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8

抑制剂 & 化合物

8

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T30091	AP-22408 UNII-3U3L5QR4KV,AC1L9I7C,AP22408,CC1
	AP-22408 is an inhibitor of SRC tyrosine kinase.
T60904	ERCC1-XPF-IN-2	Others	Others
	ERCC1-XPF-IN-2 在核苷酸切除修复、顺铂增强和 γH2AX 测定中具有活性。ERCC1-XPF-IN-2 是 ERCC1-XPF 核酸内切酶的有效抑制剂，IC50值为 0.6 μM。
T5845	7ACC1 DEAC,香豆素D1421,Coumarin D 1421,7-(二乙胺基）-2-氧代-2-苯并吡喃-3-羧酸,7-(Diethylamino)coumarin-3-carboxylic acid,D 1421	Monocarboxylate transporter	Membrane transporter/Ion channel
	7ACC1 (D 142) 抑制表达MCT1和MCT4肿瘤细胞的乳酸涌入，能选择性干扰肿瘤微环境乳酸通量。
T24434	MCC1189 MCC 1189,MCC-1189
	MCC1189 is a first-in-class MFS efflux pump CaMdr1p inhibitor.
T61978	ACC1/2-IN-2
	ACC1/2-IN-2 (compound PF-3) 是有效的 ACC1/2抑制剂，IC50分别为 22 和 48 nM。 ACC1/2-IN-2 显示出抗增殖活性，可用于癌症相关研究。
T69496	MCC1019
	MCC1019 is a novel selective inhibitor of the Polo-box domain of Polo-like kinase 1 (PLK1).
T63464	ERCC1-XPF-IN-1
	ERCC1-XPF-IN-1 是有效的、高亲和力的 ERCC1-XPF 抑制剂 (IC50: 0.49 μM)。ERCC1-XPF-IN-1 能够抑制 CPDs 的去除，降低环磷酰胺对结直肠癌细胞的毒性，提高了 UV 辐射的细胞毒性作用，阻碍 DNA 修复。
T63961	ACC1/2-IN-1
	ACC1/2-IN-1 是 ACC1/2 的有效抑制剂，可作用于 ACC1 (IC50: 98.06 nM) 和 ACC2 (IC50: 29.43 nM)。ACC1/2-IN-1 可用于研究癌症。

化合物

Cat.No: T30091

Synonym: UNII-3U3L5QR4KV,AC1L9I7C,AP22408,CC1

Cat.No: T60904

Target: Others

Cat.No: T5845

Synonym: DEAC,香豆素D1421,Coumarin D 1421,7-(二乙胺基）-2-氧代-2-苯并吡喃-3-羧酸,7-(Diethylamino)coumarin-3-carboxylic acid,D 1421

Target: Monocarboxylate transporter

Cat.No: T24434

Synonym: MCC 1189,MCC-1189

Cat.No: T61978

Cat.No: T69496

Cat.No: T63464

Cat.No: T63961

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00205	CEACAM1 Protein, Mouse, Recombinant (hFc) MHVR,MHVR1,Cea-7,mmCGM1a,Cea-1,	Mouse	HEK293 Cells
	CEACAM1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 70.3 kDa and the accession number is Q925P3.
TMPY-01676	CEACAM1 Protein, Mouse, Recombinant (His) Mhv-1,Bgp,mmCGM1a,Hv-2,mmCGM1,Hv2...	Mouse	HEK293 Cells
	CEACAM1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45 kDa and the accession number is Q925P3.
TMPY-02468	CCL14 Protein, Human, Recombinant (aa 28-93, His) MCIF,HCC-3,CC-3,chemokine (C-C motif) liga...	Human	E. coli
	CCL14 Protein, Human, Recombinant (aa 28-93, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 9.3 kDa and the accession number is Q16627-1.
TMPY-02257	CCL14 Protein, Human, Recombinant (His) HCC-3,CKB1,SCYA14,chemokine (C-C ...	Human	E. coli
	CCL14 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 10.2 kDa and the accession number is Q16627-1.
TMPH-03432	ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His) mRNA transport-defective protein 7,Acetyl-CoA carboxylase,Fa...	Saccharomyces cerevisiae	E. coli
	Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which is necessary to maintain a normal morphology of the vacuole. ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His) is expressed in E. coli expression system with N-10xHis tag. The predicted mol...
TMPH-01711	ABCC1 Protein, Human, Recombinant (His) MRP,ATP-binding cassette sub-family C member 1,Leuk...	Human	E. coli
	ABCC1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.9 kDa and the accession number is P33527.
TMPH-02159	SMARCC1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	SMARCC1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 41.5 kDa and the accession number is Q92922.
TMPH-03431	ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His) Acetyl-CoA carboxylase,ACC,Fatty acid synthetase 3,...	Saccharomyces cerevisiae	E. coli
	Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which is necessary to maintain a normal morphology of the vacuole. ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His) is expressed in E. coli expression system with N-10xHis tag. The predicted m...

重组蛋白

CEACAM1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-00205

Species: Mouse

Expression System: HEK293 Cells

CEACAM1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01676

Species: Mouse

Expression System: HEK293 Cells

CCL14 Protein, Human, Recombinant (aa 28-93, His)

Cat.No: TMPY-02468

Species: Human

Expression System: E. coli

CCL14 Protein, Human, Recombinant (His)

Cat.No: TMPY-02257

Species: Human

Expression System: E. coli

ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His)

Cat.No: TMPH-03432

Species: Saccharomyces cerevisiae

Expression System: E. coli

ABCC1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01711

Species: Human

Expression System: E. coli

SMARCC1 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02159

Species: Human

Expression System: E. coli

ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His)

Cat.No: TMPH-03431

Species: Saccharomyces cerevisiae

Expression System: E. coli

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