Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T22029 |
AL 34662
|
5-HT Receptor; Adrenergic Receptor | GPCR/G Protein; Neuroscience |
AL 34662 是一种具有选择性和高效性的 5-HT2A 受体激动剂,对大鼠和人 5-HT2 受体的IC50 分别为 0.77 nM 和 1.5 nM。AL 34662 还是一种亲和力较低的 α-1D 肾上腺素能激动剂,EC50 值为 0.4 μM。AL 34662 可用于降低眼压。 | |||
T69357 |
AL-34662
|
||
AL-34662 is a serotonin-2 receptor agonist with antihypertensive action. AL-34662 has a high-affinity for the 5-HT2 receptor and may potentially lead mobilization of [Ca2+]i in h-CM and h-TM cells leading to a decrease in ocular pressure. |