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Cat. No. Product Name Target Signaling Pathways
T18485 NH2-C4-NH-Boc

N-叔丁氧羰基-1,4-丁二胺

Others; PROTAC Linker Others; PROTAC
NH2-C4-NH-Boc 是一种属于 Alkyl/ether 类的 PROTAC linker,可用于一系列 PROTAC 分子的合成。
T36841 IPI-9119

Fatty Acid Synthase Metabolism
IPI-9119 是一种具有口服活性、选择性和不可逆的 FASN 抑制剂 (IC50 = 0.3 nM)。
T14584 Biotin-PEG2-C4-alkyne

Others Others
Biotin-PEG2-C4-alkyne is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18624 NH2-Ph-C4-acid-NH2-Me

PROTAC Linker 31

Others Others
NH2-Ph-C4-acid-NH2-Me (PROTAC Linker 31) is an alkyl chain-based compound utilized for the synthesis of PROTACs. [1]
T18623 Boc-NH-PEG2-C2-amido-C4-acid

PROTAC Linker 30

Others Others
Boc-NH-PEG2-C2-amido-C4-acid (PROTAC Linker 30) is a polyethylene glycol (PEG)-based linker utilized for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
T17910 (S,R,S)-AHPC-PEG2-C4-Cl

E3 ligase Ligand-Linker Conjugates 10,VHL Ligand-Linker Conjugates 7,VH032-PEG2-C4-Cl

Others Others
(S,R,S)-AHPC-PEG2-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-PEG2-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
T27601 IMTPPE

SID-3712502,SID 3712502,SID3712502

IMTPPE inhibits transcriptional activity and protein level of AR in C4-2 prostate cancer cells. It also inhibits AR-target gene expression.
T18533 PEG3-C4-OBn

Others Others
PEG3-C4-OBn, a polyethylene glycol (PEG)-based PROTAC linker, is utilized in crafting the PROTAC SGK3 degrader-1, a potent SKG3 degrader leveraging PROTAC technology [1][2].
T37564 C4 Ceramide (d18:1/4:0)

C4 Ceramide (d18:1/4:0),Cer(d18:1/4:0)

C4 Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. [1] [2] [3] It inhibits IL-4 production by 16% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. [1] C4 Ceramide is cytotoxic to SK-BR-3 and MCF-7/Adr breast cancer cells (IC50s = 15.9 and 19.9 μM, respectively). [2] C4 Ceramide also increases maturation and stability of cystic fibrosis transmembrane conductance regulator (CFTR) proteins bearing...
T62031 SARS-CoV-2 nsp13-IN-4

SARS-CoV-2 nsp13-IN -4 (C4 (d)) 是强效的、选择性的 nsp13 helicase 小分子抑制剂。SARS-CoV-2 nsp13-IN -4 抑制 nsp13 的 ssDNA+ ATPase 活性,IC50值为57 μM。SARS-CoV-2 nsp13-IN-4 显示广谱抗病毒作用。
T17906 Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc

E3 Ligase Ligand-Linker Conjugates 53,Cereblon Ligand-Linker Conjugates 20

Others Others
Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc is a novel synthesized conjugate compound functioning as an E3 ligase ligand-linker in PROTAC technology. This compound incorporates a Pomalidomide-derived cereblon ligand, which binds selectively to the E3 ligase cereblon, and a 2-unit PEG linker, which provides stability and flexibility to the conjugate.
T37506 MCTR2

MCTR2

Maresin conjugates in tissue regeneration 2 (MCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages at the site of inflammation. DHA is oxidized to maresin 1 , which is converted to MCTR1 by glutathione S-transferase Mu 4 or leukotriene C4 synthase then to MCTR2 by γ-glutamyl transferase. MCTR2 accelerates tissue regeneration in planaria (1 and 100 nM). Pretreatment with MCTR2 prior to E. coli administration reduces neutrophil infiltration, shor...
T35790 Palmitic acid-1,2,3,4-13C4

Palmitic Acid-13C (C1, C2, C3, and C4 labeled)

Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellula...
T37736 N-cis-hexadec-9Z-enoyl-L-Homoserine lactone

N-(2-oxotetrahydrofuran-3S-yl) Palmitoleyl Amide,N-cis-hexadec-9Z-enoyl-L-Homoserine lactone

Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.[2] Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of whic...
T37741 N-hexadecanoyl-L-Homoserine lactone

C16-HSL,N-palmitoyl-L-Homoserine,N-hexadecanoyl-L-Homoserine lactone

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.[2] Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which...

化合物

NH2-C4-NH-Boc
Cat.No: T18485
Synonym: N-叔丁氧羰基-1,4-丁二胺
Target: Others, PROTAC Linker
IPI-9119
Cat.No: T36841
Synonym:
Target: Fatty Acid Synthase
Biotin-PEG2-C4-alkyne
Cat.No: T14584
Synonym:
Target: Others
NH2-Ph-C4-acid-NH2-Me
Cat.No: T18624
Synonym: PROTAC Linker 31
Target: Others
Boc-NH-PEG2-C2-amido-C4-acid
Cat.No: T18623
Synonym: PROTAC Linker 30
Target: Others
(S,R,S)-AHPC-PEG2-C4-Cl
Cat.No: T17910
Synonym: E3 ligase Ligand-Linker Conjugates 10,VHL Ligand-Linker Conjugates 7,VH032-PEG2-C4-Cl
Target: Others
IMTPPE
Cat.No: T27601
Synonym: SID-3712502,SID 3712502,SID3712502
Target:
PEG3-C4-OBn
Cat.No: T18533
Synonym:
Target: Others
C4 Ceramide (d18:1/4:0)
Cat.No: T37564
Synonym: C4 Ceramide (d18:1/4:0),Cer(d18:1/4:0)
Target:
SARS-CoV-2 nsp13-IN-4
Cat.No: T62031
Synonym:
Target:
Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc
Cat.No: T17906
Synonym: E3 Ligase Ligand-Linker Conjugates 53,Cereblon Ligand-Linker Conjugates 20
Target: Others
MCTR2
Cat.No: T37506
Synonym: MCTR2
Target:
Palmitic acid-1,2,3,4-13C4
Cat.No: T35790
Synonym: Palmitic Acid-13C (C1, C2, C3, and C4 labeled)
Target:
N-cis-hexadec-9Z-enoyl-L-Homoserine lactone
Cat.No: T37736
Synonym: N-(2-oxotetrahydrofuran-3S-yl) Palmitoleyl Amide,N-cis-hexadec-9Z-enoyl-L-Homoserine lactone
Target:
N-hexadecanoyl-L-Homoserine lactone
Cat.No: T37741
Synonym: C16-HSL,N-palmitoyl-L-Homoserine,N-hexadecanoyl-L-Homoserine lactone
Target:
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