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Cat. No. Product Name Target Signaling Pathways
T22136 PRL-3 Inhibitor I

PRL-3 Inhibitor,BR-1

Phosphatase; Others Metabolism; Others
PRL-3 Inhibitor I (BR-1) 是 PRL-3 抑制剂,IC50=0.9 μM。它在细胞检测中显示降低侵袭性。
T9855 BR10291

4-Thiazolecarboxamide, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-2-[(3,4-dichlorophenyl)methyl]-

Others Others
BR102910 (4-Thiazolecarboxamide, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-2-[(3,4-dichlorophenyl)methyl]-) 是一种选择性的成纤维细胞活化蛋白(FAP)的抑制剂。
T7156 NIBR189

EBI2/GPR183 GPCR/G Protein
NIBR189是 EBI2(GPR183)小分子拮抗剂(IC50:11 nM)。
T10596 BR102375

Others Others
BR102375 is a non-TZD PPAR γ full agonist (EC50: 0.28 μM) for the treatment of type 2 diabetes.
T70659 BR103

BR103 is a C3aR-selective agonist that is metabolically stable.
T13138 TGFBR1-IN-1

ALK Angiogenesis; Tyrosine Kinase/Adaptors
TGFBR1-IN-1 is an inhibitor of ALK5 (IC50 of 10-100 nM).
T69603 BR103354

BR103354 is a novel fibroblast activation protein (FAP) inhibitor with anti-diabetic and anti-steatotic effects. BR103354 inhibited FAP with an IC50 value of 14 nM, showing high selectivity against dipeptidyl peptidase (DPP)-related enzymes and prolyl oligopeptidase (PREP). BR103354 exhibited good pharmacokinetic properties as evidenced by oral bioavailability of 48.4% and minimal hERG inhibition. Single co-administration of BR103354 with hFGF21 reduced nonfasting blood glucose concentrations, i...

化合物

PRL-3 Inhibitor I
Cat.No: T22136
Synonym: PRL-3 Inhibitor,BR-1
Target: Phosphatase, Others
BR10291
Cat.No: T9855
Synonym: 4-Thiazolecarboxamide, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-2-[(3,4-dichlorophenyl)methyl]-
Target: Others
NIBR189
Cat.No: T7156
Synonym:
Target: EBI2/GPR183
BR102375
Cat.No: T10596
Synonym:
Target: Others
BR103
Cat.No: T70659
Synonym:
Target:
TGFBR1-IN-1
Cat.No: T13138
Synonym:
Target: ALK
BR103354
Cat.No: T69603
Synonym:
Target:
TargetMol Loading
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