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Cat. No. Product Name Target Signaling Pathways
T4451 Estramustine phosphate sodium

Ro 21-8837/001,Estramustine phosphate disodium,雌莫司汀磷酸钠

Apoptosis; Microtubule Associated Apoptosis; Cytoskeletal Signaling
Estramustine phosphate sodium (Ro 21-8837/001) 是雌二醇类似物,是一种具有口服活性抗微管化疗剂,通过与微管相关蛋白和微管蛋白结合而使微管解聚。它可诱导前列腺癌细胞凋亡,可研究前列腺癌。
T13073 Taltobulin trifluoroacetate

HTI-286 trifluoroacetate,SPA-110 trifluoroacetate

Others Others
Taltobulin trifluoroacetate is a synthetic analogue of the tripeptide hemiasterlin, is a potent agent of antimicrotubule that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.
T17727 CCK2R Ligand-Linker Conjugates 1

Others Others
CCK2R Ligand-Linker Conjugate 1 is a hydrophilic peptide linker that conjugates to the cytotoxic antimicrotubule agents Desacetyl Vinblastine Hydrazide (DAVBH) and Tubulysin B Hydrazide (TubBH) as ligand-linker conjugates[1].
T13073L Taltobulin hydrochloride (228266-40-8 free base)

SPA-110 hydrochloride,Taltobulin hydrochloride,HTI-286 hydrochloride

Others Others
Taltobulin hydrochloride is a synthetic analogue of the tripeptide hemiasterlin, is a potent agent of antimicrotubule that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.
T75240 Taltobulin hydrochloride

Taltobulin hydrochloride (HTI-286 hydrochloride) 是一种合成的三肽半胱氨酸类似物,为高效抗微管剂,能够在体内外绕过P-糖蛋白介导的药物耐药性。该化合物通过抑制微管蛋白的聚合和破坏细胞内微管结构,进而引起细胞有丝分裂停滞和细胞凋亡。
T60737 LG308

LG308 是一种新型合成化合物,具有抗微管活性。LG308 诱导细胞凋亡和细胞死亡,并且显著抑制肿瘤生长,具有前列腺癌的研究潜力。LG308 诱导有丝分裂阻滞并显着抑制 G2/M 的进程,这与细胞周期蛋白 B1 和有丝分裂标志物 MPM-2 的上调以及 cdc2 的去磷酸化有关。

化合物

Estramustine phosphate sodium
Cat.No: T4451
Synonym: Ro 21-8837/001,Estramustine phosphate disodium,雌莫司汀磷酸钠
Target: Apoptosis, Microtubule Associated
Taltobulin trifluoroacetate
Cat.No: T13073
Synonym: HTI-286 trifluoroacetate,SPA-110 trifluoroacetate
Target: Others
CCK2R Ligand-Linker Conjugates 1
Cat.No: T17727
Synonym:
Target: Others
Taltobulin hydrochloride (228266-40-8 free base)
Cat.No: T13073L
Synonym: SPA-110 hydrochloride,Taltobulin hydrochloride,HTI-286 hydrochloride
Target: Others
Taltobulin hydrochloride
Cat.No: T75240
Synonym:
Target:
LG308
Cat.No: T60737
Synonym:
Target:
TargetMol Loading
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