Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN6722 |
Terminolic acid
2α,6β,23-trihydroxyl oleanolic acid |
Antibacterial | Microbiology/Virology |
Terminolic acid (2α,6β,23-trihydroxyl oleanolic acid) 是一种从 Combretum racemosum 中分离得到的五环三萜糖苷,可通过与 IL-1β 和 IL-6 的受体活性位点结合抑制促炎细胞因子,并通过与 IL-4 受体结合位点结合增强抗炎细胞因子。它还表现出适度的抗菌活性。 | |||
TN6508 |
Trachelogenin
(-)-Trachelogenin |
Virus Protease; c-Myc; HCV Protease; Wnt/beta-catenin | Cell Cycle/Checkpoint; Cytoskeletal Signaling; Microbiology/Virology; Proteases/Proteasome; Stem Cells |
Trachelogenin ((-)-Trachelogenin) 分离自Combretum fruticosum,是一种 HCV 进入抑制剂 具有抗增殖作用,其机制与影响β-Catenin 信号通路中的 β-Catenin、c-Myc 和 GSK3 等关键蛋白的磷酸化有关,且呈浓度依赖性。Trachelogenin具有抗病毒、抗炎和镇痛活性,在 HCVcc 和 HCVpp 模型中的 IC50 分别为 0.325 和 0.259 μg/mL。 | |||
T83368 |
3,5-Dimethoxy-2,7-phenanthrenediol
|
||
3,5-Dimethoxy-2,7-phenanthrenediol (compound 2),一種從Combretum laxum根部分離的菲類化合物,對786-0、MCF-7及NCI/ADR-RES人癌細胞系展現出顯著的細胞毒性,其IC50s值分別為73.26 μM、118.40 μM以及83.99 μM。該化合物還表現出自由基清除活性,其IC50為20.4 μM。 | |||
TN2813 |
23-deoxojessic acid
|
Others | Others |
23-Deoxojessic acid possesses strong cytotoxicity towards highly liver metastatic murine colon 26-L5 carcinoma cells, with ED50 values equal to or less than 6 microM. | |||
TN1203 |
2,3,8-Tri-O-methylellagic acid
2,3,8-三邻甲基鞣花酸 |
Antifection | Microbiology/Virology |
2,3,8-tri-O-Methyl ellagic acid has antimicrobial activity agaist Vibro cholera, Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Bacillus cereus, Escherichia coli. |