Cat. No. | Product Name | Target | Signaling Pathways |
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T61580 |
Autophagy inducer 3
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Autophagy Inducer 3 is a chemical compound that exhibits autophagy-induced activity, specifically inducing robust autophagic cell death in various cancer cells while sparing normal cells. This compound induces lethal autophagy through the formation of distinct autophagic vacuoles, LC3 puncta formation, and upregulation of signature autophagy markers such as Beclin and Atg family proteins [1]. | |||
T73331 |
GSK3-IN-3
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Mitophagy; GSK-3 | Autophagy; PI3K/Akt/mTOR signaling; Stem Cells |
GSK3-IN-3 是一种线粒体自噬 (mitophagy) 诱导剂和GSK-3 抑制剂(IC50 : 3.01 μM),可诱导帕金依赖性线粒体自噬。 GSK3-IN-3 具有非 ATP 和非底物竞争性,对 6-OHDA 有神经保护作用。 |