Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7743 |
ANGIOTENSIN IV TFA(12676-15-2(free base))
|
RAAS | Endocrinology/Hormones |
ANGIOTENSIN IV TFA(12676-15-2(free base)) 是一种不太有效的血管紧张素 AT1 受体激动剂。 | |||
T5824 |
Angiotensin II (3-8), human
Angiotensin IV |
RAAS | Endocrinology/Hormones |
Angiotensin II (3-8), human 是活性稍弱的血管紧张素AT1受体激动剂。 | |||
T7376 |
Dihexa
PNB-0408,Hexanoyl-Tyr-Ile-Ahx-NH2,N-hexanoic-Try-Ile-(6)-amino hexanoic amide |
c-Met/HGFR | Tyrosine Kinase/Adaptors |
Dihexa (Hexanoyl-Tyr-Ile-Ahx-NH2) 是肝细胞生长因子/c-Met (HGF/c-Met) 系统的激活剂,它与 HGF (Kd = 65 pM) 结合,是肽血管紧张素 IV 的类似物。 | |||
T70932 | L6H9 | ||
L6H9 is a novel inhibitor of myeloid differentiation factor 2 (MD2), suppressing HG-induced expression of ACE and AT1 receptor and Angiotensin II (AngII) production in renal NRK‐52E cells, resulting in the decrease in fibrosis markers such as TGF-β and collagen IV. | |||
TP1404 |
Hemorphin-7
|
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Hemorphin-7 binds to the angiotensin IV receptor, triggering multiple effects including cellular proliferation and memory enhancement. Hemorphins are endogenous peptides belonging to the family of atypical opioid peptides released from hydrolyzed hemoglob | |||
TP1990 |
Norleual
|
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Angiotensin IV analog. Highly potent HGF/c-MET inhibitor (IC50 = 3 pM). Inhibits HGF-induced MDCK cell proliferation and invasion in vitro. Also AT4 receptor antagonist; disrupts LTP stabilization. Antiangiogenic. | |||
T75940 |
Norleual TFA
|
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Norleual TFA 是一种血管紧张素 (Ang) IV 类似物,是一种肝细胞生长因子(HGF)/c-Met 抑制剂,IC50为 3 pM。Norleual TFA 还是一种AT4拮抗剂,具有强大的抗血管生成活性。 |