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Cat. No. Product Name Target Signaling Pathways
TP1040 Calcitonin (salmon)

鲑降钙素,Calcitonin salmon,Salmon calcitonin

 CGRP Receptor GPCR/G Protein; Neuroscience
Calcitonin (salmon) 是一种阿米林和卡西宁受体的双激动剂，是一种钙调节激素，能够刺激骨的生成并能抑制骨吸收。
TP1040L Calcitonin（salmon） Acetate(47931-85-1(free base))

Salmon calcitonin

 CGRP Receptor GPCR/G Protein; Neuroscience
Calcitonin(salmon)Acetate (47931-85-1(free base))(Salmon calcitonin) 是一种钙调节激素，用于治疗绝经后至少 5 年的女性骨质疏松症。
TP1028L Calcitonin eel acetate

Calcitonin eel acetate (57014-02-5 Free base),降钙素,Thyrocalcitonin eel

 Others Others
Calcitonin eel acetate (Calcitonin eel acetate (57014-02-5 Free base)) 是调节钙稳态的甲状腺激素肽。
TP1200 CGRP (83-119), rat TFA

Calcitonin Gene Related Peptide(83-119), rat TFA

 Others Others
CGRP (83-119), rat TFA (Calcitonin Gene Related Peptide(83-119), rat TFA) 是一种由 37 个氨基酸组成的神经肽降钙素家族，通过降钙素受体样受体起作用。
T37413 Calcitonin (salmon) (trifluoroacetate salt)

Calcitonin is a peptide hormone that lowers blood calcium level and inhibits bone resorption. It belongs to the calcitonin family of peptides, which also includes amylin , calcitonin gene-related peptide , and adrenomedullin. The binding of salmon calcitonin to the human calcitonin receptor (CTR) is not modulated by receptor activity-modifying proteins (RAMPs), which influence affinity of human calcitonin to CTR. Salmon calcitonin binds to human CTR2 with IC50 values of 0.933, 0.224, 0.134, and ...
TP2055 Calcitonin (human)

Endogenous calcitonin receptor agonist. Lowers systemic blood calcium levels and inhibits bone resorption.
TP1027 Calcitonin, eel TFA (57014-02-5 free base)

Thyrocalcitonin eel (TFA),Calcitonin, eel TFA
Calcitonin,eel TFA is a thyroid hormone polypeptide that can regulate calcium homeostasis and is widely used in the study of postmenopausal osteoporosis.
TP1028 Calcitonin, eel

Thyrocalcitonin eel
Calcitonin, eel is a peptide hormone that plays a crucial role in maintaining calcium balance within the body. It is extensively utilized in the scientific investigation of postmenopausal osteoporosis, a condition characterized by decreased bone density and an increased risk of fractures in women after menopause.
T78372 Calcitonin, eel TFA

Thyrocalcitonin eel TFA
Calcitonin, eel TFA，一种甲状腺激素多肽，调节钙稳态，主要应用于绝经后骨质疏松症研究。
TP1677 Calcitonin (8-32), salmon

Calcitonin (8-32), salmon is a highly selective amylin receptor antagonist.Calcitonin is a hormone known to participate in calcium and phosphorus metabolism. In mammals, the major source of calcitonin is from the parafollicular or C cells in the thyroid g
TP1202 Calcitonin Gene Related Peptide (CGRP) II, rat

CGRP II, rat
Calcitonin Gene Related Peptide II is a potent, long-lasting vasodilator; activation of CGRP receptors on pancreatic β-cells increases plasma levels of pancreatic enzymes.
TP1203 CGRP(83-119), rat

Calcitonin Gene Related Peptide (CGRP) (83-119), rat
Calcitonin Gene Related Peptide (CGRP) (83-119), rat is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor.
TP1201 CGRP II, rat (TFA) (99889-63-1 free base)

Calcitonin Gene Related Peptide (CGRP) II, rat (TFA),CGRP II, rat (TFA)
Calcitonin Gene Related Peptide (CGRP) II, rat (TFA) is a neuropeptide with 37 amino acid.
T17194 Ubrogepant

MK-1602

 CGRP Receptor GPCR/G Protein; Neuroscience
Ubrogepant (MK-1602) 是新型的、口服有效的降钙素基因相关肽受体拮抗剂。Ubrogepant 有潜力用于急性偏头痛的相关研究。
T76363 [Tyr22] Calcitonin Gene Related Peptide, (22-37), rat

[Tyr22]CalcitoninGene Related Peptide, (22-37), rat 是一种大鼠降钙素基因相关肽 (CGRP) 的 22-37 片段，靶向CGRP 受体和腺苷酸环化酶。降钙素 (calcitonin) 主要由甲状腺 C 细胞产生，而 CGRP 则分泌并储存在神经系统中。
T76032 Calcitonin Gene Related Peptide (CGRP) II, rat TFA

CalcitoninGene Related Peptide (CGRP) II, rat TFA，为CGRP受体激活剂，具有显著且持久的血管扩张效果，适用于心血管疾病研究。
T12293L Olcegepant

BIBN-4096,BIBN 4096BS

 CGRP Receptor GPCR/G Protein; Neuroscience
Olcegepant (BIBN-4096) 是一种选择性的降钙素基因相关肽1 (CGRP1) 受体拮抗剂，IC50=0.03 nM，Ki=14.4 pM。
T8682 Vazegepant hydrochloride

Vazegepant HCl

 CGRP Receptor GPCR/G Protein; Neuroscience
Vazegepant hydrochloride (Vazegepant HCl) 是一种用于偏头痛的鼻用 gepant，是一种高度亲和性CGRP 受体拮抗剂 (hCGRPKi=0.023 nM)。它可能有助于有效管理 COVID-19 相关肺部炎症。
T4610 Rimegepant

BMS 927711,BMS-927711,BMS927711,BHV-3000

 CGRP Receptor GPCR/G Protein; Neuroscience
Rimegepant (BMS 927711) 是一种有效的降钙素基因相关肽 (CGRP) 受体拮抗剂，其 Ki=0.027 nM，IC50=0.14 nM。
T6590 MK-3207 Hydrochloride

MK-3207 HCl

 CGRP Receptor GPCR/G Protein; Neuroscience
MK-3207 Hydrochloride (MK-3207 HCl) 是口服具有活力的CGRP receptor 拮抗剂，IC50=0.12 nM，Ki=0.024 nM。
TP2233L CGRP (rat) acetate

Others Others
CGRP (rat) acetate 是一种降钙素基因相关肽（CGRP）。它是一种有效的血管扩张剂。
TP1257L Adrenomedullin (AM) (22-52), human acetate

Adrenomedullin (AM) (22-52), human acetate（159899-65-7 Free base）

 CGRP Receptor GPCR/G Protein; Neuroscience
Adrenomedullin (AM) (22-52), human acetate 是猫后肢血管床中 CGRP 受体和肾上腺髓质素受体的拮抗剂。
T76874 Erenumab

AMG-334

 CGRP Receptor GPCR/G Protein; Neuroscience
Erenumab是一种全人单克隆抗体，作用于抑制降钙素基因相关肽(CGRP)受体，用于预防发作性偏头痛。
TP1134L HCGRP-(8-37) acetate

HCGRP-(8-37) acetate (119911-68-1 free base)

 CGRP Receptor GPCR/G Protein; Neuroscience
HCGRP-(8-37) acetate 是一种人降钙素基因相关肽 (hCGRP) 片段醋酸盐，也是 CGRP 受体的拮抗剂。
T76682 Galcanezumab

LY 2951742

 CGRP Receptor GPCR/G Protein; Neuroscience
Galcanezumab 是一种靶向 CGRP 配体的人源化 IgG4 单克隆抗体，是一种与配体降钙素基因相关肽结合的抗体。Galcanezumab 可用于预防和治疗偏头痛或丛集性头痛。
T23406 SUN B8155

SUN-B 8155

 Others Others
calcitonin (CT) receptor agonist
T26682 Atogepant

MK 8031,MK8031. Atogepant,MK-8031
Atogepant is an antagonist of calcitonin gene-related peptide receptor.
TP2049 CRSP-1

Endogenous central calcitonin (CT) receptor agonist that stimulates cAMP formation at a potency 350-fold greater than CT (ED50 values are 0.2 and 71 nM respectively). Displays no activity at calcitonin-gene related peptide (CGRP) and adrenomedullin recept
T39522 HTL22562

HTL22562 is a calcitonin gene-related peptide (CGRP) receptor antagonist for acute treatment of migraine.
T12293 Olcegepant hydrochloride

BIBN-4096 hydrochloride,BIBN4096BS hydrochloride

 Others Others
Olcegepant hydrochloride is a potent and selective non-peptidethe calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (with IC50 of 0.03 nM for human CGRP).
TP1131 β-CGRP, human TFA (101462-82-2 free base)

CGRP-II (Human) (TFA),Human β-CGRP (TFA),β-CGRP, human TFA
β-CGRP,human tissue is one of the calcitonin peptide, through complex behavior of calcitonin receptor like receptor (CRLR) - and receptor activity - modifying proteins (increased), and 1 and 300 - nM CRLR IC50s/RAMP1 and CRLR/RAMP2 cells.
T75978 β-CGRP, human TFA

β-CGRP, human TFA (Human β-CGRP TFA) 是一种降钙素肽，通过降钙素受体样受体CRLR 与RAMP 的复合物起作用，在细胞体系中，对 CRLR/RAMP1 和 CRLR/RAMP2 的IC50值分别为 1 nM 和 300 nM。
TP2044 α-CGRP(human)

α-CGRP (human)
Endogenous calcitonin gene-related peptide receptor (CGRP) agonist.
T26796 BI-44370

BI-44370, a CGRP (calcitonin gene-related peptide) receptor antagonist, can be used to treat migraines and other chronic pain.
T70248 4991W93

4991W93 is a 5HT(1B/1D) receptor partial agonist, inhibiting electrically induced plasma extravasation, blocking neurogenic plasma protein extravasation, inhibiting release of calcitonin gene-related peptide.
T16093 Telcagepant

MK-0974

 Others Others
Telcagepant is an orally active antagonist of calcitonin gene-related peptide (CGRP) receptor (Kis: 0.77 nM and 1.2 nM for human and rhesus CGRP receptors, respectively).
T71246 DD04107

DD04107 is a novel inhibitor of α-calcitonin gene-related peptide (α-CGRP) exocytotic release from primary sensory neurons, selectively interacting with Synaptotagmin 1.
T27025 Cizolirtine citrate

E-4018,E4018,E 4018
Cizolirtine is a calcitonin gene-related peptide antagonist. Cizolirtine may be useful for alleviating some neuropathic somatosensory disorders, in particular cold allodynia, with a reduced risk of undesirable side effects. Cizolirtine inhibits the spinal
TP1130 β-CGRP, human

CGRP-II (Human),Human β-CGRP
β-CGRP, human ,a 37-amino acid peptide,is the beta form of Calcitonin-gene-related peptide (β-CGRP), involved extensively in regulation of the cardiovascular and nervous systems. β-CGRP contains a disulphide bridge at the N-terminus, a C-terminal phenylal
T73703 (3R,5R,6S)-Atogepant

(3R,5R,6S)-Atogepant ((3R,5R,6S)-MK-8031) 是Atogepant 的异构体.Atogepant 是降钙素基因相关肽受体 (CGRP) 拮抗剂。Atogepant 可用于研究偏头痛。
T76678 Eptinezumab

Eptinezumab为人源化单克隆抗体，主要通过与降钙素基因相关肽(CGRP)结合，进而阻止其与受体相结合，用于成人偏头痛的预防。
TP1232 Amylin, amide, rat

Amylin (rat)
Amylin is a peptide that displays 50% homology with calcitonin gene-related peptide (CGRP), Amylin is colocalized with somatostatin in endocrine cells of the gastric fundus. In isolated mouse stomach, amylin caused a concentration-dependent decrease in ac
TP1625 Adrenomedullin (11-50), rat

Adrenomedullin 11-50 rat is a peptide fragment of adrenomedullin that possesses systemic vasodilator activity at the level of calcitonin gene-related peptide-1 (CGRP1) receptor activation. Adrenomedullin and its peptide may be used in bone growth studies.
TP1954 PHM-27 (human)

Endogenous peptide product of human prepro-VIP and analog of porcine PHI-27; potent agonist for the human calcitonin receptor (EC50 = 11 nM). Transgenic mice expressing the human VIP/PHM 27 gene in pancreatic β-islets display enhanced glucose-induced insu
TP1183 Amylin, amide, human

DAP amide, human
Amylin, a 37-amino acid polypeptide that is structurally related to calcitonin, is secreted from the B cells of the pancreas. Amylin has anoretic effects in rats. Amylin may be responsible for the etiology of insulin resistance of type II diabetes mellitu
T70837 Rimegepant sulfate hydrate

Rimegepant, also known as BMS-927711 and BHV-3000, is a potent, selective, competitive, and orally active calcitonin gene-related peptide (CGRP) antagonist in clinical trials for treating migraines. Rimegepant has shown in vivo efficacy without vasoconstriction effect. BMS-927711 is superior to placebo at several different doses (75 mg, 150 mg, and 300 mg) and has an excellent tolerability profile.
T76262 Cagrilintide

Cagrilintide为一种处于研发阶段的新型长效酰化胰岛素类似物，兼具非选择性胰岛素受体(AMYR)与降钙素G蛋白偶联受体(CTR)的激动剂功能。该化合物能显著降低体重并减少食物摄入，展现出针对肥胖疾病的研究潜力。
T76680 Fremanezumab

Fremanezumab (TEV-48125) 是一种人源化IgG2a 单克隆抗体，可选择性且有效地与降钙素基因相关肽 (CGRP) 结合。CGRP 是一种 37 个氨基酸的神经肽，参与偏头痛的中枢和外周病理生理事件。Fremanezumab 具有用于慢性偏头痛研究的潜力。
T75934 AC 187 TFA

AC 187 TFA 是一种有效且具有口服活性的胰淀素受体 (amylin receptor) 拮抗剂，IC50为 0.48 nM，Ki 为 0.275 nM。AC 187 TFA 对胰淀素受体的选择性高于降钙素和 CGRP 受体。AC 187 TFA 具有神经保护作用。
T36555 Tyr-α-CGRP (human) (trifluoroacetate salt)

Tyr-α-CGRP is an N-terminal extended tyrosinated analogue of α-calcitonin gene-related peptide . It binds to amylin receptors AMY1 and AMY3 in COS-7 cells expressing the human receptors (IC50s = 141 and 1.86 nM, respectively). Tyr-α-CGRP also binds to and stimulates cAMP accumulation in rat L6 myocytes (IC50 = 4 nM; EC50 = 12 nM). It also binds to rat brain and spleen membrane preparations (IC50s = 0.2 and 0.5 nM, respectively), induces positive chronotropic and inotropic effects in isolated rig...

化合物

Calcitonin (salmon)
Cat.No: TP1040
Synonym: 鲑降钙素,Calcitonin salmon,Salmon calcitonin
Target: CGRP Receptor
Calcitonin（salmon） Acetate(47931-85-1(free base))
Cat.No: TP1040L
Synonym: Salmon calcitonin
Target: CGRP Receptor
Calcitonin eel acetate
Cat.No: TP1028L
Synonym: Calcitonin eel acetate (57014-02-5 Free base),降钙素,Thyrocalcitonin eel
Target: Others
CGRP (83-119), rat TFA
Cat.No: TP1200
Synonym: Calcitonin Gene Related Peptide(83-119), rat TFA
Target: Others
Calcitonin (salmon) (trifluoroacetate salt)
Cat.No: T37413
Synonym:
Target:
Calcitonin (human)
Cat.No: TP2055
Synonym:
Target:
Calcitonin, eel TFA (57014-02-5 free base)
Cat.No: TP1027
Synonym: Thyrocalcitonin eel (TFA),Calcitonin, eel TFA
Target:
Calcitonin, eel
Cat.No: TP1028
Synonym: Thyrocalcitonin eel
Target:
Calcitonin, eel TFA
Cat.No: T78372
Synonym: Thyrocalcitonin eel TFA
Target:
Calcitonin (8-32), salmon
Cat.No: TP1677
Synonym:
Target:
Calcitonin Gene Related Peptide (CGRP) II, rat
Cat.No: TP1202
Synonym: CGRP II, rat
Target:
CGRP(83-119), rat
Cat.No: TP1203
Synonym: Calcitonin Gene Related Peptide (CGRP) (83-119), rat
Target:
CGRP II, rat (TFA) (99889-63-1 free base)
Cat.No: TP1201
Synonym: Calcitonin Gene Related Peptide (CGRP) II, rat (TFA),CGRP II, rat (TFA)
Target:
Ubrogepant
Cat.No: T17194
Synonym: MK-1602
Target: CGRP Receptor
[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat
Cat.No: T76363
Synonym:
Target:
Calcitonin Gene Related Peptide (CGRP) II, rat TFA
Cat.No: T76032
Synonym:
Target:
Olcegepant
Cat.No: T12293L
Synonym: BIBN-4096,BIBN 4096BS
Target: CGRP Receptor
Vazegepant hydrochloride
Cat.No: T8682
Synonym: Vazegepant HCl
Target: CGRP Receptor
Rimegepant
Cat.No: T4610
Synonym: BMS 927711,BMS-927711,BMS927711,BHV-3000
Target: CGRP Receptor
MK-3207 Hydrochloride
Cat.No: T6590
Synonym: MK-3207 HCl
Target: CGRP Receptor
CGRP (rat) acetate
Cat.No: TP2233L
Synonym:
Target: Others
Adrenomedullin (AM) (22-52), human acetate
Cat.No: TP1257L
Synonym: Adrenomedullin (AM) (22-52), human acetate（159899-65-7 Free base）
Target: CGRP Receptor
Erenumab
Cat.No: T76874
Synonym: AMG-334
Target: CGRP Receptor
HCGRP-(8-37) acetate
Cat.No: TP1134L
Synonym: HCGRP-(8-37) acetate (119911-68-1 free base)
Target: CGRP Receptor
Galcanezumab
Cat.No: T76682
Synonym: LY 2951742
Target: CGRP Receptor
SUN B8155
Cat.No: T23406
Synonym: SUN-B 8155
Target: Others
Atogepant
Cat.No: T26682
Synonym: MK 8031,MK8031. Atogepant,MK-8031
Target:
CRSP-1
Cat.No: TP2049
Synonym:
Target:
HTL22562
Cat.No: T39522
Synonym:
Target:
Olcegepant hydrochloride
Cat.No: T12293
Synonym: BIBN-4096 hydrochloride,BIBN4096BS hydrochloride
Target: Others
β-CGRP, human TFA (101462-82-2 free base)
Cat.No: TP1131
Synonym: CGRP-II (Human) (TFA),Human β-CGRP (TFA),β-CGRP, human TFA
Target:
β-CGRP, human TFA
Cat.No: T75978
Synonym:
Target:
α-CGRP(human)
Cat.No: TP2044
Synonym: α-CGRP (human)
Target:
BI-44370
Cat.No: T26796
Synonym:
Target:
4991W93
Cat.No: T70248
Synonym:
Target:
Telcagepant
Cat.No: T16093
Synonym: MK-0974
Target: Others
DD04107
Cat.No: T71246
Synonym:
Target:
Cizolirtine citrate
Cat.No: T27025
Synonym: E-4018,E4018,E 4018
Target:
β-CGRP, human
Cat.No: TP1130
Synonym: CGRP-II (Human),Human β-CGRP
Target:
(3R,5R,6S)-Atogepant
Cat.No: T73703
Synonym:
Target:
Eptinezumab
Cat.No: T76678
Synonym:
Target:
Amylin, amide, rat
Cat.No: TP1232
Synonym: Amylin (rat)
Target:
Adrenomedullin (11-50), rat
Cat.No: TP1625
Synonym:
Target:
PHM-27 (human)
Cat.No: TP1954
Synonym:
Target:
Amylin, amide, human
Cat.No: TP1183
Synonym: DAP amide, human
Target:
Rimegepant sulfate hydrate
Cat.No: T70837
Synonym:
Target:
Cagrilintide
Cat.No: T76262
Synonym:
Target:
Fremanezumab
Cat.No: T76680
Synonym:
Target:
AC 187 TFA
Cat.No: T75934
Synonym:
Target:
Tyr-α-CGRP (human) (trifluoroacetate salt)
Cat.No: T36555
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TP2167 β-CGRP, human acetate

β-CGRP, human acetate (101462-82-2 free),CGRP-II (Human) (acetate),Human β-CGRP acetate

 CGRP Receptor GPCR/G Protein; Neuroscience
β-CGRP, human acetate 是降钙素肽之一，通过受体活性修饰蛋白 (RAMP) 和降钙素受体样受体 (CRLR) 的复合物发挥作用（对于 CRLR/RAMP1 和 CRLR，IC50：1 nM 和 300 nM /RAMP2 在单元格中）。
T15157 Dodecanoylcarnitine

Lauroylcarnitine

 Endogenous Metabolite Metabolism
Dodecanoylcarnitine（(-)-Lauroylcarnitine） 和脂肪酸氧化紊乱有关，使用 Dodecanoylcarnitine 可使鲑鱼降钙素的通透性增加。
T21581L AC 187 Acetate

AC 187 Acetate (151804-77-2 Free base)

 Amylin Receptor GPCR/G Protein
AC 187 Acetate 是胰淀素受体的强效拮抗剂。AC 187 对胰淀素受体的选择性高于降钙素和 CGRP 受体。

天然产物

β-CGRP, human acetate
Cat.No: TP2167
Synonym: β-CGRP, human acetate (101462-82-2 free),CGRP-II (Human) (acetate),Human β-CGRP acetate
Target: CGRP Receptor
Dodecanoylcarnitine
Cat.No: T15157
Synonym: Lauroylcarnitine
Target: Endogenous Metabolite
AC 187 Acetate
Cat.No: T21581L
Synonym: AC 187 Acetate (151804-77-2 Free base)
Target: Amylin Receptor
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