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Search Results for " atp-pfk "

Targets Recommended: Apoptosis Glucokinase Autophagy

1

抑制剂 & 化合物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T3105	PFK-158	Apoptosis; Glucokinase; Autophagy	Apoptosis; Autophagy; Metabolism
	PFK158 是一种选择性的PFKFB3抑制剂，IC50值为 137 nM。它可减少癌细胞中葡萄糖的摄取，ATP 的产生，乳酸的释放，并诱导细胞凋亡和自噬。它还可以增强 Colistin 对细菌的抵抗力，具有广泛的抗肿瘤活性。

化合物

Cat.No: T3105

Target: Apoptosis, Glucokinase, Autophagy

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-05160	PFKP Protein, Human, Recombinant (His & GST) PFK-P,PFKF,ATP-PFK,phosp...	Human	Baculovirus Insect Cells
	PFKP plays a critical role in cell proliferation in breast cancer cells. PFKP is necessary for starvation-mediated autophagy, glycolysis, and EMT, thereby promoting the malignant progression of OSCC. The Snail-PFKP axis plays an important role in cancer cell survival via regulation of glucose flux between glycolysis and PPP.
TMPY-04479	PFKM Protein, Human, Recombinant (His & GST) ATP-PFK,PFK-1,PFK1,P...	Human	Baculovirus Insect Cells
	PFK1, also known as PFKM, is a regulatory glycolytic enzyme. PFK1 converts fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP. It is a muscle-type isozyme. There are three phosphofructokinase isozymes in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Mutations i...
TMPJ-00384	PFKM Protein, Human, Recombinant (His) Phosphofructo-1-kinase isozyme A,Phosphohexokinase,PFK	Human	HEK293 Cells
	6-phosphofructokinase, muscle type is a muscle-type isozyme that in humans is encoded by the PFKM gene. It belongs to the phosphofructokinase family and Two domains subfamily. PFKM functions as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. PFK1 converts fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP.

重组蛋白

PFKP Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-05160

Species: Human

Expression System: Baculovirus Insect Cells

PFKM Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04479

Species: Human

Expression System: Baculovirus Insect Cells

PFKM Protein, Human, Recombinant (His)

Cat.No: TMPJ-00384

Species: Human

Expression System: HEK293 Cells

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