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Cat. No. Product Name Target Signaling Pathways
T3638 Leukadherin-1

Integrin; Complement System Cytoskeletal Signaling; Immunology/Inflammation
Leukadherin-1 是 CD11b/CD18 的变构激活剂,可增加 CD11b/CD18 依赖性细胞对纤维蛋白原的粘附,减少白细胞运动和跨内皮迁移,具有抗炎作用。
T10156 CCR3 antagonist 1

CCR Immunology/Inflammation; Microbiology/Virology
CCR3 antagonist 1是一种有效的 CCR3拮抗药,用于炎症和免疫疾病的研究。
T36654 Anti-SARS-CoV-2 Spike mAb (CR3022)

Anti-SARS-CoV-2 Spike mAb (CR3022)

Anti-SARS-CoV-2 Spike mAb (CR3022) is a human monoclonal IgG1 antibody derived from CHO cells. It specifically targets the S1 domain of the Spike protein in both SARS-CoV and SARS-CoV-2.
T36982 CXCR3 Antagonist 6c

CXCR3 antagonist 6c is an antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3).1It inhibits calcium mobilization induced by chemokine (C-X-C motif) ligand 11 (CXCL11) in HEK293 cells expressing the human receptor (IC50= 0.06 μM). It is selective for CXCR3 over a panel of 14 human G protein-coupled receptors at 10 μM. CXCR3 antagonist 6c inhibits CXCR3-mediated migration of isolated human T cells (IC50= ~100 nM). 1.Cole, A.G., Stroke, I.L., Brescia, M.-R., et al.Identification and initial eva...
T40274 XVA143

XVA143

XVA143, an α/β I-like allosteric antagonist, inhibits LFA-1 dependent firm adhesion, while at the same time it enhances adhesion in shear flow and rolling both in vitro and in vivo. XVA143 is an antagonist of both mouse and human CR3, inhibits the ability of P. gingivalis to persist in the mouse host and cause periodontal bone loss.

化合物

Leukadherin-1
Cat.No: T3638
Synonym:
Target: Integrin, Complement System
CCR3 antagonist 1
Cat.No: T10156
Synonym:
Target: CCR
Anti-SARS-CoV-2 Spike mAb (CR3022)
Cat.No: T36654
Synonym: Anti-SARS-CoV-2 Spike mAb (CR3022)
Target:
CXCR3 Antagonist 6c
Cat.No: T36982
Synonym:
Target:
XVA143
Cat.No: T40274
Synonym: XVA143
Target:
TargetMol Loading
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