Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T10970 |
DC1
|
Others | Others |
DC1 can be used to synthesize antibody-drug conjugates targeted to the treatment of cancer, is an ADC cytotoxin, similar to the small groove-binding DNA alkylating agent CC-1065. | |||
T2311 |
LDC1267
|
TAM Receptor | Tyrosine Kinase/Adaptors |
LDC1267 是一种特异性 TAM(Tyro3, Axl and Mer) 激酶抑制剂,能够作用于 Mer( IC50<5 nM)、Tyro3(IC50:8 nM) 和 Axl(IC50:29 nM)。 | |||
T10969 |
DC1SMe
|
Others | Others |
DC1 is an ADC cytotoxin, similar to the small groove-binding DNA alkylating agent CC-1065. DC1 can be used to synthesize antibody-drug conjugates targeted to the treatment of cancer. DC1Sme is a DC1 derivative with IC50 values of Ramos, Namalwa, HL60 / s | |||
T80178 |
Dc1a
|
Sodium Channel | Membrane transporter/Ion channel |
Dc1a是一种从沙漠灌木蜘蛛Diguetia canities分离的毒素,有效促进德国小蠊Nav通道(BgNav1)的开放。 | |||
T74701 |
A18-Iso5-2DC18
|
||
A18-Iso5-2DC18(compound A18)为环状类可电离阳离子脂质,具促进mRNA蛋白表达及诱导强烈介导免疫反应功能。 | |||
T82043 |
Iso5-2DC18
|
||
Iso5-2DC18是用于合成含胺脂质的化合物。该脂质适用于mRNA传递、激活STING通路及表达抗肿瘤免疫效应。 | |||
T74972 | A2-Iso5-4DC19 | ||
A2-Iso5-4DC19 为类脂化合物,有效递送多核苷酸等物质至细胞内,作为高效载体。 | |||
T10971 |
DC10SMe
|
Others | Others |
DC10SMe is a DNA alkylating agent that can be used in the synthesis of antibody-drug conjugates (ADC). The IC50 of DC10SMe for Ramos, Namalwa and HL60 / s cancer cells were 15 pM, 12 pM and 12 pM, respectively. | |||
T10974 |
DC41
|
Others | Others |
DC41 is a derivative of DC1. DC1 is a simplified analogue of CC-1065, an antibody conjugate of cytotoxic DNA alkylating agents, used for targeted treatment of cancer. | |||
T10973 |
DC41SMe
|
Others | Others |
DC41SMe is a DC1 derivative that is cytotoxic to Ramos, Namalwa and HL60 / s with IC50s ranging from 18-25 pM. DC1 is a simplified analogue of CC-1065, an antibody conjugate of cytotoxic DNA alkylation molecules, used for targeted treatment of cancer. | |||
T82048 |
IRGRILHDGAYSLTLQGLGIH
|
||
IRGRILHDGAYSLTLQGLGIH是一种针对大鼠HER2/neu的多表位II类肽。它主要应用于HER2-DC1疫苗的II类研究领域。 | |||
T82047 |
IRGRILHDGAYSLTLQGLGIH TFA
|
||
IRGRILHDGAYSLTLQGLGIH TFA为多表位II类大鼠HER2/neu肽,适用于II类HER2-DC1疫苗研究。 | |||
T81112 |
SPPHPSPAFSPAFDNLYYWDQ
|
||
SPPHPSPAFSPAFDNLYYWDQ 为多表位 II 类大鼠HER2/neu 肽,适用于 HER2-DC1 II 类疫苗研究。 | |||
T81111 |
SPPHPSPAFSPAFDNLYYWDQ TFA
|
||
SPPHPSPAFSPAFDNLYYWDQ TFA,一种II类大鼠HER2/neu多表位肽,应用于II类HER2-DC1疫苗的研究。 | |||
T10968 |
DC0-NH2
|
Others | Others |
The cytotoxicity of DC0-NH2 is 1000 times that of commonly used anti-cancer drugs (such as doxorubicin). It is the effect part of ADC. It is a simplified simulation of DC1 and has better stability. DC0-NH2 can bind to the small groove of DNA, and then ade |