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Targets Recommended: Others

4

抑制剂 & 化合物

2

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T50079 2-({[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)pyrimidine-4,6-diamine

Others Others
2-({[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)pyrimidine-4,6-diamine 可用于开发新的脱氧胞苷激酶(dCK)抑制剂。
T39550 DI-87

DI-87 is a potent, orally active deoxycytidine kinase (dCK) inhibitor with high selectivity and an EC 50 of 10.2 nM. With demonstrated antitumor efficacy, DI-87 is employed in combination therapy specifically targeting tumors that express dCK.
T39114 DI-82

DI-82 is a highly potent inhibitor of deoxycytidine kinase (dCK), displaying impressive biochemical activity with an IC50 value of 27.8 nM and a K i value of 9.2 nM. Additionally, DI-82 exhibits significant antitumor effects.
T24406 L-FMAC F-18

L-(18F)-FMAC

L-FMAC F-18 has potential diagnostic activity during positron emission tomography (PET) imaging. After phosphorylation by DCK, the 18F moiety can be visualized by PET imaging.

化合物

2-({[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)pyrimidine-4,6-diamine
Cat.No: T50079
Synonym:
Target: Others
DI-87
Cat.No: T39550
Synonym:
Target:
DI-82
Cat.No: T39114
Synonym:
Target:
L-FMAC F-18
Cat.No: T24406
Synonym: L-(18F)-FMAC
Target:
Cat. No. Product Name Species Expression System
TMPJ-00922 DCK Protein, Human, Recombinant (His & T7)

DCK,Deoxycytidine Kinase

Human E. coli
Deoxycytidine Kinase (DCK) is a member of the DCK/DGK family. DCK exists as a homodimer and is localized to the nucleus. DCK is required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG), and deoxyadenosine (dA). DCK has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. In addition, DCK is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and c...
TMPY-04668 Influenza A H3N2 (A/Philippines/472/2002) (MDCK) Hemagglutinin/HA1 Protein (His)

Harvey rat sarcoma viral oncogene homolog

H3N2 HEK293 Cells
Influenza A H3N2 (A/Philippines/472/2002) (MDCK) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.9 kDa and the accession number is A0A097PF18.

重组蛋白

DCK Protein, Human, Recombinant (His & T7)
Cat.No: TMPJ-00922
Species: Human
Expression System: E. coli
Influenza A H3N2 (A/Philippines/472/2002) (MDCK) Hemagglutinin/HA1 Protein (His)
Cat.No: TMPY-04668
Species: H3N2
Expression System: HEK293 Cells
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