Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1859 |
AZD-8055
|
Apoptosis; mTOR; Autophagy | Apoptosis; Autophagy; PI3K/Akt/mTOR signaling |
AZD-8055 是一种选择性、具有口服活性和 ATP 竞争性的 mTOR 抑制剂,IC50为 0.8 nM。AZD-8055 抑制 mTORC1和 mTORC2。 | |||
T71255 |
AZD-8055 fumarate
|
||
AZD-8055 fumarate is a potent, selective, and orally bioavailable ATP-competitive mammalian target of rapamycin kinase inhibitor with in vitro and in vivo antitumor activity. | |||
T71254 |
Clopidogrel HCl
|
||
Clopidogrel HCl is the salt form of Clopidogrel (free base), an inhibitor of ADP-induced platelet aggregation acting by direct inhibition of adenosine diphosphate (ADP) binding to its receptor and of the subsequent ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. |