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Cat. No.	Product Name	Target	Signaling Pathways
T0455	Clozapine 氯氮平,HF 1854,LX 100-129	Dopamine Receptor; Adrenergic Receptor; AChR	GPCR/G Protein; Neuroscience
	Clozapine (HF 1854) 是一种三环二苯二氮卓类药物，属于非典型抗精神病药物。它结合几种类型的中枢神经系统受体，并显示出独特的药理学特征。它是一种血清素拮抗剂，与 5-HT 2A/2C 受体亚型具有强结合力。它还对几种多巴胺能受体表现出很强的亲和力，但对多巴胺 D2 受体仅表现出较弱的拮抗作用，这种受体通常被认为可调节精神抑制活性。
T69129	Clozapine HCl
	Clozapine HCl is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. Agranulocytosis is a ...