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Search Results for " acc2 "

Targets Recommended: Mitochondrial Metabolism Monocarboxylate transporter

12

抑制剂 & 化合物

1

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T1768	7ACC2	Mitochondrial Metabolism; Monocarboxylate transporter	Membrane transporter/Ion channel; Metabolism
	7ACC2 是单羧酸盐转运蛋白抑制剂，IC50为 11 nM。它还是线粒体丙酮酸转运的有效抑制剂，可抑制乳酸涌入，通过抑制乳酸通量来发挥抗癌作用。
T62418	hACC2-IN-1
	hACC2-IN-1 是一种乙酰辅酶 A 羧化酶 2 (ACC2) 的有效抑制剂，对 hACC2 的 IC50 值为 2.5 μM。hACC2-IN-1 具有潜力进行肥胖的研究。
T7163	PF-05175157	Acetyl-CoA Carboxylase	Metabolism
	PF 05175157 是一种广谱的乙酰辅酶 A 羧化酶 (ACC) 抑制剂，对 ACC1 (human)，ACC2 (human)， ACC1 (rat) 和 ACC2 (rat) 具有抑制作用，IC50分别为 27.0, 33.0, 23.5 和 50.4 nM。
T7184	Firsocostat ND-630,NDI-010976,GS-0976	Acetyl-CoA Carboxylase	Metabolism
	Firsocostat (GS-0976) 是有效的乙酰辅酶A 羧化酶 (ACC) 抑制剂，抑制人类 ACC1 和 ACC2 的IC50分别为2.1和6.1 nM。
T3622	CP-640186 hydrochloride CP 640186 HCl,盐酸CP-640186	Acetyl-CoA Carboxylase	Metabolism
	CP-640186 hydrochloride (CP 640186 HCl) 是膜渗透性的乙酰辅酶A 羧化酶（ACC）抑制剂，抑制大鼠肝脏ACC1和大鼠骨骼肌ACC2的IC50为53 nM 和61 nM。
T1889	CP-640186 CP 640186	Acetyl-CoA Carboxylase	Metabolism
	CP-640186 是一种有效的乙酰辅酶 A 羧化酶 (ACC)抑制剂，抑制大鼠肝脏 ACC1 和大鼠骨骼肌 ACC2 的 IC50分别为 53 nM 和 61 nM。
TQ0243	ND-646	Acetyl-CoA Carboxylase	Metabolism
	ND-646 是乙酰辅酶 A 羧化酶（ACC）抑制剂，对重组 hACC1 和 hACC2的IC50分别为 3.5 nM 和 4.1 nM。
T61341	A-908292
	A-908292 is a highly potent and selective inhibitor of acetyl-CoA carboxylase 2 (ACC2), displaying an impressive IC50 of 38 nM. This compound serves as a valuable tool in the investigation of fatty acid metabolism [1].
T12062	MK-4074	Others	Others
	MK-4074 is a liver-specific acetyl-CoA carboxylase ACC1 and ACC2 inhibitor(IC50 of 3 nM).
T40675	CP-610431
	CP-610431 is a reversible, ATP-uncompetitive inhibitor of acetyl-CoA carboxylase (ACC), exhibiting isozyme nonselectivity. It inhibits both ACC1 and ACC2 with IC50 values of approximately 50 nM. CP-610431 offers potential application in metabolic syndrome research.
T63961	ACC1/2-IN-1
	ACC1/2-IN-1 是 ACC1/2 的有效抑制剂，可作用于 ACC1 (IC50: 98.06 nM) 和 ACC2 (IC50: 29.43 nM)。ACC1/2-IN-1 可用于研究癌症。
T61978	ACC1/2-IN-2
	ACC1/2-IN-2 (compound PF-3) 是有效的 ACC1/2抑制剂，IC50分别为 22 和 48 nM。 ACC1/2-IN-2 显示出抗增殖活性，可用于癌症相关研究。

化合物

Cat.No: T1768

Target: Mitochondrial Metabolism, Monocarboxylate transporter

Cat.No: T62418

Cat.No: T7163

Target: Acetyl-CoA Carboxylase

Cat.No: T7184

Synonym: ND-630,NDI-010976,GS-0976

Target: Acetyl-CoA Carboxylase

CP-640186 hydrochloride

Cat.No: T3622

Synonym: CP 640186 HCl,盐酸CP-640186

Target: Acetyl-CoA Carboxylase

Cat.No: T1889

Synonym: CP 640186

Target: Acetyl-CoA Carboxylase

Cat.No: TQ0243

Target: Acetyl-CoA Carboxylase

Cat.No: T61341

Cat.No: T12062

Target: Others

Cat.No: T40675

Cat.No: T63961

Cat.No: T61978

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04936	BCL2A1 Protein, Human, Recombinant (His) BFL1,ACC1,ACC-2,GRS,ACC-...	Human	E. coli
	B-cell lymphoma 2-related protein A1 (BCL2A1) is a member of the BCL-2 family of anti-apoptotic proteins that confers resistance to treatment with anti-cancer drugs. Immunohistochemical expression of Wnt11 and BCL2A1 in complete moles and normal villi. Bcl2 family proteins control mitochondrial apoptosis and its members exert critical cell type and differentiation stage-specific functions, acting as barriers against autoimmunity or transformation. Anti-apoptotic Bcl2a1/Bfl1/A1 is frequently der...

重组蛋白

BCL2A1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04936

Species: Human

Expression System: E. coli

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