Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2262 |
Itanapraced
CHF5074,CSP-1103 |
Beta Amyloid; Gamma-secretase | Neuroscience; Proteases/Proteasome; Stem Cells |
Itanapraced (CHF5074) 是新型γ-secretase 调节剂,能够降低 Aβ42 (IC50=3.6 nM) 和 Aβ40 (IC50=18.4 nM) 分泌。 | |||
T69061 |
CSP-2503
|
||
CSP-2503 is a 5-HT1A receptor agonist. | |||
T38559 |
Competence-Stimulating Peptide-2 (CSP-2)
|
||
Competence-Stimulating Peptide-2 (CSP-2) is a quorum sensing signal peptide synthesized by Streptococcus pneumoniae. ComD2, a compatible receptor of CSP-2, exhibits an EC 50 value of 50.7 nM. | |||
T39175 |
CSP1
|
||
CSP1 is a highly potent and selective agonist of the ComD1 receptor, exhibiting an IC50 value of 10.3 nM. It represents a major variant of competence-stimulating peptide (CSP) and plays a crucial role in regulating the genetic transformation of S. pneumoniae through modulation of quorum sensing (QS). Additionally, CSP1 possesses antibacterial activity, further enhancing its potential as an effective antibacterial agent. | |||
T8778 |
TTK21
|
Epigenetic Reader Domain | Chromatin/Epigenetic |
TTK21 是 CBP/p300 组蛋白乙酰转移酶活性的激活剂,与葡萄糖基碳纳米球结合时,可通过血脑屏障,对成人大脑神经发生和长期记忆功能有益。 | |||
T63163 | cSPM | ||
cSPM (Cyclic spermine) 是一种 Aβ42 抑制剂。cSPM 对三种不同肽 Aβ42、胰淀素和胰岛素的聚集具有抑制作用,且能够减少细胞毒性。 | |||
T21220 |
3-Chlorodiphenylamine
3-Cl DPA,3-氯二苯胺,3-Cl-DPA,3 Cl-DPA |
||
3-Cl-DPA, a cardiac troponin activator, acts by a mechanism distinct from bepridil or TFP. |