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Cat. No. | Product Name | Target | Signaling Pathways |
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T10986 | DDX3-IN-1 | Others | Others |
DDX3-IN-1 is a DEAD-box polypeptide 3 (DDX3) inhibitor with CC50 of 50 and 36 μM for HIV and HCV, respectively. Antiviral activity. | |||
T61193 |
DDX3-IN-2
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DDX3-IN-2, a potent inhibitor of DEADbox polypeptide 3 (DDX3), demonstrates remarkable activity against the target with an IC50 value of 0.3 μM. Notably, this compound exhibits a wide range of antiviral effects, showcasing its efficacy against various viral strains. Importantly, DDX3-IN-2 exhibits the potential to overcome resistance observed in the context of HIV [1]. | |||
T6970 |
RK33
RK-33,RK 33 |
COX | Immunology/Inflammation; Neuroscience |
RK33 (RK 33) 是 DDX3(一种 RNA 解旋酶)的一流小分子抑制剂,可导致 G1 细胞周期停滞,诱导细胞凋亡,并促进 DDX3 过表达细胞的辐射增敏。 | |||
T60496 |
Ketorolac hemicalcium
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Ketorolac (RS37619) hemicalcium 是一种非选择性的 COX 抑制剂,对 COX-1 的 IC50 为 20 nM,对 COX-2 的 IC50 为 120 nM。 Ketorolac hemicalcium 是一种非甾体类抗炎药 (NSAID),可用作 0.5% 滴眼液,用于研究过敏性结膜炎、黄斑囊样水肿、术中瞳孔缩小和术后眼部炎症和疼痛等。 Ketorolac hemicalcium 也是一种可用于癌症研究的 DDX3 抑制剂 [1] [4]。 |
Cat. No. | Product Name | Species | Expression System |
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TMPH-00978 |
DDX3X Protein, Human, Recombinant (His & Myc)
DEAD box, X isoform,DEAD box protein 3, X-chromosom... |
Human | Baculovirus Insect Cells |
DDX3X Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 77 kDa and the accession number is O00571. | |||
TMPH-00977 |
DDX3X Protein, Human, Recombinant (B2M & His)
DEAD box protein 3, X-chromosomal,CAP-Rf,DDX |
Human | E. coli |
DDX3X Protein, Human, Recombinant (B2M & His) is expressed in E. coli. | |||
TMPH-02133 |
DDX39B Protein, Human, Recombinant (GST)
UAP56,HLA-B-associated transcript 1 protein,DDX... |
Human | E. coli |
Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it fun... | |||
TMPH-00979 |
DDX3Y Protein, Human, Recombinant (His & Myc)
DDX3Y,DBY,DEAD box protein 3, Y-c... |
Human | Baculovirus Insect Cells |
DDX3Y Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus. |