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Cat. No. | Product Name | Target | Signaling Pathways |
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T82703 |
CMKLR1 antagonist 1
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CMKLR1 antagonist 1 (compound S-26d) 为口服型趋化因子样受体 1 (CMKLR1) 拮抗剂,其在hCMKLR1感染的CHO细胞中表现出pIC50值达7.44。该化合物适用于银屑病和代谢性疾病的研究。 | |||
T14194 |
β-NETA
α-NETA |
AChE | Neuroscience |
β-NETA(α-NETA) 是胆碱乙酰转移酶(ChA;IC50=76 μM) 和胆碱酯酶 (ChE;IC50=40 µM)的非竞争性抑制剂,对乙酰胆碱酯的作用微弱 (AChE;IC50=1 mM)。 | |||
T37128 |
Chemerin-9, Mouse
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Chemokine-like receptor 1 (CMKLR1) agonist (EC50 = 42 nM). Corresponds to C-terminal of full length mouse Chemerin, amino acids 148 - 156. | |||
T76022 |
Chemerin-9 (149-157) (TFA)
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Chemerin-9 (149-157) TFA 作为趋化因子样受体1 (CMKLR1) 的有效激动剂,展现出抗炎活性,并能促进Akt与ERK磷酸化及活性氧生成,进而改善Aβ1-42诱发的记忆障碍。此外,该化合物还参与调节免疫反应、脂肪细胞分化以及糖代谢。 | |||
T61454 |
α-NETA
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α-NETA是一种有效的胆碱乙酰转移酶(ChA)非竞争性抑制剂,IC50值为9μM。同时,它也是ALDH1A1(IC50=0.04μM)和趋化因子样受体1(CMKLR1)的有效拮抗剂。此外,α-NETA对胆碱酯酶(ChE; IC50=84μM)和乙酰胆碱酯酶(AChE; IC50=300μM)的抑制作用较弱。α-NETA亦显示出抗癌活性。 |
Cat. No. | Product Name | Species | Expression System |
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TMPH-01082 |
CMKLR1 Protein, Human, Recombinant (His)
CMKLR1,G-protein coupled receptor ChemR23,... |
Human | E. coli |
CMKLR1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 45.1 kDa and the accession number is Q99788. | |||
TMPJ-01292 |
Chemerin/RARRES2 Protein, Human, Recombinant (His)
RAR-responsive protein TIG2,RARRES2,Chemerin,Tazarotene-indu... |
Human | HEK293 Cells |
Retinoic acid receptor responder protein 2(RARRES2) is a secreted protein that in humans is encoded by the RARRES2 gene. It is highly expressed in skin, also found in pancreas, liver, spleen, prostate, ovary, small intestine and colon. It is a chemoattractant protein that acts as a ligand for the G protein-coupled receptor CMKLR1. RARRES2 is secreted in an inactive form as prochemerin and is activated through cleavage of the C-terminus by inflammatory and coagulation serine proteases. It is thou... |