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Search Results for " chn "

15

抑制剂 & 化合物

12

天然产物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T38130	Z-LVG-CHN2 Z-Leu-Val-Gly-diazomethylketone
	The diazomethyl ketone Z-LVG-CHN2 mimics part of the human cysteine proteinase-binding center, has been shown to be an irreversible inhibitor of this proteinase. The compound was also tested for antiviral activity against herpes simplex virus type 1 (HSV) and found to block the HSV replication. Irreversible inhibitor of streptopain.
T78119	Z-L(D-Val)G-CHN2	HSV	Microbiology/Virology
	Z-L(D-Val)G-CHN2（即Z-LVG-CHN2）是半胱氨酸蛋白酶抑制剂的异构体，作为一种三肽衍生物，模仿了人体半胱氨酸蛋白酶结合中心的部分结构。它可以抑制HSV，并且能有效阻断SARS-COV-2的3CL pro蛋白酶，从而抑制病毒活性（EC50=190 nM），但对脊髓灰质炎病毒复制无显著作用。
T60554	Schnurri-3 inhibitor-1	Others	Others
	Schnurri-3 inhibitor-1 是有效的 schnurri-3 抑制剂，schnurri-3是成人骨形成的重要调节因子。在成骨细胞系 Shn3FFL 中，Schnurri-3 inhibitor-1 通过 EF1alpha 启动子抑制 Shn3 蛋白表达 (AC50= 2.09 μM)。Schnurri-3 inhibitor-1 可用于骨质疏松症相关的研究。
T35817	Photoswitchable PAD Inhibitor (technical grade)
	Photoswitchable PAD inhibitor is a photoactivated protein arginine deiminase (PAD) inhibitor and a derivative of BB-Cl-amidine that contains an azobenzene photoswitch allowing optical control of PAD activity.1 Without photoactivation, it is a weak inhibitor of PAD2 (IC50 = >100 μM) and is less potent than BB-Cl-amidine in inhibiting citrulline production in vitro (kinact/KIs = 2,300, 600, 1,000, and 10,510 M-1min-1 for PAD1-4, respectively) and does not inhibit histone H3 citrullination in HEK29...
T32836	Lochnericine
	Lochnericine is a alkaloid isolated from elicited cell cultures of Catharanthus roseus.
T32523	Lachnanthocarpone
	Lachnanthocarpone is a member of the 6-oxygenated phenylphenalenones.
T10236	ACHN-975 TFA	Others	Others
	ACHN-975 TFA is a selective LpxC inhibitor with a subnanomolar inhibitory. It is against a wide range of gram-negative bacterias with low MIC values (≤1 μg/mL).
T33021	Lychnopholide
	Lychnopholide is isolated from Vanillosmopsis erythropappa.
T124383	Lychnopholic acid
	Lychnopholic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124383，CAS号为 68945-57-3。
T125032	Strychnistenolide

T32837	Lochneridine
	Lochneridine is a bioactive chemical.
T36108	YW3-56 (hydrochloride) (technical grade) YW3-56 (hydrochloride) (technical grade)
	YW3-56 is an inhibitor of protein arginine deiminase 2 (PAD2) and PAD4 (IC50s = 0.5-1 and 1-5 μM, respectively).1It inhibits the growth of U2OS osteosarcoma cells (IC50= ~2.5 μM) in a p53-dependent mannerviainduction of SESN2 and subsequent inhibition of mTORC1. YW3-56 (10 mg/kg) reduces tumor growth in an S-180 murine sarcoma tumor model. It also inhibits tumor growth in the 1883 MDA-MB-231 breast cancer bone metastasis mouse xenograft model.2 1.Wang, Y., Li, P., Wang, S., et al.Anticancer pept...
T10236L	ACHN-975	Others	Others
	ACHN-975 is a highly potent and selective LpxC inhibitor, demonstrating subnanomolar inhibitory activity. It effectively targets a broad spectrum of gram-negative bacteria, with low minimum inhibitory concentration (MIC) values (≤1 μg/mL)[1].
T62151	CHNQD-01255
	CHNQD-01255 是一种口服具有活力的 Arf-GEFs 抑制剂，能够有效地抵抗肝细胞癌 (HCC)。
T131505	Cyclostachnine
	Cyclostachnine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T131505。

化合物

Cat.No: T38130

Synonym: Z-Leu-Val-Gly-diazomethylketone

Z-L(D-Val)G-CHN2

Cat.No: T78119

Target: HSV

Schnurri-3 inhibitor-1

Cat.No: T60554

Target: Others

Photoswitchable PAD Inhibitor (technical grade)

Cat.No: T35817

Cat.No: T32836

Lachnanthocarpone

Cat.No: T32523

Cat.No: T10236

Target: Others

Cat.No: T33021

Lychnopholic acid

Cat.No: T124383

Strychnistenolide

Cat.No: T125032

Cat.No: T32837

YW3-56 (hydrochloride) (technical grade)

Cat.No: T36108

Synonym: YW3-56 (hydrochloride) (technical grade)

Cat.No: T10236L

Target: Others

Cat.No: T62151

Cat.No: T131505

Cat. No.	Product Name	Target	Signaling Pathways
T80344	Aeschna defensin
	Aeschna defensing是源自蜻蜓水生幼虫血淋巴的抗菌肽，对革兰氏阳性菌具有显著活性。
TN5132	Tetrahydrolachnophyllum lactone	Others	Others
	Tetrahydrolachnophyllum lactone 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5132，CAS号为 56407-87-5。
T82273	Gochnatiolide A
	Gochnatiolide A是从Ainsliaea henryi中提取的一种二聚倍半萜烯，对肾脏、黑色素瘤、卵巢抵抗和神经胶质瘤细胞系显示出抗增殖活性。
TN5494	2'',3''-Dihydroochnaflavone
	2'',3''-Dihydroochnaflavone 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5494，CAS号为 340997-02-6。
T20801	Lochnerine (+)-Lochnerine
	Lochnerine is an alkaloid of terpenoid indole.
TN6262	Boschnaloside
	Boschnaloside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6262，CAS号为 72963-55-4。
T10047	16-Methoxystrychnine	Others	Others
	16-Methoxystrychnine is a alkaloid[1].
TN5803	(Z)-Lachnophyllum lactone
	(Z)-Lachnophyllum lactone 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5803，CAS号为 81122-95-4。
TN1283	4'-O-Methylochnaflavone	Others	Others
	4'-O-Methylochnaflavone is a natural product
T5156	2,3,2'',3''-Tetrahydroochnaflavone 金银花	Others	Others
	2,3,2'',3''-Tetrahydroochnaflavone是一种天然产物，属于忍冬科忍冬属，其产品编号为 T5156，CAS号为 678138-59-5。2,3,2'',3''-Tetrahydroochnaflavone可用作对照参考。
TN5501	Ochnaflavone
	Ochnaflavone 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5501，CAS号为 50276-96-5。
T81963	Lachnone A
	Lachnone A，一种从丝状真菌Lachnum sp. (BCC 2424) 中提取的类黄酮衍生物。

天然产物

Aeschna defensin

Cat.No: T80344

Tetrahydrolachnophyllum lactone

Cat.No: TN5132

Target: Others

Gochnatiolide A

Cat.No: T82273

2'',3''-Dihydroochnaflavone

Cat.No: TN5494

Cat.No: T20801

Synonym: (+)-Lochnerine

Cat.No: TN6262

16-Methoxystrychnine

Cat.No: T10047

Target: Others

(Z)-Lachnophyllum lactone

Cat.No: TN5803

4'-O-Methylochnaflavone

Cat.No: TN1283

Target: Others

2,3,2'',3''-Tetrahydroochnaflavone

Cat.No: T5156

Synonym: 金银花

Target: Others

Cat.No: TN5501

Cat.No: T81963

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03793	CHN1 Protein, Human, Recombinant ARHGAP2,DURS2,RHOGAP2,NC,CHN,chimerin 1	Human	Baculovirus Insect Cells
	CHN1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 53.2 kDa and the accession number is P15882-1.
TMPY-03792	CHN1 Protein, Human, Recombinant (His & GST) NC,chimerin 1,ARHGAP2,RHOGAP2,DURS2,CHN	Human	Baculovirus Insect Cells
	CHN1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 80.9 kDa and the accession number is P15882-1.
TMPH-00315	BUsg_347 Protein, Buchnera aphidicola subsp., Recombinant (His & Myc & SUMO) Porin-like protein BUsg_347	Buchnera aphidicola	E. coli
	Forms pores that allow passive diffusion of small molecules across the membrane. BUsg_347 Protein, Buchnera aphidicola subsp., Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 59.0 kDa and the accession number is Q8K9I8.

重组蛋白

CHN1 Protein, Human, Recombinant

Cat.No: TMPY-03793

Species: Human

Expression System: Baculovirus Insect Cells

CHN1 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-03792

Species: Human

Expression System: Baculovirus Insect Cells

BUsg_347 Protein, Buchnera aphidicola subsp., Recombinant (His & Myc & SUMO)

Cat.No: TMPH-00315

Species: Buchnera aphidicola

Expression System: E. coli

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