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Search Results for " dbp "

Targets Recommended: EGFR

17

抑制剂 & 化合物

1

天然产物

5

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T10965	DBPR112	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	DBPR112 是一种口服有效的基于氟嘧啶的 EGFR 抑制剂，对 EGFRWT 和 EGFRL858R/T790M 的 IC50 分别为 15 nM 和 48 nM。DBPR112 可以占据 ATP 结合位点。DBPR112 具有显着的抗肿瘤功效。
T15079	DBPR108	Proteasome; DPP-4	Proteases/Proteasome; Ubiquitination
	DBPR108是新型、具有口服活性、选择性的DPP4抑制剂，IC50=为15nM，对DPP8和DPP9基本无抑制。
T27125	DBPR-110 MB110,MB 110,MB-110
	DBPR-110 is a nonstructural protein 5A (NS5A) inhibitor. DBPR-110 reduced the reporter expression of the HCV1b replicon with a EC(50) and a selective index value of 3.9 ± 0.9 pM and >12,800,000, respectively. DBPR-110 reduced HCV2a replicon activity with
T69498	DBPR112 HCl
	DBPR112 is a potent EGFR inhibitor (IC50=487 nM) as a Clinical Candidate for the Treatment of Non-Small Cell Lung Cancer. DBPR112), DBPR112 not only displayed a potent inhibitory activity against EGFRL858R/T790M double mutations but also exhibited tenfold potency better than the third-generation inhibitor, osimertinib,against EGFR and HER2 exon 20 insertion mutations. Overall, pharmacokinetic improvement through lead-to-candidate optimization yielded fourfold oral AUC better that afatinib alon...
T41063	Bromodichloronitromethane
	Bromodichloronitromethane is a Halonitromethane compound, classified as a disinfection by-product (DBP) present in drinking water.
T39869	(Z)-2-Bromo-3-methyl-2-butenedioic acid cis-2-Bromo-3-methylbutenendioic acid,(Z)-2-溴-3-甲基-2-丁二酸
	(Z)-2-Bromo-3-methyl-2-butenedioic acid is a brominated haloacid that acts as a disinfection byproduct (DBP) in finished drinking waters.
T40683	Diiodoacetic acid
	Diiodoacetic acid is a disinfection by-product (DBP) formed during water disinfection.
T40681	2,2-Dibromoacetamide
	2,2-Dibromoacetamide is a class of disinfection by-product (DBP) in drinking water.
T40827	Bromoiodoacetic acid
	Bromoiodoacetic acid is a disinfection byproduct (DBP) found in finished drinking waters, belonging to the iodinated haloacids.
T69709	GST-HG131
	GST-HG131 是一种特异性的乙肝病毒 (HBV) 表面抗原抑制剂，属于二氢苯并吡哆醛 (DBP) 类化合物。GST-HG131 抑制 HBsAg 和 HBeAg 的特异性和效力很强 (EC50=28.2 nM, 16.0 nM)。GST-HG131 还具有良好的动物安全性。
T40669	Diiodoacetamide
	Diiodoacetamide, an iodo-haloacetamide compound, emerges as a disinfection by-product (DBP) within drinking water.
T40952	Dibromochloroacetamide
	Dibromochloroacetamide, belonging to the haloacetamides class, is a disinfection byproduct (DBP) commonly found in drinking water.
T39182	1-Bromo-1,1-dichloroacetone
	1-Bromo-1,1-dichloroacetone, classified as a chlorine dioxide disinfection byproduct (DBP), is present in drinking water.
T39052	1,1-Dibromo-3-chloroacetone
	1,1-Dibromo-3-chloroacetone is an ozone-chlorine and ozone-chloramine disinfection byproduct (DBP) which is halogenated. It is formed at high bromide levels when chlorine or chloramine is utilized as a secondary disinfectant.
T40724	1,1-Dibromo-3,3-dichloroacetone
	1,1-Dibromo-3,3-dichloroacetone is a chemical compound that can be formed as a disinfection byproduct (DBP) when elevated levels of bromide are present during the use of chlorine or chloramine as secondary disinfectants, leading to the halogenation of ozone-chlorine and ozone-chloramine compounds.
T40639	1,1,3-Tribromo-3-chloroacetone
	1,1,3-Tribromo-3-chloroacetone is a chemical compound that acts as a halogenated disinfection byproduct (DBP) when elevated bromide levels are present during the use of chlorine or chloramine as a secondary disinfectant. Its formation is attributed to the reaction between ozone-chlorine and ozone-chloramine.
T40725	1,3-Dibromo-1,3-dichloroacetone
	1,3-Dibromo-1,3-dichloroacetone is a chemical compound that acts as a disinfection byproduct (DBP) of halogenated ozone-chlorine and ozone-chloramine, particularly at heightened bromide concentrations, when used as secondary disinfectants.

化合物

Cat.No: T10965

Target: EGFR

Cat.No: T15079

Target: Proteasome, DPP-4

Cat.No: T27125

Synonym: MB110,MB 110,MB-110

Cat.No: T69498

Bromodichloronitromethane

Cat.No: T41063

(Z)-2-Bromo-3-methyl-2-butenedioic acid

Cat.No: T39869

Synonym: cis-2-Bromo-3-methylbutenendioic acid,(Z)-2-溴-3-甲基-2-丁二酸

Diiodoacetic acid

Cat.No: T40683

2,2-Dibromoacetamide

Cat.No: T40681

Bromoiodoacetic acid

Cat.No: T40827

Cat.No: T69709

Diiodoacetamide

Cat.No: T40669

Dibromochloroacetamide

Cat.No: T40952

1-Bromo-1,1-dichloroacetone

Cat.No: T39182

1,1-Dibromo-3-chloroacetone

Cat.No: T39052

1,1-Dibromo-3,3-dichloroacetone

Cat.No: T40724

1,1,3-Tribromo-3-chloroacetone

Cat.No: T40639

1,3-Dibromo-1,3-dichloroacetone

Cat.No: T40725

Cat. No.	Product Name	Target	Signaling Pathways
T0606	Monobutyl Phthalate 邻苯二甲酸单丁酯,Mono-n-butyl phthalate,Butyl hydrogen phthalate	Others	Others
	Monobutyl Phthalate (Butyl hydrogen phthalateButyl hydrogen phthalate) 是邻苯二甲酸二丁酯的主要代谢物，是一种胚胎毒物，具有抗雄激素作用。

天然产物

Monobutyl Phthalate

Cat.No: T0606

Synonym: 邻苯二甲酸单丁酯,Mono-n-butyl phthalate,Butyl hydrogen phthalate

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00759	VDB Protein, Human, Recombinant (His) Group-Specific Component,DBP,VDB,GC,Gc-Globulin,Vit...	Human	HEK293 Cells
	Vitamin D-Binding Protein (DBP) is a member of the ALB/AFP/VDB family. DBP is a secreted protein and contains three albumin domains. The primary structure contains 28 cysteine residues forming multiple disulfide bonds. DBP acts as a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. DBP binds to vitamin D and its plasma metabolites and transports them to target tissues. DBP associates with membrane-bound immunoglobulin on...
TMPH-00975	DDX1 Protein, Human, Recombinant (His & Myc) DBP-RB,DDX1,ATP-dependent RNA helicase DDX1,DEAD bo...	Human	E. coli
	DDX1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPH-02178	TARDBP Protein, Human, Recombinant	Human	E. coli
	TARDBP Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 44.9 kDa and the accession number is Q13148.
TMPH-02179	TARDBP Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	TARDBP Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 44.9 kDa and the accession number is Q13148.
TMPY-00818	Granzyme H/GZMH Protein, Human, Recombinant (His) CTSGL2,CSP-C,CCP-X,granzyme H,CTLA1,CGL-2,GZMH	Human	HEK293 Cells
	Granzymes are key components of the immune response that play important roles in eliminating host cells infected by intracellular pathogens. Several granzymes are potent inducers of cell death. A total of eight granzymes (A-G and M) have been identified in the mouse, but only five are known in humans (A, B, H, M, and granzyme 3), and granzyme H appears to be specifically human. Human granzyme H is a neutral serine protease that is expressed predominantly in the lymphokine-activated killer (LAK)/...

重组蛋白

VDB Protein, Human, Recombinant (His)

Cat.No: TMPJ-00759

Species: Human

Expression System: HEK293 Cells

DDX1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-00975

Species: Human

Expression System: E. coli

TARDBP Protein, Human, Recombinant

Cat.No: TMPH-02178

Species: Human

Expression System: E. coli

TARDBP Protein, Human, Recombinant (His)

Cat.No: TMPH-02179

Species: Human

Expression System: P. pastoris (Yeast)

Granzyme H/GZMH Protein, Human, Recombinant (His)

Cat.No: TMPY-00818

Species: Human

Expression System: HEK293 Cells

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