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Search Results for " d-ribose "

13

抑制剂 & 化合物

8

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T24018	D-Ribose-L-cysteine DRiboseLcysteine,Ribcys,Riboceine,J424.013H,D Ribose L cysteine
	D-Ribose-L-cysteine is the antioxidant glutathione precursor.
T77194L	D-Ribose 5-phosphate disodium dihydrate
	D-Ribose 5-phosphate disodium dihydrate 是戊糖磷酸途径 (PPP) 氧化分支的中间产物，是 PPP 非氧化分支的终产物。D-Ribose 5-phosphate 用于核苷酸和核酸的合成。
T36973	5-Phospho-D-ribose 1-diphosphate (sodium salt hydrate)
	5-Phospho-D-ribose 1-diphosphate (PRPP) is a natural intermediate involved in the pentose phosphate pathway leading to purine, pyrimidine, and histidine metabolism. It is also an intermediate in the synthesis of plant hormones, alkaloids, and other secondary metabolites from glucose. Several phosphoribosyltransferases (PRTases) use PRPP as a substrate to add a 5-phosphoribosyl group to another substrate, as in the production of adenosine monophosphate from adenine and PRPP by adenine PRTase. N/A
TNU0755	1-(a,b)-O-methyl-3,5-di-(O-p-toluoyl)-2-deoxy-D-ribose
	1-(a,b)-O-methyl-3,5-di-(O-p-toluoyl)-2-deoxy-D-ribose is a Carbohydrate derivative.
T6425	BTZ043 Racemate BTZ044,BTZ10526038,Benzothiazinone 10526038	Antibacterial; DprE1	Microbiology/Virology; Others
	BTZ043 Racemate (Benzothiazinone 10526038) 是一种癸二烯基磷酰-β-D-核糖 2'-差向异构酶(DprE1) 抑制剂，用作新的抗分枝杆菌剂。
T3583	Macozinone PBTZ169	Antibacterial; DprE1	Microbiology/Virology; Others
	Macozinone (PBTZ169) 是具有杀菌作用的苯并噻嗪酮，也有抗结核作用。它也是一种 DprE1有效抑制剂，可通过与活性位点 Cys387 残基形成共价键来抑制必需的黄素蛋白 DprE1。
T73783	D-Ribofuranose
	D-Ribofuranose (D-Ribose) 是一种在脑脊液中发现的内源性代谢物，用于磷酸 5 核糖异构酶缺乏症和中链酰基 CoA 脱氢酶缺乏症的研究。
T39467	Methyl 2,3-O-Isopropylidene-β-L-ribofuranoside
	Methyl 2,3-O-Isopropylidene-β-L-ribofuranoside is an enantiomeric derivative of L-ribose, specifically Methyl 2,3-O-Isopropylidene-β-D-ribofuranoside.
T74046	D-Ribofuranose1-dihydrogenphosphate dicyclohexanamine
	D-Ribofuranose1-dihydrogenphosphate dicyclohexanamine，即1-磷酸核糖，作为核苷酸合成的关键中间体，在5-氟尿嘧啶(FUra)的磷酸化过程中，被尿苷磷酸化酶催化转化为核苷。
T63319	Antitubercular agent-32
	Antitubercular agent-32 是Benzothiazinone 衍生物，对结核分枝杆菌 M. tuberculosis 具有抑制作用，并表现出良好的代谢稳定性及水溶性。 Antitubercular agent-32 可以作用于 decaprenylphosphoryl-β-D-ribose 2'-氧化酶 (DprE1,IC50: 3.9 μM)，表现出抗结核效果。
T37987	D-Ribulose
	Ribulose is a ketopentose, a monosaccharide containing five carbon atoms and a ketone functional group. It is synthesized in the pentose phosphate pathway and plays a role in the formation of various bioactive compounds. It is a structural isomer of ribose and exists as two enantiomers, D-ribulose and L-ribulose. A double phosphate ester of D-ribulose, ribulose-1,5-bisphosphate combines with carbon dioxide at the beginning of photosynthesis.
T75074	6-Methoxypurine-9-β-D-5’(R)-C-methylriboside
	6-Methoxypurine-9-β-D-5’(R)-C-methylriboside 是一种嘌呤碱基，属于次黄嘌呤似物，主要在肌肉组织中发现。作为黄嘌呤在嘌呤氧化酶作用下的代谢产物，次黄嘌呤具备显著的抗炎性质，并可作为内源性 poly(ADP-ribose) polymerase (PARP) 的抑制剂。其通过抑制 PARP 活性，防止过氧亚硝酸盐引起的线粒体去极化及次级超氧化物的产生，展现出细胞保护作用。同时，次黄嘌呤也被用作缺氧的生物标志物。
T36703	CAY10760
	CAY10760 is an inhibitor of the protein-protein interaction between RAD51 recombinase and BRCA2 (EC50= 19 μM in a cell-free competitive ELISA).1It decreases homologous recombination by 54% in wild-typeBRCA2-expressing BxPC-3 pancreatic cancer cells when used at a concentration of 20 μM. CAY10760 (20 μM) decreases proliferation of BxPC-3, as well as mutantBRCA2-expressing Capan-1, cancer cells when used alone or in combination with the poly(ADP-ribose) polymerase (PARP) inhibitor olaparib . 1.Bag...

化合物

D-Ribose-L-cysteine

Cat.No: T24018

Synonym: DRiboseLcysteine,Ribcys,Riboceine,J424.013H,D Ribose L cysteine

D-Ribose 5-phosphate disodium dihydrate

Cat.No: T77194L

5-Phospho-D-ribose 1-diphosphate (sodium salt hydrate)

Cat.No: T36973

1-(a,b)-O-methyl-3,5-di-(O-p-toluoyl)-2-deoxy-D-ribose

Cat.No: TNU0755

BTZ043 Racemate

Cat.No: T6425

Synonym: BTZ044,BTZ10526038,Benzothiazinone 10526038

Target: Antibacterial, DprE1

Cat.No: T3583

Synonym: PBTZ169

Target: Antibacterial, DprE1

Cat.No: T73783

Methyl 2,3-O-Isopropylidene-β-L-ribofuranoside

Cat.No: T39467

D-Ribofuranose1-dihydrogenphosphate dicyclohexanamine

Cat.No: T74046

Antitubercular agent-32

Cat.No: T63319

Cat.No: T37987

6-Methoxypurine-9-β-D-5’(R)-C-methylriboside

Cat.No: T75074

Cat.No: T36703

Cat. No.	Product Name	Target	Signaling Pathways
T4786	D-Ribose(mixture of isomers) D-Ribose,D-(-)-Ribose,D-(-)-核糖	Others; Endogenous Metabolite	Metabolism; Others
	D-Ribose(mixture of isomers) (D-(-)-Ribose) 是 ATP 的糖部分，可作为能量增强剂，被广泛用作慢性疲劳综合症和心肌能量代谢的代谢疗法补充剂。它在蛋白质糖化中具有特性，能够 RAGE 依赖的方式诱导 NF-Κb 炎症。
T19267	D-Ribose 5-phosphate	Others	Others
	Ribose 5-phosphate is the intermediate product of the oxidative branch of the pentose phosphate pathway (PPP) and the final product of the non-oxidative branch of PPP. Ribose 5-phosphate is used in the synthesis of nucleotides and nucleic acids.
T4818	Thyminose 2-脱氧-D-核糖,2-Deoxy-D-ribose,2-Deoxy-D-arabinose,2-Deoxy-D-erythropentose	Others; Endogenous Metabolite	Metabolism; Others
	Thyminose (2-Deoxy-D-arabinose) 通过抑制谷胱甘肽的合成和增加其外排诱导细胞凋亡。
T2221	Uridine Uridin,β-Uridine,NSC 20256,尿苷	Others; Endogenous Metabolite	Metabolism; Others
	Uridine (Uridin) 是一种核苷化合物, 由核糖环和尿嘧啶组成, 两者通过β-N1-配糖键链接。
T0853	Adenosine 腺苷,D-Adenosine,Adenine riboside	Apoptosis; Nucleoside Antimetabolite/Analog; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Adenosine (D-Adenosine) 是一种核糖核苷，由与核糖结合的腺嘌呤组成，具有血管扩张、抗心律失常和镇痛作用。
T6640	Ribitol 核糖醇,Adonite,阿东糖醇,Adonitol	Others; Endogenous Metabolite	Metabolism; Others
	Ribitol (Adonite) 是一种戊糖醇，能够通过核糖还原形成。在酿酒酵母中增强 D-葡萄糖转向戊糖磷酸途径，能够用于生产核糖醇和 D-核糖。
T1591L	Cytidine Cytosine-1-β-D-ribofuranoside,胞苷,Cytosine β-D-riboside	Nucleoside Antimetabolite/Analog; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Cytidine (Cytosine-1-β-D-ribofuranoside) 是一种嘧啶核苷，由通过 β-N1-糖苷键与核糖结合的胞嘧啶组成。它是尿苷的前体，用于 RNA 合成。
T4737	2'-Deoxyadenosine-5'-monophosphate D-AMP,2′-脱氧腺苷-5′-单磷酸,2'-Deoxyadenosine 5'-monophosphate,2'-脱氧腺苷-5'-单磷酸	Others; Endogenous Metabolite	Metabolism; Others
	2'-Deoxyadenosine-5'-monophosphate (D-AMP) 是一种存在于 DNA 中的脱氧核糖核苷酸，是一种核酸 AMP 衍生物。它能够用于研究 DNA 合成和 DNA 损伤过程中基于腺苷的相互作用。

天然产物

D-Ribose(mixture of isomers)

Cat.No: T4786

Synonym: D-Ribose,D-(-)-Ribose,D-(-)-核糖

Target: Others, Endogenous Metabolite

D-Ribose 5-phosphate

Cat.No: T19267

Target: Others

Cat.No: T4818

Synonym: 2-脱氧-D-核糖,2-Deoxy-D-ribose,2-Deoxy-D-arabinose,2-Deoxy-D-erythropentose

Target: Others, Endogenous Metabolite

Cat.No: T2221

Synonym: Uridin,β-Uridine,NSC 20256,尿苷

Target: Others, Endogenous Metabolite

Cat.No: T0853

Synonym: 腺苷,D-Adenosine,Adenine riboside

Target: Apoptosis, Nucleoside Antimetabolite/Analog, Endogenous Metabolite, Autophagy

Cat.No: T6640

Synonym: 核糖醇,Adonite,阿东糖醇,Adonitol

Target: Others, Endogenous Metabolite

Cat.No: T1591L

Synonym: Cytosine-1-β-D-ribofuranoside,胞苷,Cytosine β-D-riboside

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite

2'-Deoxyadenosine-5'-monophosphate

Cat.No: T4737

Synonym: D-AMP,2′-脱氧腺苷-5′-单磷酸,2'-Deoxyadenosine 5'-monophosphate,2'-脱氧腺苷-5'-单磷酸

Target: Others, Endogenous Metabolite

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