Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T26642 |
Aplaviroc hydrochloride
AK602,AK 602,GW873140A,GW-873140,GW873140,AK-602,Aplaviroc HCl |
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Aplaviroc is a human cellular CC chemokine receptor 5 (CCR5) entry inhibitor. Aplaviroc binds specifically to CCR5 and demonstrates potent anti-human immunodeficiency virus activity in vitro in the subnanomolar range. In vitro studies show that aplaviroc | |||
T14307 |
Aplaviroc
AK 602,GW 873140,GSK 873140 |
HIV Protease; CCR | Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome |
Aplaviroc (AK 602), a SDP derivative, is a CCR5 antagonist. With IC50s of 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL and HIV-1MOKW. |