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Cat. No.	Product Name	Target	Signaling Pathways
T9905	Cetuximab Cetuximab (anti-EGFR),C225,西妥昔单抗	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Cetuximab (C225) 属于单克隆抗体，是一种人源表皮生长因子受体 (EGFR) 的抑制剂 (Kd=0.201 nM)。Cetuximab 具有抗肿瘤活性，可以抑制肿瘤细胞增殖，诱导细胞凋亡。
T21128	Lansoprazole sulfide Lansoprazole impurity C,AG-1777,EC 600-451-9,H 225/18,K-1252
	Lansoprazole sulfide is an impurity of Lansoprazole, which is a gastric pump inhibitor.
T36944	Ara-G	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Ara-G 是一种脱氧鸟苷 (GdR) 类似物和核苷类似物，可被 T 淋巴谱系细胞迅速转化为其相应的阿拉伯糖基鸟嘌呤核苷酸三磷酸 (araGTP)，从而抑制 DNA 合成和对 T 淋巴母细胞的选择性体外毒性细胞系以及来自 T 细胞急性淋巴细胞白血病 (ALL) 患者的新鲜分离的白血病细胞。
T36414	N-Nitroso Sarcosine
	N-Nitroso sarcosine is a carcinogen and nitrosation product of sarcosine that has been found in cured meat products.1,2In vivo, N-nitroso sarcosine (225 mg/kg) induces the formation of metastatic liver carcinomas in mice.2 1.Janzowski, C., Eisenbrand, G., and Preussmann, R.Occurrence of N-nitrosamino acids in cured meat products and their efffect on formation of N-nitrosamines during heatingFood Cosmet. Toxicol.16(4)343-348(1978) 2.Wogan, G.N., Paglialunga, S., Archer, M.C., et al.Carcinogenicit...
T38269	Purfalcamine
	Purfalcamine is an orally active, selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor with an IC50 of 17 nM and an EC50 of 230 nM. Purfalcamine has antimalarial activity and causes malaria parasites developmental arrest at the schizont stage[1][2]. Purfalcamine has low activity against Toxoplasma gondii calcium-dependent protein kinase 3 (TgCDPK3)[1]. Purfalcamine (225, 450 nM) has no effect on the parasitemia in the first 32 hours. After about 40 hours, paras...

化合物

Cat.No: T9905

Synonym: Cetuximab (anti-EGFR),C225,西妥昔单抗

Target: EGFR

Lansoprazole sulfide

Cat.No: T21128

Synonym: Lansoprazole impurity C,AG-1777,EC 600-451-9,H 225/18,K-1252

Cat.No: T36944

Target: Nucleoside Antimetabolite/Analog

N-Nitroso Sarcosine

Cat.No: T36414

Cat.No: T38269

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