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Cat. No. Product Name Target Signaling Pathways
T8408 GKT136901

AK120765

NADPH-oxidase; NADPH Immunology/Inflammation; Metabolism
GKT136901 (AK120765) 是选择性的和具有口服活性的 NADPH 氧化酶 NOX-1/4抑制剂,Ki 分别为 160 和 165 nM。它具有抗炎症活性。它也是一种选择性和直接的过氧亚硝酸清除剂。它可用于糖尿病肾病,中风和神经退行性疾病的研究。
T38646 GKT136901 hydrochloride

GKT136901 hydrochloride

GKT136901 hydrochloride is a powerful, selective, and orally active inhibitor of NADPH oxidase (NOX1/4). It exhibits K i values of 160 nM and 165 nM against NOX1 and NOX4, respectively. Additionally, GKT136901 hydrochloride demonstrates selectivity and direct scavenging ability towards peroxynitrite. This compound finds utility in studying diabetic nephropathy, stroke, neurodegeneration, and possesses anti-inflammatory properties.

化合物

GKT136901
Cat.No: T8408
Synonym: AK120765
Target: NADPH-oxidase, NADPH
GKT136901 hydrochloride
Cat.No: T38646
Synonym: GKT136901 hydrochloride
Target:
TargetMol Loading
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