ~ 100 times higher than EB staining. 3) High SIGNal-to-noise ratio: the sample fluorescence signal is strong, while the background signal is low. 4) Simple operation: like EB, the dye does not degrade in the prefabricated gel and electrophoresis process;The dyeing process after electrophoresis takes only 30 minutes without decolor... | |||
T0341 |
Dimethyl sulfoxide
Methyl Sulfoxide,DMSO,二甲基亚砜 |
Others; Antibacterial | Microbiology/Virology; Others |
Dimethyl sulfoxide (DMSO) 是一种常用的溶剂,可溶解极性和非极性化合物。Dimethyl sulfoxide 已被广泛用于生物实验中化合物的母液配制。Dimethyl sulfoxide 具有抑菌活性。 | |||
T7659 |
Bisindolylmaleimide IV
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Others; PKC | Chromatin/Epigenetic; Cytoskeletal Signaling; Others |
Bisindolylmaleimide IV 是一种蛋白激酶 C 细胞渗透抑制剂,其 IC50范围为 0.1-0.55 μM。它也抑制 PKA,IC50范围为3.1-11.8 μM。在细胞培养中,它有效抑制人巨细胞病毒(HCMV)复制,IC50为 0.2 μM。 | |||
TD0001 |
SYBR GREEN 1
SUPER Green I (效果同SYBR Green I)核酸染料(10,000× DMSO溶液)(电泳级),SYBR(R) GREEN I NUCLEIC ACID GEL STAIN *10,000× concentrate in DMSO,SYBRGREENⅠ核苷酸胶体染料 |
Others | Others |
SYBR GREEN 1 是一种不对称花青染料,用于检测核酸。它由一个 N-烷基化的苯并噻唑或苯并恶唑环系统组成,通过一甲基桥连接到吡啶鎓或喹啉鎓环系统。 SYBR Green I 与 dsDNA 的小沟结合,在 480 nm 波长处被激发。它具有 520 nm 的峰值荧光发射。 | |||
T9242 |
Dimethyl-d6 Sulfoxide
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Others | Others |
Dimethyl-d6 Sulfoxide 是二甲基亚砜 (DMSO, (CH3) 2S = O) 的氢 (“H”) 被另一种同位素氘 (“d”) 取代的形式。二甲基-d6 亚砜是核磁共振光谱中的常用溶剂。 | |||
T38432 |
Cyanine5 NHS ester chloride
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Others | Others |
Cyanine5 NHS ester chloride 是一种具有红色荧光的活性染料,需要少量的有机共溶剂(如DMF 或DMSO)用于标记肽、蛋白质和寡核苷酸中的氨基。 | |||
T83801 |
ε-NAADP+ sodium
Etheno-NAADP,β-Nicotinic Acid-1,N6-Ethenoadenine dinucleotide phosphate,Nicotinic Acid adenine dinucleotide phosphate |
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ε-NAADP+是钙动员诱导剂NAADP的荧光衍生物。在海胆卵细胞匀浆中诱导钙释放(EC50 = 5 µM)。ε-NAADP+在275 nm和410 nm分别显示激发/发射峰值,且在DMSO中的相对发射增加了三倍。 | |||
T36254 | dTAGV-1 hydrochloride | ||
Hydrochloride salt of dTAGV-1. Suitable for use in vivo. Following ip administration of 10 mg/kg in mice: T = 4.43 h; Cmax = 2123 ng mL-1; AUCinf = 18517 hr*ng mL-1 and CL = 9.05 mL min-1 kg-1 Negative control dTAGV-1-NEG also available. Important: It is recommended that DMSO stock solutions of this compound are made and used on the same day and are not subjected to freeze/thaw. | |||
T36421 | Immuno-Oncology Screening Library | ||
The Immuno-Oncology Screening Library consists of 2 plates and contains more than 90 cancer and immunology-associated compounds in a 96-well Matrix tube rack format as 10 mM stock solutions in DMSO. This library includes a variety of immuno-oncology target modulators, including but not limited to, adenosine, CCR, CXCR, and TLR agonists and antagonists, BTK, PI3K, VEGFR, and BRAF inhibitors, PD-1/PDL-1 interaction inhibitors, and HDAC inhibitors. Please review the product insert for a full list ... |