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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T76986 | Tarlatamab | ||
Tarlatamab (AMG-757) 是一种双特异性 T 细胞接合剂 (BiTE) 抗体,靶向 delta 样配体 3 (DLL3)。DLL3 是在小细胞肺癌 (SCLC) 肿瘤中选择性表达的靶标,但在正常组织中表达很少。Tarlatamab 对人和非人灵长类动物 (NHP) 的 DLL3 的KD 分别为 0.64 nM 和 0.50 nM,对CD3的KD 分别为 14.9 nM 和 12 nM。Tarlatamab 是针对 DLL3 的一流 HLE BiTE 免疫肿瘤疗法,具有用于 SCLC 研究的潜力。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02501 |
CD3D & CD3E Heterodimer Protein, Human, Recombinant
CD3d molecule, δ (CD3-TC... |
Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-01196 |
CD3D Protein, Human, Recombinant (His)
CD3 δ,CD3 delta... |
Human | HEK293 Cells |
CD3D Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 11 kDa and the accession number is B0YIY4. | |||
TMPY-03745 |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
CD3-DELTA,CD3d ... |
Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-05374 |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His), Biotinylated
T3D,CD3d molecule, δ (CD... |
Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234&P07766. | |||
TMPY-03190 |
CD3D Protein, Human, Recombinant (hFc & FLAG)
CD3-δ,CD3 delta... |
Human | HEK293 Cells |
CD3D Protein, Human, Recombinant (hFc & FLAG) is expressed in HEK293 mammalian cells with hFc and Flag tag. The predicted molecular weight is 37.8 kDa and the accession number is B0YIY4. | |||
TMPY-05243 |
CD3D Protein, Human, Recombinant (hFc & FLAG), Biotinylated
CD3 delta,CD3-δ... |
Human | HEK293 Cells |
CD3D Protein, Human, Recombinant (hFc & FLAG), Biotinylated is expressed in HEK293 mammalian cells with hFc and Flag tag. The predicted molecular weight is 37.8 kDa and the accession number is B0YIY4. | |||
TMPY-06108 |
CD3D & CD3E Heterodimer Protein, Mouse, Recombinant
CD3d molecule, delta (CD... |
Mouse | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 75.4 kDa and the accession number is P04235&P22646. | |||
TMPY-06348 |
CD3D & CD3E Heterodimer Protein, Cynomolgus, Recombinant
CD3d molecule, delta (CD... |
Cynomolgus | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 76.63 kDa and the accession number is Q95LI8-1. | |||
TMPY-03328 |
CD3D & CD3E Heterodimer Protein, Rhesus, Recombinant
CD3d molecule, δ (CD3-TC... |
Rhesus | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Rhesus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 76.7 kDa and the accession number is G7NCB9. | |||
TMPY-06874 |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (His)
CD3d molecule, delta (CD... |
Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.75 kDa. | |||
TMPY-03546 |
CD3D & CD3E Heterodimer Protein, Mouse, Recombinant (Flag & His)
CD3d molecule, δ (CD3-TC... |
Mouse | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Mouse, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 29.2 kDa and the accession number is P04235&P22646. | |||
TMPY-06499 |
CD3D & CD3E Heterodimer Protein, Rhesus, Recombinant (Fc-Flag & Fc-His)
CD3d molecule, delta (CD... |
Rhesus | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Rhesus, Recombinant (Fc-Flag & Fc-His) is expressed in HEK293 mammalian cells with Fc-Flag, Fc-His tag. The predicted molecular weight is 76.63 kDa and the accession number is F6WI60-1. | |||
TMPY-02747 |
CD3D Protein, Cynomolgus, Recombinant (His)
CD3d molecule, δ (CD3-TC... |
Cynomolgus | HEK293 Cells |
CD3D Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 11 kDa and the accession number is Q95LI8. | |||
TMPY-02943 |
CD3D Protein, Cynomolgus, Recombinant (hFc)
CD3d molecule, delta (CD... |
Cynomolgus | HEK293 Cells |
CD3D Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36.6 kDa and the accession number is Q95LI8. | |||
TMPY-04148 |
CD3D Protein, Canine, Recombinant (hFc)
CD3d molecule, δ (CD3-TC... |
Canine | HEK293 Cells |
CD3D Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36.2 kDa and the accession number is A0A8C0PNZ1. | |||
TMPY-03073 |
CD3D Protein, Mouse, Recombinant (hFc)
CD3d molecule, δ (CD3-TC... |
Mouse | HEK293 Cells |
CD3D Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36.4 kDa and the accession number is P04235. | |||
TMPY-02470 |
CD3D & CD3E Heterodimer Protein, Mouse, Recombinant (Fc-Flag & Fc-His)
CD3d molecule, δ (CD3-TC... |
Mouse | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Mouse, Recombinant (Fc-Flag & Fc-His) is expressed in HEK293 mammalian cells with Fc-Flag, Fc-His tag. The predicted molecular weight is 76 kDa and the accession number is P04235&P22646. | |||
TMPJ-01259 |
CD3 epsilon/CD3e Protein, Cynomolgus, Recombinant (aa 22-117, hFc)
CD3 epsilon,T-cell antigen receptor comple... |
Cynomolgus | HEK293 Cells |
T-cell surface glycoprotein CD3 epsilon chain, also known as CD3E, is a single-pass type I membrane protein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. The CD3 epsilon subunit of the T cell receptor (TCR) complex contains two defined signaling domains, a proline-rich sequence and an immune tyrosine activation m... |