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Targets Recommended: PARP

3

抑制剂 & 化合物

1

天然产物

3

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T7896 BYK204165

RT-017290

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
BYK204165 (RT-017290) 是一种选择性PARP1抑制剂,对重组人 PARP1的pIC50值为 7.35,pKi 值为7.05。它对鼠 PARP-2的pIC50值为 5.38 ,其对 PARP1 的选择性比对 PARP2 高 100 倍。
T1024 Roflumilast

罗氟司特,B9302-107,BYK 20869,APTA 2217,BY 217

PDE; RSV Metabolism; Microbiology/Virology
Roflumilast (APTA 2217) 是一种口服的长效 4 型磷酸二酯酶抑制剂 (PDE4),具有抗炎和潜在的抗肿瘤活性,作用于PDE4A1,PDEA4,PDEB1和PDEB2,IC50分别为 0.7,0.9,0.7 和 0.2 nM。
T12977 Soraprazan

BYK61359

Others Others
Soraprazan is a reversible, and fast-acting gastric H+/K+ ATPase inhibitor.

化合物

BYK204165
Cat.No: T7896
Synonym: RT-017290
Target: PARP
Roflumilast
Cat.No: T1024
Synonym: 罗氟司特,B9302-107,BYK 20869,APTA 2217,BY 217
Target: PDE, RSV
Soraprazan
Cat.No: T12977
Synonym: BYK61359
Target: Others
Cat. No. Product Name Target Signaling Pathways
T40878 Bombykol

Hexadeca-10E,12Z-dien-1-ol,蚕蛾醇,(10E,12Z)-hexadeca-10,12-dien-1-ol,10E,12Z-hexadecadien-1-ol,Isobombycol

Others Others
Bombykol (Isobombycol) 是一种昆虫性信息素,是为 Bombyx mori 的雌性生产的性吸引剂。

天然产物

Bombykol
Cat.No: T40878
Synonym: Hexadeca-10E,12Z-dien-1-ol,蚕蛾醇,(10E,12Z)-hexadeca-10,12-dien-1-ol,10E,12Z-hexadecadien-1-ol,Isobombycol
Target: Others
Cat. No. Product Name Species Expression System
TMPK-00901 TYRO3 Protein, Mouse, Recombinant (His)

BYK,TYRO3,Brt,Rse,TIF,DTK,SKY

Mouse HEK293 Cells
TYRO3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 43 kDa and the accession number is P55144-2.
TMPK-00533 TYRO3 Protein, Cynomolgus, Recombinant (His)

TIF,DTK,Rse,Brt,TYRO3,SKY,BYK

Cynomolgus HEK293 Cells
TYRO3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 42.47 kDa and the accession number is A0A2K5WCY8.
TMPJ-01081 Dtk Protein, Human, Recombinant (His)

RSE,SKY,DTK,Tyrosine-protein kinase DTK,Tyrosine-protein kin...

Human HEK293 Cells
Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken cEyk)constitute a new receptor tyrosine kinase subfamily. The extracellular domain of these proteins contain two Ig-like motifs and two fibronectin type III motifs. This characteristic topology is also found in neural cell adhesion molecules and in receptor tyrosine phosphatases. All three receptors bind the vitamin K-dependent protein growth-arrest specific gene 6 (Gas6) which is structurally related to th...

重组蛋白

TYRO3 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00901
Species: Mouse
Expression System: HEK293 Cells
TYRO3 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00533
Species: Cynomolgus
Expression System: HEK293 Cells
Dtk Protein, Human, Recombinant (His)
Cat.No: TMPJ-01081
Species: Human
Expression System: HEK293 Cells
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