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代谢 微生物学 神经科学 NF-κB信号通路 氧化还原 PI3K/Akt/mTOR信号通路 蛋白酶体
干细胞 蛋白酪氨酸激酶 泛素化 PROTAC 其他
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类药性化合物库 多样性核心库Part2 多样性核心库Part1 药物靶点库 多样性核心预制库 Golden骨架库 Mini骨架库 化合物库深度定制
TargetMol Compound Library
天然产物库 高通量筛选天然产物库 特色天然产物库 天然产物衍生物库 虚拟筛选天然产物库
结构类型 萜类 类固醇 类黄酮 醌类 香豆素 木脂素 多糖和糖苷
苯丙烷 生物碱 酚类 其他
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基于表型筛选实体化合物活性筛选 细胞增殖检测 细胞周期检测 细胞凋亡检测 药代动力学研究
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细胞因子和生长因子 •   细胞因子 •   生长因子 受体蛋白 •   Fc 受体 •   细胞因子和生长因子受体
CD 蛋白 •   T 细胞 CD 蛋白 •   B 细胞 CD 蛋白 免疫检查点蛋白 •   抑制性免疫检查点蛋白 •   刺激性免疫检查点蛋白
CAR-T 细胞治疗靶点蛋白 •   血液恶性肿瘤靶点蛋白 •   实体瘤靶点蛋白 酶 •   氧化还原酶 •   转移酶
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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T80277 CaLL

CaLL为具抗菌活性的抗菌肽，针对B. anthracis, B. anthracis (vegetative), and B. cepacia表现出MIC为7.8、31.3、31.3 μg/mL的效力。
T78572 Ecallantide

DX-88
Ecallantide (DX-88) 是高特异性重组血浆激肽释放酶抑制剂，用于阻断缓激肽生成，治疗血管性水肿急性发作。
T124920 Calliterpenone

Calliterpenone 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124920，CAS号为 38602-53-8。
T124769 3-O-Acetylcalliterpenone

3-O-Acetylcalliterpenone 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124769，CAS号为 49816-65-1。
T82510 Ecallantide TFA

DX-88 TFA
Ecallantide (DX-88) TFA 是一种特异性的重组血浆激肽释放酶(Kallikrein)抑制剂，作用于缓激肽的生成过程以减少其产生。此化合物主要用于预防和治疗血管性水肿的急性攻击。
T37576 Callosobruchusic Acid

Callosobruchusic acid is an insect pheromone and monoterpene that has been found as a component of the copulation release pheromone erectin in azuki bean weevils (C. chinensis).1It induces copulation release activity in male azuki bean weevils (EC50= 6.5 ng/insect). 1.Mori, K., Ito, T., Tanaka, K., et al.Synthesis and biological activity of optically active forms of (E)-3, 7-dimethyl-2-octene-1, 8-dioic acid (callosobruchusic acid): A component of the copulation release pheromone (erectin) of th...
T77943 SJ1008030 TFA

JAK; PROTACs Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; PROTAC; Stem Cells
SJ1008030 TFA（化合物8）是一种针对JAK2的PROTAC，能够选择性地降解JAK2蛋白。该化合物在抑制MHH-CALL-4细胞系增殖方面表现出显著效能，其IC50值为5.4 nM。SJ1008030 TFA主要应用于白血病相关研究。
T34911 TPT-172 HCl (R33)

TPT 172,TPT172,TPT-172,thiophene thiourea derivative. R33
TPT-172, also known as R33 (described in Mecozzi et al' s paper), is a thiophene thiourea derivative with molecule weight 172 in free base form. There is no formal name yet, we temporally call this molecule as TPT-172. Please also see similar products: TP
T77944 SJ1008030 formic

PROTACs PROTAC
SJ1008030 formic（化合物8）是一款针对JAK2的PROTAC，能够选择性地降解JAK2。该化合物在抑制MHH-CALL-4细胞系增殖方面表现出5.4 nM的IC50值，适用于白血病的研究。
T71344 G-479

G-479 is an potent MEK inhibitor. Structurally, G-479 is an analogue of GDC-0623 (or so-call Me-Too drug). G-479 with polarity distributed throughout the molecule was shown improved bioactivity over GDC-0623 in many aspects.
T34189 PTZ-256

phenothiazine derivative,PTZ256
PTZ-256 is a phenothiazine derivative with chemical name: 3-(10H-phenothiazin-10-yl)propane-1-amine. PTZ-256 has molecule weight 256, therefore, we call it as PTZ-256.
T34912 TPT197 HCl

TPT 197,TPT197
TPT-197 is a thiophene thiourea derivative with molecule weight 197 in free base form. There is no formal name yet, we temporally call this molecule as TPT-197. Please also see similar products: TPT-197; TPT-260; TPT-172.
T74580 SJ1008030

SJ1008030 (compound 8) 是一种JAK2PROTAC 选择性地降解JAK2。SJ1008030 对 MHH–CALL-4 细胞系的EC50值为 5.4 nM，IC50值为 32.09 nM。SJ1008030 可用于白血病的研究。

化合物

CaLL
Cat.No: T80277
Synonym:
Target:
Ecallantide
Cat.No: T78572
Synonym: DX-88
Target:
Calliterpenone
Cat.No: T124920
Synonym:
Target:
3-O-Acetylcalliterpenone
Cat.No: T124769
Synonym:
Target:
Ecallantide TFA
Cat.No: T82510
Synonym: DX-88 TFA
Target:
Callosobruchusic Acid
Cat.No: T37576
Synonym:
Target:
SJ1008030 TFA
Cat.No: T77943
Synonym:
Target: JAK, PROTACs
TPT-172 HCl (R33)
Cat.No: T34911
Synonym: TPT 172,TPT172,TPT-172,thiophene thiourea derivative. R33
Target:
SJ1008030 formic
Cat.No: T77944
Synonym:
Target: PROTACs
G-479
Cat.No: T71344
Synonym:
Target:
PTZ-256
Cat.No: T34189
Synonym: phenothiazine derivative,PTZ256
Target:
TPT197 HCl
Cat.No: T34912
Synonym: TPT 197,TPT197
Target:
SJ1008030
Cat.No: T74580
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TN1006 Tirucallol

NOS; NO Synthase; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Tirucallol 是一种四环三萜，分离自Euphorbia lacteal 乳胶。它能够抑制小鼠模型中的耳部水肿，并阻碍脂多糖刺激的巨噬细胞中亚硝酸盐的产生，具有局部消炎作用。
TN2979 3-Oxotirucalla-7,24-dien-21-oic acid

Others Others
3-Oxotirucalla-7,24-dien-21-oic acid 是首次从蓼属植物中分离得到的已知化合物，可从黑参根中分离得到。3-Oxotirucalla-7,24-dien-21-oic acid 对 MCF-7细胞系显示出强大的细胞毒性。
TN6146 Callosin

Callosin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6146，CAS号为 166197-43-9。
TN2457 3α-acetoxy-tirucall-7,24-dien-21oic acid

Others Others
3α-acetoxy-tirucall-7,24-dien-21oic acid is a natural product from Boswellia carterii Birdw
TN2819 24,25-Epoxytirucall-7-en-3,23-dione

Others Others
24,25-Epoxytirucall-7-en-3,23-dione 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2819，CAS号为 890928-81-1。
TN2978 3-Oxo-24,25,26,27-tetranortirucall-7-en-23,21-olide

Others Others
3-Oxo-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone shows significant inhibitory activities against human cancer cell lines in vitro.
TN5182 Triptocallic acid D

Others Others
Triptocallic acid D 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5182，CAS号为 201534-09-0。
TN5183 Triptocalline A

Others Others
Triptocalline A shows an inhibitory effect on rat lens aldose reductase.
T13501 3-Oxo-21α-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone

3-oxo-21-alpha-methoxy-24-25-26-27-tetranortirucall-7-ene-23-21-lactone

 Others Others
The compound 3-Oxo-21α-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone is a cytotoxic tirucallane C26 triterpenoid that has been extracted from the stem barks of Aphanamixis grandifolia.
TN5181 Triptocallic acid A

Others Others
Triptocallic acid A 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5181，CAS号为 190906-61-7。
TN2804 21,23:24,25-Diepoxy-21,23-dimethoxytirucall-7-en-3-one

Others Others
21,23:24,25-Diepoxy-21,23-dimethoxytirucall-7-en-3-one 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2804，CAS号为 1351617-74-7。
TN2448 3α-Hydroxy tirucall-7,24-dien-21-oic acid

Others Others
3α-Hydroxy tirucall-7,24-dien-21-oic acid is a natural product from Boswellia carterii Birdw
TN2889 3,4-Secotirucalla-4(28,7,24-triene-3),26-dioic acid

Others Others
3,4-Secotirucalla-4(28,7,24-triene-3),26-dioic acid是一种天然产物，属于杨梅科杨梅属，其产品编号为 TN2889，CAS号为 159623-48-0。3,4-Secotirucalla-4(28,7,24-triene-3),26-dioic acid可用作对照参考。

天然产物

Tirucallol
Cat.No: TN1006
Synonym:
Target: NOS, NO Synthase, Prostaglandin Receptor
3-Oxotirucalla-7,24-dien-21-oic acid
Cat.No: TN2979
Synonym:
Target: Others
Callosin
Cat.No: TN6146
Synonym:
Target:
3α-acetoxy-tirucall-7,24-dien-21oic acid
Cat.No: TN2457
Synonym:
Target: Others
24,25-Epoxytirucall-7-en-3,23-dione
Cat.No: TN2819
Synonym:
Target: Others
3-Oxo-24,25,26,27-tetranortirucall-7-en-23,21-olide
Cat.No: TN2978
Synonym:
Target: Others
Triptocallic acid D
Cat.No: TN5182
Synonym:
Target: Others
Triptocalline A
Cat.No: TN5183
Synonym:
Target: Others
3-Oxo-21α-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone
Cat.No: T13501
Synonym: 3-oxo-21-alpha-methoxy-24-25-26-27-tetranortirucall-7-ene-23-21-lactone
Target: Others
Triptocallic acid A
Cat.No: TN5181
Synonym:
Target: Others
21,23:24,25-Diepoxy-21,23-dimethoxytirucall-7-en-3-one
Cat.No: TN2804
Synonym:
Target: Others
3α-Hydroxy tirucall-7,24-dien-21-oic acid
Cat.No: TN2448
Synonym:
Target: Others
3,4-Secotirucalla-4(28,7,24-triene-3),26-dioic acid
Cat.No: TN2889
Synonym:
Target: Others
Species：
Calloselasma rhodostoma (5)
Mouse (4)
Human (3)
Gadus callarias (1)
Expression System：
HEK293 Cells (7)
E. coli (3)
P. pastoris (Yeast) (3)
Tag：
C-His (4)
N-6xHis (4)
C-hFc (2)
N-10xHis, C-Myc (1)
N-6xHis-SUMO (1)
Tag Free (1)
Cat. No. Product Name Species Expression System
TMPK-00811 L1CAM Protein, Mouse, Recombinant (His)

CALL,MGC132578,FLJ44930,NCAM-L1,MIC5,CHL-1,SPG1,HSA...

 Mouse HEK293 Cells
L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system. Subsequent work discovered that L1CAM is expressed in many human cancers and is often associated with bad prognosis. This is most likely due to the motility and invasion promoting function of L1CAM. L1CAM is a valuable diagnostic/prognostic marker and an attractive target for the therapy of several human cancers.
TMPY-01688 CHL1 Protein, Human, Recombinant (His)

L1CAM2,cell adhesion molecule L1-like,CALL,LICAM2

 Human HEK293 Cells
CHL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 120 kDa and the accession number is AAI04919.1.
TMPY-03819 CHL1 Protein, Mouse, Recombinant (hFc)

A530023M13Rik,AI465420,cell adhesion molecule L1-like,CA...

 Mouse HEK293 Cells
CHL1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 139.4 kDa.
TMPY-03770 CHL1 Protein, Mouse, Recombinant (His)

cell adhesion molecule L1-like,A530023M13Rik,CALL,A...

 Mouse HEK293 Cells
CHL1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 113.9 kDa and the accession number is XP_017176866.1.
TMPY-04063 CHL1 Protein, Mouse, Recombinant

A530023M13Rik,LICAM2,AI465420,cell adhesion molecule L1-like...

 Mouse HEK293 Cells
CHL1 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 113.3 kDa.
TMPH-00322 Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His)

Calloselasma rhodostoma P. pastoris (Yeast)
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLCgamma2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostom...
TMPH-00321 Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His & SUMO)

Calloselasma rhodostoma E. coli
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodo...
TMPH-00324 SVTLE Protein, Calloselasma rhodostoma, Recombinant (His)

Calloselasma rhodostoma P. pastoris (Yeast)
SVTLE Protein, Calloselasma rhodostoma, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 28.6 kDa and the accession number is P26324.
TMPH-00320 Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His)

Calloselasma rhodostoma P. pastoris (Yeast)
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodo...
TMPH-00323 Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His & Myc)

Calloselasma rhodostoma E. coli
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLCgamma2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostom...
TMPH-00763 Parvalbumin beta Protein, Gadus morhua subsp. callarias, Recombinant (His)

Gadus callarias E. coli
In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. Parvalbumin beta Protein, Gadus morhua subsp. callarias, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.1 kDa and the accession number is P02622.
TMPY-02889 IZUMO4 Protein, Human, Recombinant (hFc)

C19orf36,IMAGE:4215339,IZUMO family member 4,UNQ831/PRO1758

 Human HEK293 Cells
Izumo is a sperm membrane protein that plays a key role in the fusion in the mouse. It has an Immunoglobulin (Ig) domain and an N-terminal domain for which neither the functions nor homologous sequences are known. Up to now, there four members has an N-terminal domain with significant homology to the N-terminal domain of Izumo. We call this domain the Izumo domain. The four proteins are Izumo 1, 2, 3, and 4. Izumo domain possesses the ability to form dimers, whereas the transmembrane domain or t...
TMPY-03220 IZUMO1 Protein, Human, Recombinant (His)

izumo sperm-egg fusion 1,IZUMO

 Human HEK293 Cells
Izumo is a sperm membrane protein that plays a key role in the fusion in the mouse. It has an Immunoglobulin (Ig) domain and an N-terminal domain for which neither the functions nor homologous sequences are known. Up to now, there four members has an N-terminal domain with significant homology to the N-terminal domain of Izumo. We call this domain the Izumo domain. The four proteins are Izumo 1, 2, 3, and 4. Izumo domain possesses the ability to form dimers, whereas the transmembrane domain or t...

重组蛋白

L1CAM Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00811
Species: Mouse
Expression System: HEK293 Cells
CHL1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01688
Species: Human
Expression System: HEK293 Cells
CHL1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-03819
Species: Mouse
Expression System: HEK293 Cells
CHL1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-03770
Species: Mouse
Expression System: HEK293 Cells
CHL1 Protein, Mouse, Recombinant
Cat.No: TMPY-04063
Species: Mouse
Expression System: HEK293 Cells
Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His)
Cat.No: TMPH-00322
Species: Calloselasma rhodostoma
Expression System: P. pastoris (Yeast)
Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His & SUMO)
Cat.No: TMPH-00321
Species: Calloselasma rhodostoma
Expression System: E. coli
SVTLE Protein, Calloselasma rhodostoma, Recombinant (His)
Cat.No: TMPH-00324
Species: Calloselasma rhodostoma
Expression System: P. pastoris (Yeast)
Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His)
Cat.No: TMPH-00320
Species: Calloselasma rhodostoma
Expression System: P. pastoris (Yeast)
Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His & Myc)
Cat.No: TMPH-00323
Species: Calloselasma rhodostoma
Expression System: E. coli
Parvalbumin beta Protein, Gadus morhua subsp. callarias, Recombinant (His)
Cat.No: TMPH-00763
Species: Gadus callarias
Expression System: E. coli
IZUMO4 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02889
Species: Human
Expression System: HEK293 Cells
IZUMO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03220
Species: Human
Expression System: HEK293 Cells
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