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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
TP1447L1	Arg-Gly-Asp-Cys acetate Arg-Gly-Asp-Cys acetate(109292-46-8 free base),RGDC acetate	Others	Others
	Arg-Gly-Asp-Cys acetate 抑制血小板聚集和纤维蛋白原结合。 Arg-Gly-Asp-Cys acetate 是纤连蛋白与细胞粘附分子的结合基序。
T10366L	Arg-Gly-Asp-Ser acetate Arg-Gly-Asp-Ser acetate(91037-65-9 free base)	Integrin	Cytoskeletal Signaling
	Arg-Gly-Asp-Ser acetate 是一种整合素结合序列，可直接特异性结合 pro-caspase-8、pro-caspase-9 和 pro-caspase-3，但不结合 pro-caspase-1。它抑制整合素受体功能。
TP1459L	Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base)	Integrin	Cytoskeletal Signaling
	Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base) 是一种源自纤连蛋白的细胞结合区域的细胞结合蛋白结构域。
T4613	Arg-Gly-Asp TFA (99896-85-2(free base)) RGD Trifluoroacetate,RGD	Integrin	Cytoskeletal Signaling
	Arg-Gly-Asp TFA (99896-85-2(free base)) (RGD Trifluoroacetate) 是一种三肽，可有效触发细胞粘附、定位某些细胞系并引发特定的细胞反应；与整合素结合。
T6966	RGD RGD (Arg-Gly-Asp) Peptides,Arg-Gly-Asp,RGD Peptides	Integrin	Cytoskeletal Signaling
	RGD (RGD (Arg-Gly-Asp) Peptides) 是一种细胞粘附基序，可以模拟细胞粘附蛋白并与整合素结合。
TP1459	Gly-Arg-Gly-Asp-Ser
	Gly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.
TP1447	Arg-Gly-Asp-Cys RGDC
	Arg-Gly-Asp-Cys is the binding motif of fibronectin and cell adhesion molecules, which can inhibit platelet aggregation and fibrinogen binding.
T39655	Arg-Gly-Asp-Cys TFA
	Arg-Gly-Asp-Cys TFA serves as the binding motif through which fibronectin interacts with cell adhesion molecules. This compound has the ability to hinder platelet aggregation and fibrinogen binding.
TP1582	Gly-Arg-Gly-Asp-Ser (TFA)(96426-21-0,free) Gly-Arg-Gly-Asp-Ser (TFA)
	Gly-Arg-Gly-Asp-Ser (GRGDS) is a cell binding protein domain derived from the cell-binding region of fibronectin. Osteopontin uses this motif for cell adhesion.
T10366	Arg-Gly-Asp-Ser Fibronectin tetrapeptide,RGDS peptide	Others	Others
	Arg-Gly-Asp-Ser is an integrin-binding sequence that inhibits integrin receptor function. It decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, MMP-9, and iNOS
T10920	Cyclo(Arg-Gly-Asp-D-Phe-Val) TFA	Others	Others
	Arg-Gly-Asp-D-Phe-Val (TFA) has anti-tumor activity and is an inhibitor of integrin αvβ3.
TP1043	Arg-Gly-Asp-Ser (TFA)(91037-65-9,free) Fibronectin tetrapeptide (TFA),RGDS peptide (TFA),Arg-Gly-Asp-Ser (TFA)
	Arg-Gly-Asp-Ser (TFA) is an integrin binding sequence that inhibits integrin receptor function.
T35582	H-Arg-Gly-Asp-Cys-OH (trifluoroacetate salt)
	H-Arg-Gly-Asp-Cys-OH is a tetrapeptide that contains the arginine-glycine-aspartate (RGD) motif, a sequence that acts as a recognition site for various adhesion proteins.1It inhibits the binding of fibrinogen to endothelial cells and ADP-stimulated platelets with IC50values of 320 and 35 μM, respectively.2Implantation of titanium rods coated with H-Arg-Gly-Asp-Cys-OH increases bone formation in rat femurs.3H-Arg-Gly-Asp-Cys-OH has been conjugated to polyethylenimine to improve gene transfection ...
T31919	Gdpflrfamide Gly-asp-pro-phe-leu-arg-phe-amide
	Gdpflrfamide is a neuropeptide that existed in the snail Lymnaea stagnalis.
TP2347	Peptide 78 Peptide78,Thr-met-arg-lys-pro-arg-ser-gly-asn-pro-asp-val-ala-asn,Peptide-78
	Peptide 78 is identical to peptide 74 except that serine replaces cysteine. It does not inhibit 72-kDa type IV collagenase.
T83690	[Leu144, Arg147]-PLP (139-151) TFA [Leu144, Arg147] Proteolipid Peptide (139-151),H-His-Ser-Leu-Gly-Lys-Leu-Leu-Gly-Arg-Pro-Asp-Lys-Phe-OH
	[Leu144,Arg147]-PLP (139-151)是髓鞘脂蛋白(PLP)的一种突变肽段，包含位于144和147位置的色氨酸到亮氨酸以及组氨酸到精氨酸的替换。使用[Leu144, Arg147]-PLP (139-151)（50 µg）乳化于完全弗氏佐剂(CFA)免疫后，能增加小鼠脾脏中的IL-4水平。它在体外抑制Th1细胞激活，但在体内不抑制，其中它诱导调节性T细胞的产生。用[Leu144, Arg147]-PLP (139-151)预免疫可以延迟由脑炎肽PLP (178-191)、髓磷脂少突细胞蛋白(MOG) (92-106)或髓鞘基础蛋白(MBP)在小鼠中诱导的实验性自身免疫性脑炎(EAE)的发病。
T64691	Gly-Arg-Gly-Asp-Ser trifluoroacetate
	Gly-Arg-Gly-Asp-Ser trifluoroacetate 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64691。
T75761	Gly-Arg-Gly-Asp-Ser TFA GRGDS TFA
	Gly-Arg-Gly-Asp-Ser (TFA) 是一种与糖蛋白和骨桥蛋白在细胞结合域中起作用的五肽。该化合物能够与整合素整联蛋白受体αvβ3和αvβ5结合，其IC50值分别约为5 μM和6.5 μM。
T73870	Arg-Gly-Asp-Ser TFA
	Arg-Gly-Asp-Ser (TFA) 为整联蛋白结合序列，专门抑制整联蛋白受体(integrin receptor)功能。它能够直接且特异性地与pro-caspase-8、pro-caspase-9和pro-caspase-3结合，而不与pro-caspase-1发生作用。
T80142	Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) c(GRGDSP)	Integrin	Cytoskeletal Signaling
	Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)（c(GRGDSP)）为RGD 抑制肽。该化合物作为合成的α5β1整联蛋白配体，能够竞争性阻断 invasin（Inv）与Caco-2细胞表面α5β1整联蛋白的相互结合。
T80075	Cyclo(Ala-Arg-Gly-Asp-Mamb) XJ735	Integrin	Cytoskeletal Signaling
	Cyclo(Ala-Arg-Gly-Asp-Mamb) 是选择性的RGD肽拮抗剂，用于肺动脉高压治疗研究。
T80127	FITC-Ahx-Gly-Arg-Gly-Asp-Ser-Pro	Integrin	Cytoskeletal Signaling
	FITC-Ahx-Gly-Arg-Gly-Asp-Ser-Pro为FITC标记的GRGDSP，后者为整联蛋白(integrin)抑制剂，能阻止肿瘤细胞与血管内皮细胞粘附，进而抑制肿瘤转移。
T82633	Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg-NH2
	Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg-NH2是源自层粘连蛋白B1链的线性肽，能够干预肿瘤细胞对基底膜的附着与侵袭，且表现出抗血管生成活性。
T75990	Cyclo(Arg-Gly-Asp-D-Phe-Val)
	Cyclo(Arg-Gly-Asp-D-Phe-Val) 为一种整合素αvβ3抑制剂，具有抗肿瘤活性，并可用于急性髓系白血病的研究。
T76068	Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA
	Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA 是一种环状RGD多肽，对αvβ3有高亲和性，能干扰细胞整合素之间的相互作用。此化合物能抑制胚胎干细胞(ESC)的多潜能性基因表达，并可在体内减少mESC的致瘤潜力，因此适用于肿瘤研究领域。
T76582	Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys (Disulfide bridge:cys1-cys10)
	Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys (Disulfide bridge:cys1-cys10)，为含环状RGD活性序列的十肽，作为整合素(Integrin)αIIbβ3的拮抗剂，能够抑制血小板与proMMP-13的粘附。
T21662L	Cadherin Peptide, avian Acetate Cadherin Peptide, avian Acetate (127650-08-2 Free base)	Others	Others
	Cadherin Peptide, avian Acetate 是一种肽，序列为 Leu-Arg-Ala-His-Ala-Val-Asp-Val-Asn-Gly-NH2。钙粘蛋白是一类 1 型跨膜蛋白。
TP1526L1	Fibronectin CS1 Peptide acetate	Others	Others
	Fibronectin CS1 Peptide acetate 存在于 III 型同源连接段 (IIICS) 以及 C-274（细胞结合结构域）中。 Fibronectin CS1 Peptide 缺乏含有 Arg-Gly-Asp 的结构域，在自发和实验性转移模型中积极抑制肿瘤转移。
TP1092	Myelin Basic Protein (MBP) (68-82), guinea pig MBP (68-82), guinea pig,豚鼠髓磷脂碱性蛋白片段68-82	Others	Others
	Myelin Basic Protein (MBP) (68-82), guinea pig 是一种髓鞘碱性蛋白 (MBP) 的片段。
TP1474	LXW7	Integrin	Cytoskeletal Signaling
	LXW7 是一种整合素αvβ3抑制剂，是含 Arg-Gly-Asp (RGD) 的环状肽，对αvβ3整联蛋白具有很高的结合亲和力，IC50为 0.68 μM。它可增强 VEGFR-2 磷酸化和 ERK1/2 活化，具有抗炎活性。
TP1421	GRGDSP
	Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.
T81186	SDGR
	SDGR是一种四肽，含有Ser-Asp-Gly-Arg序列，能够有效抑制纤连蛋白介导的细胞附着。
T75724	LXW7 TFA
	LXW7 TFA, 包含 Arg-Gly-Asp (RGD) 的环状肽，作为整合素αvβ3抑制剂，展示出对αvβ3整联蛋白高度的结合亲和力，其IC50值为0.68 μM。此外，LXW7 TFA 能够促进 VEGFR-2 磷酸化和 ERK1/2 激活，显示出抗炎活性。
TP2148	LXW7 TFA (1313004-77-1 free base) LXW7 TFA	Integrin	Cytoskeletal Signaling
	LXW7 TFA, a cyclic peptide containing Arg-Gly-Asp (RGD), is an integrin αvβ3 inhibitor with an anti-inflammatory effect. LXW7 has a high binding affinity to αvβ3 integrin (IC50: 0.68 μM). It increases the phosphorylation of VEGFR-2 and activation of ERK1/2.
T70083	Cilengitide hydrochloride
	Cilengitide hydrochloride sis the salt form of Cilengitide, a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.
TP1526	Fibronectin CS1 Peptide
	he connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. CS1 peptide of fibronectin, which lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontan
T76378	RGD-4C
	RGD-4C（ACDCRGDCFC）是一种携带Arg-Gly-Asp（RGD）序列的肽，具备与αv整合素结合的能力，用于模拟细胞外基质蛋白的整合素识别特性。作为αv整合素的配体，它能够与生物活性分子进行偶联，进而在动物模型中展现出抗肿瘤活性。
T75765	GRGDSPK TFA
	GRGDSPK TFA (EMD 56574 TFA) 是一种含有精氨酸-甘氨酸-天冬氨酸 (RGD) 序列的多肽。作为竞争性且可逆的抑制剂，它能够抑制整联蛋白与纤连蛋白的结合，用于探究整联蛋白在骨形成及吸收过程中的功能。
TP2260	Immunoglobulin M heavy chain (IGHM) fragment [Homo sapiens]	Others	Others
	Immunoglobulin M heavy chain (IGHM) fragment [Homo sapiens] is a fragment (Gly-Val-Ala-Leu-His-Arg-Pro-Asp-Val-Tyr-Leu-Leu-Pro-Pro-Ala-Arg) on the human immunoglobulin micro heavy chain. Immunoglobulins (Ig) are the antigen recognition molecules of B cell

化合物

Arg-Gly-Asp-Cys acetate

Cat.No: TP1447L1

Synonym: Arg-Gly-Asp-Cys acetate(109292-46-8 free base),RGDC acetate

Target: Others

Arg-Gly-Asp-Ser acetate

Cat.No: T10366L

Synonym: Arg-Gly-Asp-Ser acetate(91037-65-9 free base)

Target: Integrin

Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base)

Cat.No: TP1459L

Target: Integrin

Arg-Gly-Asp TFA (99896-85-2(free base))

Cat.No: T4613

Synonym: RGD Trifluoroacetate,RGD

Target: Integrin

Cat.No: T6966

Synonym: RGD (Arg-Gly-Asp) Peptides,Arg-Gly-Asp,RGD Peptides

Target: Integrin

Gly-Arg-Gly-Asp-Ser

Cat.No: TP1459

Arg-Gly-Asp-Cys

Cat.No: TP1447

Synonym: RGDC

Arg-Gly-Asp-Cys TFA

Cat.No: T39655

Gly-Arg-Gly-Asp-Ser (TFA)(96426-21-0,free)

Cat.No: TP1582

Synonym: Gly-Arg-Gly-Asp-Ser (TFA)

Arg-Gly-Asp-Ser

Cat.No: T10366

Synonym: Fibronectin tetrapeptide,RGDS peptide

Target: Others

Cyclo(Arg-Gly-Asp-D-Phe-Val) TFA

Cat.No: T10920

Target: Others

Arg-Gly-Asp-Ser (TFA)(91037-65-9,free)

Cat.No: TP1043

Synonym: Fibronectin tetrapeptide (TFA),RGDS peptide (TFA),Arg-Gly-Asp-Ser (TFA)

H-Arg-Gly-Asp-Cys-OH (trifluoroacetate salt)

Cat.No: T35582

Cat.No: T31919

Synonym: Gly-asp-pro-phe-leu-arg-phe-amide

Cat.No: TP2347

Synonym: Peptide78,Thr-met-arg-lys-pro-arg-ser-gly-asn-pro-asp-val-ala-asn,Peptide-78

[Leu144, Arg147]-PLP (139-151) TFA

Cat.No: T83690

Synonym: [Leu144, Arg147] Proteolipid Peptide (139-151),H-His-Ser-Leu-Gly-Lys-Leu-Leu-Gly-Arg-Pro-Asp-Lys-Phe-OH

Gly-Arg-Gly-Asp-Ser trifluoroacetate

Cat.No: T64691

Gly-Arg-Gly-Asp-Ser TFA

Cat.No: T75761

Synonym: GRGDS TFA

Arg-Gly-Asp-Ser TFA

Cat.No: T73870

Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)

Cat.No: T80142

Synonym: c(GRGDSP)

Target: Integrin

Cyclo(Ala-Arg-Gly-Asp-Mamb)

Cat.No: T80075

Synonym: XJ735

Target: Integrin

FITC-Ahx-Gly-Arg-Gly-Asp-Ser-Pro

Cat.No: T80127

Target: Integrin

Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg-NH2

Cat.No: T82633

Cyclo(Arg-Gly-Asp-D-Phe-Val)

Cat.No: T75990

Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA

Cat.No: T76068

Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys (Disulfide bridge:cys1-cys10)

Cat.No: T76582

Cadherin Peptide, avian Acetate

Cat.No: T21662L

Synonym: Cadherin Peptide, avian Acetate (127650-08-2 Free base)

Target: Others

Fibronectin CS1 Peptide acetate

Cat.No: TP1526L1

Target: Others

Myelin Basic Protein (MBP) (68-82), guinea pig

Cat.No: TP1092

Synonym: MBP (68-82), guinea pig,豚鼠髓磷脂碱性蛋白片段68-82

Target: Others

Cat.No: TP1474

Target: Integrin

Cat.No: TP1421

Cat.No: T81186

Cat.No: T75724

LXW7 TFA (1313004-77-1 free base)

Cat.No: TP2148

Synonym: LXW7 TFA

Target: Integrin

Cilengitide hydrochloride

Cat.No: T70083

Fibronectin CS1 Peptide

Cat.No: TP1526

Cat.No: T76378

Cat.No: T75765

Immunoglobulin M heavy chain (IGHM) fragment [Homo sapiens]

Cat.No: TP2260

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN5221	(-)-Variabilin
	Variabilin, a novel inhibitor of human platelet aggregation, it is a potent RGD (Arg-Gly-Asp)-containing antagonist of the fibrinogen receptor glycoprotein IIb-IIIa (GPIIb-IIIa; αIIbβ3) and the vitronectin receptor αvβ3.Variabilin is also an antimicrobial furanosesterterpene. Variabilin is an inhibitor of human secretory and cytosolic phospholipase A2 (PLA2) activities that controls eicosanoid production in vitro and in vivo, inhibits neutrophil degranulation and superoxide generation in vitro a...

天然产物

Cat.No: TN5221

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