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Search Results for " cd95 "

2

抑制剂 & 化合物

12

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T69972	ONL-1204
	ONL-1204 is a small molecule, CD95 antigen inhibitor (Fas inhibitor) being developed by ONL Therapeutics for the treatment of retinal detachment.
T76911	Asunercept
	Asunercept (APG101; CAN008) 是一种靶向CD95L 的可溶性CD95-Fc 融合蛋白。Asunercept 通过选择性地与CD95L 结合，来破坏CD95/CD95L 的信号传导。Asunercept 可用于多形性胶质母细胞瘤 (GBM)、骨髓增生异常综合征 (MDS) 以及移植物抗宿主病 (GvHD) 的研究。

化合物

Cat.No: T69972

Cat.No: T76911

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00799	Fas/CD95 Protein, Human, Recombinant (hFc) CD95,FAS1,ALPS1A,APT1,FASTM,TNFRSF6,APO-1,...	Human	HEK293 Cells
	Fas/CD95 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.4 kDa and the accession number is P25445-1.
TMPJ-00215	Fas/CD95 Protein, Mouse, Recombinant (hFc) CD95,Apoptosis-mediating surface antigen F...	Mouse	HEK293 Cells
	Mouse Apoptosis-mediating surface antigen FAS (Fas) belongs to the death receptor subfamily of the TNF receptor superfamily and is designated TNFRSF6. Mouse Fas contains 1 death domain and 3 TNFR-Cys repeats. It detected in various tissues including thymus, liver, lung, heart, and adult ovary. As a receptor for TNFSF6/FASLG, The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which...
TMPY-03956	Fas Ligand Protein, Human, Recombinant (His) TNLG1A,FASL,FASLG,CD178,CD95-L,AP...	Human	P. pastoris (Yeast)
	Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Fas Ligand Protei...
TMPY-01426	Fas/CD95 Protein, Mouse, Recombinant (His) Fas cell surface death receptor,lpr,CD95,A...	Mouse	HEK293 Cells
	Fas/CD95 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18 kDa and the accession number is P25446.
TMPY-01704	Fas/CD95 Protein, Human, Recombinant (His) TNFRSF6,FAS1,ALPS1A,FASTM,Fas cell surface death receptor,AP...	Human	HEK293 Cells
	Fas/CD95 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.2 kDa and the accession number is P25445-1.
TMPY-04587	Fas Ligand Protein, Mouse, Recombinant (His) CD178,Apt1lg1,Fasl,Cd95l,Faslg,Tn...	Mouse	P. pastoris (Yeast)
	Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Fas Ligand Protei...
TMPY-00632	Fas/CD95 Protein, Cynomolgus, Recombinant Fas cell surface death receptor	Cynomolgus	HEK293 Cells
	Fas/CD95 Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 17.6 kDa and the accession number is F6V1W6.
TMPY-03834	Fas/CD95 Protein, Cynomolgus, Recombinant (hFc) Fas cell surface death receptor	Cynomolgus	HEK293 Cells
	Fas/CD95 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.8 kDa and the accession number is F6V1W6.
TMPY-04282	Fas/CD95 Protein, Rat, Recombinant (hFc) Fas cell surface death receptor	Rat	HEK293 Cells
	Fas/CD95 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.7 kDa and the accession number is A6I127.
TMPY-02057	Fas/CD95 Protein, Rat, Recombinant (His) Fas cell surface death receptor	Rat	HEK293 Cells
	Fas/CD95 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18 kDa and the accession number is A6I127.
TMPY-02213	RAIDD Protein, Human, Recombinant (His) RAIDD,MRT34,CASP2 and RIPK1 domain containing adaptor with d...	Human	E. coli
	Death domain-containing protein CRADD, also known as Caspase and RIP adapter with death domain, RIP-associated protein with a death domain, CRADD and RAIDD, is a protein which is constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney. CRADD / RAIDD contains oneCARD domain and onedeath domain. CRADD / RAIDD contains a death domain involved in the binding of RIP protein. The CARD domain mediates the ...
TMPJ-00226	SLAMF1 Protein, Mouse, Recombinant (His) signaling lymphocytic activation molecule,SLAM family member...	Mouse	HEK293 Cells
	Signaling lymphocyte activation molecule (SLAM), is a self-ligand glycoprotein which exists not only found on the surface of activated and memory T cells, but also on the surface of activated B cells, dendritic cells, and macrophages. SLAM consists of a extracellular domain (ECD) with two Ig-like domains,transmembrane segment, and cytoplasmic domain with three immunoreceptor tyrosine switch motifs (ITSM). SLAM is thought to play an important role in adhesion between T cells and APCs and has been...

重组蛋白

Fas/CD95 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00799

Species: Human

Expression System: HEK293 Cells

Fas/CD95 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00215

Species: Mouse

Expression System: HEK293 Cells

Fas Ligand Protein, Human, Recombinant (His)

Cat.No: TMPY-03956

Species: Human

Expression System: P. pastoris (Yeast)

Fas/CD95 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01426

Species: Mouse

Expression System: HEK293 Cells

Fas/CD95 Protein, Human, Recombinant (His)

Cat.No: TMPY-01704

Species: Human

Expression System: HEK293 Cells

Fas Ligand Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04587

Species: Mouse

Expression System: P. pastoris (Yeast)

Fas/CD95 Protein, Cynomolgus, Recombinant

Cat.No: TMPY-00632

Species: Cynomolgus

Expression System: HEK293 Cells

Fas/CD95 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPY-03834

Species: Cynomolgus

Expression System: HEK293 Cells

Fas/CD95 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-04282

Species: Rat

Expression System: HEK293 Cells

Fas/CD95 Protein, Rat, Recombinant (His)

Cat.No: TMPY-02057

Species: Rat

Expression System: HEK293 Cells

RAIDD Protein, Human, Recombinant (His)

Cat.No: TMPY-02213

Species: Human

Expression System: E. coli

SLAMF1 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00226

Species: Mouse

Expression System: HEK293 Cells

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