4
2
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T72553 |
ARTD10/PARP10-IN-1
|
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
ARTD10/PARP10-IN-1 是一种强效性的 PARP 抑制剂,抑制单 ADP 核糖转移酶 ARTD7/PARP15,ARTD8/PARP14,ARTD10/PARP10 和聚 ADP-核糖聚合酶-1 (ARTD1/PARP1),具有潜在的抗癌抗肿瘤活性,可用于研究前列腺癌和乳腺癌。 | |||
T72554 |
ARTD10/PARP10-IN-2
|
||
ARTD10/PARP10-IN-2 是一种强效、非选择性的PARP 抑制剂。ARTD10/PARP10-IN-2 靶向单 ADP 核糖转移酶 (ARTD10/PARP10) 和聚 ADP-核糖聚合酶-1 (ARTD1/PARP1),IC50分别为 2.0 μM,和 9.7 μM。 | |||
T3168 |
MN-64
MN64 |
Others; PARP; Wnt/beta-catenin | Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Others; Stem Cells |
MN-64 是一种有效的tankyrase 1抑制剂,对TNKS1、TNKS2、ARTD1 和 ARTD2 的IC50值分别为 6、72、19.1 和 39.4 μM。 | |||
T11143 |
EB-47
|
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
EB-47 是一种有效的 PARP-1/ARTD-1 选择性抑制剂,IC50 值为 45 nM,对 ARTD5 的IC50 值为 410 nM,表现出温和的药效。EB-47 模拟底物 NAD+,从烟酰胺延伸至腺苷亚区结合。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01188 |
PARP Protein, Human, Recombinant (His)
ADPRT1,ADPRT,pADPRT-1,PPOL,ARTD |
Human | Baculovirus Insect Cells |
PARP Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 114.5 kDa and the accession number is A0A024R3T8. | |||
TMPY-02465 |
PARP Protein, Mouse, Recombinant (His)
AI893648,Adprp,5830444G22Rik,C80510,sPARP-1 |
Mouse | Baculovirus Insect Cells |
PARP Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 115 kDa and the accession number is Q921K2. |