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Search Results for " alr2 "

Targets Recommended: Reductase

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T77523	ALR2-IN-1	Reductase	Endocrinology/Hormones; Metabolism
	ALR2-IN-1 是一种有效的且具有选择性的 ALR2 抑制剂，IC50值为1.42 μM。ALR2-IN-1 具有抗糖和抗氧化活性，可用于研究糖尿病并发症。
T73304	ALR2-IN-2
	ALR2-IN-2, 作为一种高效的醛糖还原酶 (ALR2) 抑制剂，对大鼠ALR2的IC50值为27 nM，对ALR1的IC50值为228 nM。此化合物适用于糖尿病并发症的研究。
T73305	ALR2-IN-3
	ALR2-IN-2 是一种有效的醛糖还原酶 (ALR2) 抑制剂，抑制大鼠 ALR2和 ALR1的 IC50值分别为为 22 nM 和 116 nM。ALR2-IN-2 可用于研究糖尿病并发症。
T2013	Ponalrestat	Reductase	Endocrinology/Hormones; Metabolism
	Ponalrestat 是一种口服有效的，选择性的和非竞争性的醛糖还原酶抑制剂，对 ALR2选择性选择性较高，Ki 为 7.7 nM，对 ALR1 的选择性较弱，Ki 为 60 μM。Ponalrestat 抑制葡萄糖向山梨糖醇的转化。
T7478	2-Chloro-1-(4-fluorobenzyl)benzimidazole	Reductase	Endocrinology/Hormones; Metabolism
	2-Chloro-1-(4-fluorobenzyl)benzimidazole 是醛糖还原酶 (ALR2) 的抑制剂。
T27583	IDD388 IDD-388,IDD 388	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	IDD388 是一种具有选择性和高效性的醛糖还原酶 (ALR2) 抑制剂，具有抗肿瘤活性，抑制 ALR1 受体。
T62456	ALR1/2-IN-1
	ALR1/2-IN-1 (Compound 6e) 是一种醛还原酶 (ALR1) (IC50: 3.26 μM) 和醛糖还原酶 (ALR2) (IC50: 3.06 μM) 抑制剂，具有抗癌作用。
T60601	Aldose reductase-IN-4
	Aldose reductase-IN-4 (comund IIc) 是一种醛糖还原酶的抑制剂，其对ALR1和ALR2的IC50值分别为 11.70 μM 和 0.98 μM。
T60897	Aldose reductase-IN-5
	Aldose reductase-IN-5 是一种醛糖还原酶（ALR2）抑制剂，可增强抑制性兴奋性和抗氧化能力的组合，从而延缓糖尿病并发症的进程。

化合物

ALR2-IN-1

Cat.No: T77523

Synonym:

Target: Reductase

Target: Reductase

2-Chloro-1-(4-fluorobenzyl)benzimidazole

Cat.No: T7478

Synonym:

Target: Reductase

IDD388

Cat.No: T27583

Synonym: IDD-388,IDD 388

Target: DNA/RNA Synthesis

Aldose reductase-IN-4

Cat.No: T60601

Synonym:

Target:

Aldose reductase-IN-5

Cat.No: T60897

Synonym:

Target:

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02438	AKR1B1 Protein, Human, Recombinant (His) ALDR1,AR,ADR,aldo-keto reductase family 1, member B1 (aldose...	Human	E. coli
	Aldose reductase (AKR1B1) belongs to the aldo/keto reductase superfamily. AKR1B1 is a NADPH-dependent aldo-keto reductase best known as the rate-limiting enzyme of the polyol pathway. Expression of AKR1B1 was the highest in lens and retina. It is the first enzyme in the polyol pathway through which glucose is converted to sorbitol which is important for the function of various organs in the body, and has been implicated in the etiology of diabetic complications. AKR1B1 is quite abundant in the c...
TMPH-03065	Alr2278 Protein, Nostoc sp., Recombinant (His & MBP)	Nostoc	Baculovirus Insect Cells
	Alr2278 Protein, Nostoc sp., Recombinant (His & MBP) is expressed in Baculovirus.