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Cat. No.	Product Name	Target	Signaling Pathways
T22272	Lifirafenib BGB-283,Beigene-283	EGFR; Raf	Angiogenesis; JAK/STAT signaling; MAPK; Tyrosine Kinase/Adaptors
	Lifirafenib (Beigene-283) 是新型高效的Raf 激酶和EGFR 抑制剂，对重组BRafV600E 和EGFR 的IC50值分别为 23 和 29 nM。
T69984	Ticalopride	5-HT Receptor	GPCR/G Protein; Neuroscience
	Ticalopride是一种5-HT3 receptor激动剂，可用于治疗消化系统疾病、口颌疾病、耳鼻咽喉疾病，可用于研究神经性贪食症、胃食管反流和肠易激综合征。
T69985	Lifirafenib HCl
	Lifirafenib, also known as Beigene-283, is a Novel potent and selective RAF Kinase and EGFR inhibitor. BGB-283-displays Potent Antitumor Activity in B-RAF Mutated Colorectal Cancers. In vitro, BGB-283 potently inhibits B-RAFV600E-activated ERK phosphorylation and cell proliferation. It demonstrates selective cytotoxicity and preferentially inhibits proliferation of cancer cells harbouring B-RAFV600E and EGFR mutation/amplification. In B-RAFV600E CRC cell lines, BGB-283 effectively inhibits the ...