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Search Results for " ctla4 "

4

抑制剂 & 化合物

18

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T80573	Firastotug
	Firastotug为针对CTLA4的IgG1κ抗体。CTLA4作为细胞毒性T淋巴细胞相关抗原，它在自身免疫和癌症研究中扮演着重要的免疫检查点角色。
T81736	Muzastotug
	Muzastotug为人源化免疫球蛋白G1-kappa型，针对CTLA4的单克隆抗体，兼具免疫刺激剂及抗肿瘤药物功能。
T10218	Abatacept CTLA4lg	Others	Others
	Abatacept (CTLA4lg) is a soluble fusion protein consisting of the extracellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1 (hinge and CH2 and 3 domains). It is a selective T-cell co-stimulation modulator and a protein drug for au
T76716	Cadonilimab
	Cadonilimab (AK104) 为一种IgG1支架Fc工程化的人源化抗体，针对PD1/CTLA4。适用于转移性宫颈癌研究。

化合物

Cat.No: T80573

Cat.No: T81736

Cat.No: T10218

Synonym: CTLA4lg

Target: Others

Cat.No: T76716

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00112	CTLA-4 Protein, Human, Recombinant (His & Avi), Biotinylated IDDM12,ICOS,CD152,GRD4,CTLA4,CELI...	Human	HEK293 Cells
	CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152, is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses.CTLA4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation – a phenomenon which is particularly notable in cancers. It acts as an "off" switch when bound to CD80 or CD86 on the surface of antigen-presenting cells.
TMPY-03589	CTLA4 Protein, Cynomolgus/Rhesus, Recombinant (His) cytotoxic T-lymphocyte-associated protein 4	Cynomolgus,Rhesus	HEK293 Cells
	CTLA4 Protein, Cynomolgus/Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.9 kDa and the accession number is Q9BDC4.
TMPJ-00640	CTLA-4 Protein, Cavia porcellus, Recombinant (His) Cytotoxic T-lymphocyte protein 4,CTLA4...	Cavia porcellus	P. pastoris (Yeast)
	CTLA-4 Protein, Cavia porcellus, Recombinant (His) is expressed in P. pastoris yeast expression system with C-6xHis tag. The predicted molecular weight is 18-40 KDa and the accession number is H0VUB1.
TMPJ-00635	CTLA-4 Protein, Cynomolgus, Recombinant (hFc) Cytotoxic T-lymphocyte-associated antigen 4,Cytotox...	Cynomolgus	HEK293 Cells
	CTLA-4 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 45-60 KDa and the accession number is G7PL88.
TMPJ-00636	CTLA-4 Protein, Cynomolgus, Recombinant (His) Cytotoxic T-lymphocyte protein 4,CTLA-...	Cynomolgus	HEK293 Cells
	CTLA-4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 17-25 KDa and the accession number is G7PL88.
TMPJ-00420	CTLA-4 Protein, Mouse, Recombinant (Flag) Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymph...	Mouse	HEK293 Cells
	Mouse Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule. Within the ECD, Mouse CTLA-4 shares 68% aa sequence identity with human. CTLA4 is similar to the T cell costimulatory protein CD28 since both of the molecules bind to CD80 and CD86 on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found inregulatory T cells and may play an important role in their fu...
TMPJ-00108	CTLA-4 Protein, Human, Recombinant (GST) Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymph...	Human	HEK293 Cells
	CTLA-4 Protein, Human, Recombinant (GST) is expressed in HEK293 mammalian cells with C-GST tag. The predicted molecular weight is 40-55 KDa and the accession number is P16410.
TMPJ-00107	CTLA-4 Protein, Human, Recombinant (Flag) Cytotoxic T-lymphocyte protein 4,CTLA-...	Human	HEK293 Cells
	CTLA-4 Protein, Human, Recombinant (Flag) is expressed in HEK293 mammalian cells with C-Flag tag. The predicted molecular weight is 20 KDa and the accession number is P16410.
TMPY-04348	CTLA-4 Protein, Human, Recombinant (His) ALPS5,CD152,GRD4,cytotoxic T-lymphocyte-associated ...	Human	HEK293 Cells
	CTLA-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is P16410-1.
TMPY-04824	CTLA-4 Protein, Human, Recombinant CTLA-4,GSE,IDDM12,CELIAC3,ALPS5,CD,GRD...	Human	HEK293 Cells
	CTLA-4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.5 kDa and the accession number is P16410-1.
TMPY-06824	CTLA-4 Protein, Human, Recombinant (hFc & Avi), Biotinylated CD152,cytotoxic T-lymphocyte-associated protein 4,G...	Human	HEK293 Cells
	CTLA-4 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 42.89 kDa and the accession number is NP_005205.2.
TMPY-05369	CTLA-4 Protein, Human, Recombinant (hFc), Biotinylated IDDM12,cytotoxic T-lymphocyte-associated protein 4,...	Human	HEK293 Cells
	CTLA-4 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.7 kDa and the accession number is P16410-1.
TMPY-04948	CTLA-4 Protein, Human, Recombinant (His), Biotinylated GSE,ALPS5,GRD4,IDDM12,cytotoxic T-lymphocyte-associ...	Human	HEK293 Cells
	CTLA-4 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is P16410-1.
TMPY-05002	CTLA-4 Protein, Human, Recombinant (hFc) CD,cytotoxic T-lymphocyte-associated protein 4,IDDM...	Human	HEK293 Cells
	CTLA-4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.7 kDa and the accession number is P16410-1.
TMPY-04998	CTLA-4 Protein, Human, Recombinant (rFc) GRD4,CELIAC3,ALPS5,CD,CTLA-4,CD15...	Human	HEK293 Cells
	CTLA-4 Protein, Human, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 39.7 kDa and the accession number is P16410-1.
TMPJ-00129	BTLA Protein, Human, Recombinant (His) B- and T-Lymphocyte-Associated Protein,CD272,BTLA,B- and T-L...	Human	HEK293 Cells
	B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induced during activation of T cells, and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 and CTLA4, BTLA interacts with a B7 homolog, B7H4. However, unlike PD-1 and CTLA-4, BTLA displays T-Cell inhibition via interaction with tumor necrosis family receptors (TNF-R), not just the B7 family of cell surface receptors. BTLA is a ...
TMPJ-00958	B7-1 Protein, Rabbit, Recombinant (His) Activation B7-1 antigen,T-lymphocyte activation antigen CD80...	Rabbit	HEK293 Cells
	Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. Although both CTLA-4 and CD28 can ...
TMPJ-00630	B7-1 Protein, Cynomolgus, Recombinant (hFc) B7,CD80,T-lymphocyte activation antigen CD80,Activation B7-1...	Cynomolgus	HEK293 Cells
	Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells.CD80 plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the ...

重组蛋白

CTLA-4 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00112

Species: Human

Expression System: HEK293 Cells

CTLA4 Protein, Cynomolgus/Rhesus, Recombinant (His)

Cat.No: TMPY-03589

Species: Cynomolgus,Rhesus

Expression System: HEK293 Cells

CTLA-4 Protein, Cavia porcellus, Recombinant (His)

Cat.No: TMPJ-00640

Species: Cavia porcellus

Expression System: P. pastoris (Yeast)

CTLA-4 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPJ-00635

Species: Cynomolgus

Expression System: HEK293 Cells

CTLA-4 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPJ-00636

Species: Cynomolgus

Expression System: HEK293 Cells

CTLA-4 Protein, Mouse, Recombinant (Flag)

Cat.No: TMPJ-00420

Species: Mouse

Expression System: HEK293 Cells

CTLA-4 Protein, Human, Recombinant (GST)

Cat.No: TMPJ-00108

Species: Human

Expression System: HEK293 Cells

CTLA-4 Protein, Human, Recombinant (Flag)

Cat.No: TMPJ-00107

Species: Human

Expression System: HEK293 Cells

CTLA-4 Protein, Human, Recombinant (His)

Cat.No: TMPY-04348

Species: Human

Expression System: HEK293 Cells

CTLA-4 Protein, Human, Recombinant

Cat.No: TMPY-04824

Species: Human

Expression System: HEK293 Cells

CTLA-4 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPY-06824

Species: Human

Expression System: HEK293 Cells

CTLA-4 Protein, Human, Recombinant (hFc), Biotinylated

Cat.No: TMPY-05369

Species: Human

Expression System: HEK293 Cells

CTLA-4 Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-04948

Species: Human

Expression System: HEK293 Cells

CTLA-4 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05002

Species: Human

Expression System: HEK293 Cells

CTLA-4 Protein, Human, Recombinant (rFc)

Cat.No: TMPY-04998

Species: Human

Expression System: HEK293 Cells

BTLA Protein, Human, Recombinant (His)

Cat.No: TMPJ-00129

Species: Human

Expression System: HEK293 Cells

B7-1 Protein, Rabbit, Recombinant (His)

Cat.No: TMPJ-00958

Species: Rabbit

Expression System: HEK293 Cells

B7-1 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPJ-00630

Species: Cynomolgus

Expression System: HEK293 Cells

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