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Cat. No. | Product Name | Target | Signaling Pathways |
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T50079 |
2-({[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)pyrimidine-4,6-diamine
|
Others | Others |
2-({[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)pyrimidine-4,6-diamine 可用于开发新的脱氧胞苷激酶(dCK)抑制剂。 | |||
T39550 |
DI-87
|
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DI-87 is a potent, orally active deoxycytidine kinase (dCK) inhibitor with high selectivity and an EC 50 of 10.2 nM. With demonstrated antitumor efficacy, DI-87 is employed in combination therapy specifically targeting tumors that express dCK. | |||
T39114 | DI-82 | ||
DI-82 is a highly potent inhibitor of deoxycytidine kinase (dCK), displaying impressive biochemical activity with an IC50 value of 27.8 nM and a K i value of 9.2 nM. Additionally, DI-82 exhibits significant antitumor effects. | |||
T24406 |
L-FMAC F-18
L-(18F)-FMAC |
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L-FMAC F-18 has potential diagnostic activity during positron emission tomography (PET) imaging. After phosphorylation by DCK, the 18F moiety can be visualized by PET imaging. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00922 |
DCK Protein, Human, Recombinant (His & T7)
DCK,Deoxycytidine Kinase |
Human | E. coli |
Deoxycytidine Kinase (DCK) is a member of the DCK/DGK family. DCK exists as a homodimer and is localized to the nucleus. DCK is required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG), and deoxyadenosine (dA). DCK has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. In addition, DCK is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and c... | |||
TMPY-04668 |
Influenza A H3N2 (A/Philippines/472/2002) (MDCK) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/Philippines/472/2002) (MDCK) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.9 kDa and the accession number is A0A097PF18. |