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Search Results for " adamts-5 "

Targets Recommended: Others

5

抑制剂 & 化合物

10

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T14124	ADAMTS-5 Inhibitor	Others	Others
	ADAMTS-5 Inhibitor 是 ADAMTS-5 的抑制剂，IC50 为 1.1 µM，可用于关节炎中软骨破坏的研究。
T72868	ADAMTS-5-IN-2
	ADAMTS-5-IN-2 是一种有效的ADAMTS-5抑制剂，IC50值为 0.71 µM。ADAMTS-5-IN-2 具有改善骨关节炎的研究潜力。
T62282	ADAMTS-5-IN-3
	ADAMTS-5-IN-3 (Example 37-2) 是一种有效的 ADAMTS-5 (IC50: 8 nM)和 ADAMTS-4 (IC50: 12 nM) 抑制剂。ADAMTS-5-IN-3 能够用于研究软骨退化或软骨稳态破坏相关疾病，尤其是骨关节病和/或类风湿性关节炎。
T35859	Aldumastat GLPG1972,S201086,G504572	Others	Others
	Aldumastat（GLPG1972）是一种具有高效性、特异性和口服活性的 ADAMTS-5抑制剂。Aldumastat 可用于研究膝骨关节炎。
T5416	T-5224	MMP	Proteases/Proteasome
	T-5224 是选择性的转录因子c-Fos/activator protein (AP)-1抑制剂，具有抗炎作用，能够特异性抑制 c-Fos/c-Jun 的 DNA 结合活性，但对其他转录因子的结合活性无影响。它抑制 IL-1β 诱导的 Mmp-3、Mmp-13、Adamts-5 转录上调。

化合物

ADAMTS-5 Inhibitor

Cat.No: T14124

Target: Others

ADAMTS-5-IN-2

Cat.No: T72868

ADAMTS-5-IN-3

Cat.No: T62282

Cat.No: T35859

Synonym: GLPG1972,S201086,G504572

Target: Others

Cat.No: T5416

Target: MMP

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02485	ADAMTS5 Protein, Mouse, Recombinant (His) Implantin,ADAMTS-5,ADAM-TS 5,ADMP...	Mouse	E. coli
	ADAMTS5 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 77.8 kDa and the accession number is Q9R001.
TMPH-00891	ADAMTSL5 Protein, Human, Recombinant (His & Myc) THSD6,ADAMTS-like protein 5,Thrombospondin...	Human	E. coli
	May play a role in modulation of fibrillin microfibrils in the extracellular matrix (ECM). ADAMTSL5 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 56.0 kDa and the accession number is Q6ZMM2.
TMPY-05308	CD45 Protein, Human, Recombinant (aa 1-529, His) GP180,B220,L-CA,protein tyrosine phosphatase, receptor type,...	Human	HEK293 Cells
	CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5.
TMPY-05387	SLAMF7 Protein, Human, Recombinant (hFc) SLAM family member 7,19A,SLAM7,CS1,CD319,CRACC	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPY-04318	GRIK2 Protein, Human, Recombinant (hFc) GLUR6,EAA4,MRT6,GLR6,glutamate receptor, ionotropic, kainate...	Human	HEK293 Cells
	GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar disorder (BPD). The gene coding for GRIK2 has been suggested as a candidate gene for autism based on its localization in the autism-specific region on chromosome 6q21 and the involvement of receptor protein in cognitive functions like learning and memory. GRIK2 belongs to the gl...
TMPY-05547	SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated CS1,SLAM7,CD319,SLAM family member 7,CRACC,19A	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPJ-00854	ETS1 Protein, Human, Recombinant (His) V-ets Erythroblastosis Virus E26 Oncogene Homolog 1 (Avian),...	Human	E. coli
	ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or repressors of numerous genes. They are involved in stem cell development, cell senescence and death, and tumorigenesis. ETS1 is a transcription factor, containing one ETS DNA-binding domain and one PNT (pointed) domain. it has been shown to interact with TTRAP, UBE2I and Death As...
TMPY-05498	SR-BI/SCARB1 Protein, Human, Recombinant (hFc) HDLQTL6,SR-BI,SRB1,CD36L1,CLA-1,CLA1,scavenger receptor clas...	Human	HEK293 Cells
	SR-BI/SCARB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q8WTV0-5.
TMPK-01357	SIRP alpha V5 Protein, Human, Recombinant (His & Avi) MFR,PTPNS1,P84,BIT,MYD-1,MYD1,SHPS-1,SIRPA,SIRP α,SIRP α V	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.
TMPK-01363	SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated SIRP alpha,MFR,PTPNS1,SIRP α V5,P84,SHPS-1,BIT,CD17...	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c...

重组蛋白

ADAMTS5 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02485

Species: Mouse

Expression System: E. coli

ADAMTSL5 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-00891

Species: Human

Expression System: E. coli

CD45 Protein, Human, Recombinant (aa 1-529, His)

Cat.No: TMPY-05308

Species: Human

Expression System: HEK293 Cells

SLAMF7 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05387

Species: Human

Expression System: HEK293 Cells

GRIK2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04318

Species: Human

Expression System: HEK293 Cells

SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated

Cat.No: TMPY-05547

Species: Human

Expression System: HEK293 Cells

ETS1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00854

Species: Human

Expression System: E. coli

SR-BI/SCARB1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05498

Species: Human

Expression System: HEK293 Cells

SIRP alpha V5 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-01357

Species: Human

Expression System: HEK293 Cells

SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01363

Species: Human

Expression System: HEK293 Cells

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