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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T39672	Ac-Ile-Glu-Thr-Asp-pNA
	Ac-Ile-Glu-Thr-Asp-pNA is a caspase-8 substrate that undergoes enzymatic binding and cleavage specifically at the Ile-Glu-Thr-Asp (IETD) peptide sequence. This cleavage results in the release of p-nitroalinide, which can be quantitatively measured using colorimetric detection at 405 nm. This measure serves as an indicator of caspase-8 enzyme activity.
TQ0146L	Ac-DEVD-CHO acetate Caspase-3 Inhibitor I,N-acetyl-asp-glu-val-asp-al,Ac-DEVD-CHO acetate (169332-60-9 free base),乙酰基-天冬氨酰-谷氨酰-缬氨酰-天冬氨醛	Caspase	Apoptosis; Proteases/Proteasome
	Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) 是 Caspase-3 的特异性抑制剂。
T20364	Aspartylglutamate Asp-glu	Others	Others
	Aspartylglutamate is a precursor molecule. When it upon acetylation to N-acetyl-aspartyl-glutamate (NAAG) is used as a metabotropic glutamate mGlu receptor agonist.
T34601	Sekdel sequence Ser-glu-lys-asp-glu-leu	Others	Others
	Sekdel sequence, as a signal, leads to retention of at least two proteins in the endoplasmic reticulum of animal cells.
TP2419	V-9-M Cholecystokinin nonapeptide V 9 M,Prepro CCK Fragment V-9-M,Val-pro-val-glu-ala-val-asp-pro-met,Cholecystokinin Precursor (24-32),V9M,V-9-M	Beta Amyloid	Neuroscience
	V-9-M Cholecystokinin nonapeptide (Prepro CCK Fragment V-9-M) 是胆囊收缩素(CCK)的前体化合物。胆囊收缩素(CCK)是一种刺激胆囊收缩和胰腺外分泌的脑肠肽，可从狗和猫的小肠中提取的，可以引起胆囊收缩。
T29838	Albuminamide Asp-thr-his-lys-ser-glu-ile-NH2	Others	Others
	Albuminamide is a novel peptide amide that has an identical sequence to the N-terminal (1-7) fragment of bovine serum albumin.
T32082	Histidyl-aspartyl-glutamyl-leucine His-asp-glu-leu,Hdel sequence	Others	Others
	HDEL intracellular distribution is characteristic of plant endoplasmic reticulum (ER).
T33087	Lysyl-aspartyl-glutamyl-leucine Kdel sequence,Lys-asp-glu-leu	Others	Others
	Lysyl-aspartyl-glutamyl-leucine maintains type II surface membrane proteins in the endoplasmic reticulum.
TP2340	Hemoregulatory peptide 5b hp 5B,Pglu-glu-asp-cys-lys-OH,Peedck,Glp-glu-asp-cys-lys-OH,SP1 Pentapeptide
	Hemoregulatory peptide 5b is a synthetic analog of granulocyte chalone which initially identified in extracts of rodent bone marrow and human leukocytes. Monomer inhibits both formations of GM-CFC colonies and cytotoxic drug-induced recruitment of murine
T25683	Leucomyosuppressin p-Glu-asp-val-asp-his-val-phe-leu-arg-phe-NH2	Others	Others
	Leucomyosuppressin, isolated from head extracts of the cockroach Leucophaea maderae, inhibits evoked transmitter release at the mealworm neuromuscular junction.
T6990	SNAP8 Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-Nh2,SNAP 8,SNAP-8	Others	Others
	SNAP8 (Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-Nh2) 是 SNAP-25 N 末端的模拟物，它与 SNAP-25 竞争 SNARE 复合物中的位置，从而调节其形成。
TP2462	Magaratensin Asp-lys-arg-pro-tyr-ile-leu-his-glu
	Magaratensin is a neurotensin-related peptide related to the skin of Rana margarate.
T36331	Z-AEVD-FMK Z-AEVD-FMK,Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone	Others	Others
	Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases.[1] At 10 &#181M, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its active form, caspase cascade activation, and apoptosis.[2]
TP1099	M-2420 Methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl
	M-2420 is a fluorogenic substrate designed specifically for the β-secretase site found in the Swedish mutation of the amyloid precursor protein (APP).
TP2514	BPC 157 acetate Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val,GEPPPGKPADDAGLV	Others	Others
	Body Protection Compound 157 (BPC 157) is a pentadecapeptide derived from BPC, identified in gastric juice, exhibiting diverse biological activities. At 2 µg/ml, BPC 157 enhances primary rat tendon fibroblast cell migration and F-actin formation. Furthermore, doses of 0.01 and 10 µg/kg, intraperitoneally (i.p.), mitigate paw swelling, bone erosion, and mononuclear cell infiltration in the joints of rats with rheumatoid arthritis induced by complete Freund's adjuvant (CFA). It also diminishes gas...
T8761	[Leu15]-Gastrin I human Amino Acid Sequence Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Leu-Asp-Phe-NH2	Others	Others
	[Leu15]-Gastrin I human (Amino Acid Sequence Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Leu-Asp-Phe-NH2) 基因编码人体内的蛋白质 [Leu15]-胃泌素 I。在人类染色体中，GAST 基因定位于 17q21.2。胃窦中的 G 细胞产生 [Leu15]-胃泌素 I 的前体前胃泌素。前胃泌素经过裂解和加工产生胃泌素，它对整个胃肠道上皮细胞具有营养作用。胃泌素对消化系统的生长至关重要，并刺激壁细胞产生胃酸。胃泌素通过称为胆囊收缩素(CCK) 或 CCK-B 受体 (CCK-BR) 的 G 蛋白偶联受体发挥其功能。胃泌素的释放受到食物的刺激，尤其是蛋白质饮食，并受到非常低的 pH 值的抑制。萎缩性胃炎、幽门螺杆菌感染和长期服用质子泵抑制剂感染可能导致胃泌素过度表达。胃腺癌显示高水平的胃泌素。
T31808	Flrlamide, manduca Glu-asp-val-val-his-ser-phe-leu-arg-phe-Nh2,Pedvvhsflrf-NH2,Masflrfamide I	Others	Others
	Flrlamide, manduca is a bioactive peptide extracted from the central nervous system of Manduca sexta.
T76600	Ac-Trp-Glu-His-Asp-Aldehyde
	Ac-Trp-Glu-His-Asp-Aldehyde 是一种有效的选择性 caspase-1抑制剂，Ki 值为 56 pM。
T76606	Ac-Trp-Glu-His-Asp-AMC
	Ac-Trp-Glu-His-Asp-AMC (AC-WEHD-AMC) 是caspase-1的有效荧光底物。
T82388	Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone	Caspase	Apoptosis; Proteases/Proteasome
	Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone 是一种细胞渗透性且无毒的抑制剂，它能与活化的caspase-3在凋亡细胞内不可逆结合。该抑制剂的荧光强度可通过流式细胞仪、微孔板读数器或荧光显微镜检测。
TP1092	Myelin Basic Protein (MBP) (68-82), guinea pig MBP (68-82), guinea pig,豚鼠髓磷脂碱性蛋白片段68-82	Others	Others
	Myelin Basic Protein (MBP) (68-82), guinea pig 是一种髓鞘碱性蛋白 (MBP) 的片段。
TP2270	MHC class II antigen (45-57) [Homo sapiens]	Others	Others
	MHC class II antigen (45-57) [Homo sapiens] is a peptide with the sequence H2N-Asp-Leu-Asp-Lys-Lys-Glu-Thr-Val-Trp-His-Leu-Glu- Glu-OH, MW= 1868.07. MHC (major histocompatibility complex) class II molecules are found only on antigen-presenting cells and l
T80076	Ac-ESMD-CHO	Casein Kinase	Metabolism; Stem Cells
	Ac-ESMD-CHO是一种抑制caspase-3和caspase-7的化合物。该化合物能有效阻止caspase-3前体肽(CPP32)在Glu-Ser-Met-Asp(ESMD)位点发生的蛋白水解切割作用。
TP2256	heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens]	Others	Others
	Heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens] is a peptide with the sequence H2N-Phe-Thr-Val-Asp-Arg- Pro-Phe-Leu-Phe-Leu-Ile-Tyr-Glu-His-Arg-OH, MW=1953.25.
TP1484	α2β1 Integrin Ligand Peptide
	The Asp-Gly-Glu-Ala (DGEA) amino acid domain of type I collagen interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors.
T23555	Z-VEID-FMK	Others	Others
	When compared to other caspase inhibitors, Z-DRHD-FMK inhibited caspase 6 activity more effectively than the general caspase inhibitor of Z-Val-Ala-Asp (OMe)-fluoromethy ketone (Z-VAD-FMK) or the caspase 6 inhibitor Z-Val-Glu(Ome)-Ile-Asp(OMe)-fluorometh
T82604	Dby HY Peptide (608-622), mouse
	Dby HY Peptide (608-622), mouse 是一种具有生物活性的HYAb表位肽，属于高度保守的RNA解旋酶基因家族。该肽含有核心DEAD (Asp-Glu-Ala-Asp) 盒肽基序，故命名为Dby（死盒RNA解旋酶Y）。其序列中苯丙氨酸作为锚点，FNSNRANSS构成“核心”序列，对于HYAb表位至关重要。
TP2287	Rac GTPase fragment	Others	Others
	Rac GTPase fragment is a peptide with the sequence H2N-Val-Phe-Asp-Glu-Ala-Ile-Arg-Ala-Val-OH, MW= 1019.15. Rac is a subfamily of the Rho family of GTPases, small signaling G proteins (more specifically a GTPase).

化合物

Ac-Ile-Glu-Thr-Asp-pNA

Cat.No: T39672

Ac-DEVD-CHO acetate

Cat.No: TQ0146L

Synonym: Caspase-3 Inhibitor I,N-acetyl-asp-glu-val-asp-al,Ac-DEVD-CHO acetate (169332-60-9 free base),乙酰基-天冬氨酰-谷氨酰-缬氨酰-天冬氨醛

Target: Caspase

Aspartylglutamate

Cat.No: T20364

Synonym: Asp-glu

Target: Others

Sekdel sequence

Cat.No: T34601

Synonym: Ser-glu-lys-asp-glu-leu

Target: Others

V-9-M Cholecystokinin nonapeptide

Cat.No: TP2419

Synonym: V 9 M,Prepro CCK Fragment V-9-M,Val-pro-val-glu-ala-val-asp-pro-met,Cholecystokinin Precursor (24-32),V9M,V-9-M

Target: Beta Amyloid

Cat.No: T29838

Synonym: Asp-thr-his-lys-ser-glu-ile-NH2

Target: Others

Histidyl-aspartyl-glutamyl-leucine

Cat.No: T32082

Synonym: His-asp-glu-leu,Hdel sequence

Target: Others

Lysyl-aspartyl-glutamyl-leucine

Cat.No: T33087

Synonym: Kdel sequence,Lys-asp-glu-leu

Target: Others

Hemoregulatory peptide 5b

Cat.No: TP2340

Synonym: hp 5B,Pglu-glu-asp-cys-lys-OH,Peedck,Glp-glu-asp-cys-lys-OH,SP1 Pentapeptide

Leucomyosuppressin

Cat.No: T25683

Synonym: p-Glu-asp-val-asp-his-val-phe-leu-arg-phe-NH2

Target: Others

Cat.No: T6990

Synonym: Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-Nh2,SNAP 8,SNAP-8

Target: Others

Cat.No: TP2462

Synonym: Asp-lys-arg-pro-tyr-ile-leu-his-glu

Cat.No: T36331

Synonym: Z-AEVD-FMK,Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone

Target: Others

Cat.No: TP1099

Synonym: Methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl

BPC 157 acetate

Cat.No: TP2514

Synonym: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val,GEPPPGKPADDAGLV

Target: Others

[Leu15]-Gastrin I human

Cat.No: T8761

Synonym: Amino Acid Sequence Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Leu-Asp-Phe-NH2

Target: Others

Flrlamide, manduca

Cat.No: T31808

Synonym: Glu-asp-val-val-his-ser-phe-leu-arg-phe-Nh2,Pedvvhsflrf-NH2,Masflrfamide I

Target: Others

Ac-Trp-Glu-His-Asp-Aldehyde

Cat.No: T76600

Ac-Trp-Glu-His-Asp-AMC

Cat.No: T76606

Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone

Cat.No: T82388

Target: Caspase

Myelin Basic Protein (MBP) (68-82), guinea pig

Cat.No: TP1092

Synonym: MBP (68-82), guinea pig,豚鼠髓磷脂碱性蛋白片段68-82

Target: Others

MHC class II antigen (45-57) [Homo sapiens]

Cat.No: TP2270

Target: Others

Cat.No: T80076

Target: Casein Kinase

heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens]

Cat.No: TP2256

Target: Others

α2β1 Integrin Ligand Peptide

Cat.No: TP1484

Cat.No: T23555

Target: Others

Dby HY Peptide (608-622), mouse

Cat.No: T82604

Rac GTPase fragment

Cat.No: TP2287

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T2596	N-Acetyl-β-Asp-Glu	Others	Others
	N-Acetyl-β-Asp-Glu 是一种肽类神经递质，是哺乳动物神经系统中第三常见的神经递质。 NAAG 由通过肽键偶联的 N-乙酰天冬氨酸 (NAA) 和谷氨酸组成。

天然产物

N-Acetyl-β-Asp-Glu

Cat.No: T2596

Target: Others

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