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Cat. No.	Product Name	Target	Signaling Pathways
T17258	WRG-28	Discoidin Domain Receptor (DDR)	Tyrosine Kinase/Adaptors
	WRG-28 是一种选择性的、细胞外作用的DDR2变构抑制剂 (IC50:230 nM)。它通过受体的变构调节特异地抑制受体-配体相互作用。它通过靶向 DDR2 抑制肿瘤侵袭和迁移，基质的肿瘤支持作用，能够抑制肺中的转移性乳腺肿瘤细胞定植。
T13224	Tubulin inhibitor 6 iHAP1	Microtubule Associated	Cytoskeletal Signaling
	Tubulin inhibitor 6 (iHAP1) 是一种微管蛋白抑制剂，抑制微管蛋白聚合，IC50为 0.87 μM。它抑制多种癌细胞系，抑制 K562 细胞生长，IC50为 840 nM。
T4459	PK11000	DNA Alkylator/Crosslinker	DNA Damage/DNA Repair
	PK11000 是一种烷化剂，可通过共价半胱氨酸修饰来稳定野生型和突变型p53的 DNA 结合结构域。
T35732	Diacetylcercosporin
	Diacetylcercosporin is a perylenequinone produced by Cercospora and Septoria that has diverse biological activities. It inhibits the growth of P. falciparum strains that are sensitive and resistant to chloroquine and L. donovani parasites (IC50 = 3.1 μM) in vitro. Diacetylcercosporin exhibits cytotoxicity against SK-MEL, KB, BT549, and SK-OV-3 human cancer cell lines (IC50s = 4.8-8.7 μM). It is also a phytotoxin that inhibits the growth of lettuce and bentgrass at a concentration of 1.62 mM
T36868	4-oxo Docosahexaenoic Acid
	4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of DHA with antiproliferative and PPARγ agonist activity. It inhibits the growth of several triple negative breast cancer cell lines (MCF-10F, trMCF, bsMCF, MDA-MB-231, and BT549) at 50-100 μM, however it increased proliferation of MCF-7 cells. 4-oxo DHA binds covalently to PPARγ and activates gene transcription in luciferase reporter assays and in dendritic cells with EC50 values of approximately 8-16 μM.
T13226	Tubulin inhibitor 8	Microtubule Associated	Cytoskeletal Signaling
	Tubulin inhibitor 8是管蛋白和多种癌症细胞系的抑制剂，对管蛋白聚合和K562细胞生长具有抑制作用，IC50分别为0.73μM 和14nM。

化合物

Cat.No: T17258

Target: Discoidin Domain Receptor (DDR)

Tubulin inhibitor 6

Cat.No: T13224

Synonym: iHAP1

Target: Microtubule Associated

Cat.No: T4459

Target: DNA Alkylator/Crosslinker

Diacetylcercosporin

Cat.No: T35732

4-oxo Docosahexaenoic Acid

Cat.No: T36868

Tubulin inhibitor 8

Cat.No: T13226

Target: Microtubule Associated

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