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Search Results for " arm1 "

Targets Recommended: Aminopeptidase Epoxide Hydrolase

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T21859	ARM1	Aminopeptidase; Epoxide Hydrolase	Metabolism
	ARM1 是氨基肽酶和环氧化物水解酶抑制剂，IC50分别为为7.61 µM 和12.4 µM。
T60908	SARM1-IN-2	Others	Others
	SARM1-IN-2 是一种有效的 SARM1 抑制剂，可用于研究代谢系统和神经系统相关疾病。
T10682L	CARM1-IN-1 CARM1-IN-7G	Histone Methyltransferase	Chromatin/Epigenetic
	CARM1-IN-1 (CARM1-IN-7G) 是 CARM1 的选择性抑制剂，IC50 为 8.6 μM。 CARM1-IN-1 对 PRMT1 和 SET7 的活性较弱，IC50 > 600 μM。
T79007	CARM1-IN-3	Histone Methyltransferase	Chromatin/Epigenetic
	CARM1-IN-3 (compound 17b) 是一种针对co-activator associated argininemethyltransferase (CARM1)的高效选择性抑制剂，其IC50值为 0.07 µM。
T63180	CARM1-IN-3 dihydrochloride
	CARM1-IN-3 dihydrochloride (compound 17b) CARM1-IN-3二盐酸盐（化合物17b）是一种强效的、选择性辅助共激活因子相关的精氨酸甲基转移酶（CARM1）抑制剂，能够作用于 CARM1 (IC50: 0.07 μM)和 CARM3 (IC50>25 μM)。
T64186	CARM1-IN-1 hydrochloride
	CARM1-IN-1 hydrochloride 是一种高效的、选择性的 CARM1 抑制剂 (IC50: 8.6 μM)，对 PRMT1 和 SET7 抑制作用很低。
T79742	CARM1 degrader-2	Histone Methyltransferase	Chromatin/Epigenetic
	CARM1 degrader-2 (compound 3e) 是一种效能高的CARM1降解剂，其DC50为8.8 nM。该化合物通过VHL途径及蛋白酶体作用实现CARM1的降解，进而抑制其底物PABP1和BAF155的甲基化作用，能够有效抑制乳腺癌细胞迁移。
T79741	CARM1 degrader-1	Histone Methyltransferase	Chromatin/Epigenetic
	CARM1 degrader-1 (compound 3b) 是一种针对co-activator associated argininemethyltransferase (CARM1) 的降解剂，其DC50为8.1 nM。它通过VHL和蛋白酶体依赖的途径降解CARM1，从而抑制了CARM1底物（例如PABP1和BAF155）的甲基化，进而抑制乳腺癌细胞的迁移。

化合物

ARM1

Cat.No: T21859

Synonym:

Target: Aminopeptidase, Epoxide Hydrolase

Synonym: CARM1-IN-7G

Target: Histone Methyltransferase

CARM1-IN-3

Cat.No: T79007

Synonym:

Target: Histone Methyltransferase

CARM1-IN-3 dihydrochloride

Cat.No: T63180

Synonym:

Target:

CARM1-IN-1 hydrochloride

Target: Histone Methyltransferase

CARM1 degrader-1

Cat.No: T79741

Synonym:

Target: Histone Methyltransferase

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01900	Kallikrein 4/KLK4 Protein, Human, Recombinant (His) PSTS,kallikrein,kallikrein-related peptidase 4,EMSP,EMSP...	Human	HEK293 Cells
	Kallikrein-4, also known as Enamel matrix serine proteinase 1, Kallikrein-like protein 1, KLK-L1, Serine protease 17, KLK4, PRSS17, and EMSP1, is a secreted protein that belongs to the peptidase S1 family and Kallikrein subfamily. Kallikrein-4 / KLK4 is a serine protease expressed during enamel maturation, and proteolytic processing of the enamel matrix by KLK4 is critical for proper enamel formation. Kallikrein-4 / KLK4 contains one peptidase S1 domain. Kallikrein-4 / KLK4 is secreted by transi...
TMPH-01740	SARM1 Protein, Human, Recombinant (His & Myc)	Human	Baculovirus Insect Cells
	SARM1 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 80.4 kDa and the accession number is Q6SZW1.
TMPH-01741	SARM1 Protein, Human, Recombinant (His & KSI)	Human	E. coli
	SARM1 Protein, Human, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 48.8 kDa and the accession number is Q6SZW1.