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Search Results for " 5'deoxyadenosine "

21

抑制剂 & 化合物

6

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T60020	5'-Fluoro-5'-deoxyadenosine 5'-Fluoro-5'-deoxy-adenosine	Others	Others
	5'-Fluoro-5'-deoxyadenosine (5'-Fluoro-5'-deoxy-adenosine) 常用作研究放线菌卡特链霉菌的工具。
T21017	5'-Amino-5'-deoxyadenosine 5' Amino 5' deoxyadenosine,5'Amino5'deoxyadenosine,Nsc 238990,NH2dAdo	Apoptosis; Adenosine Receptor	Apoptosis; GPCR/G Protein; Neuroscience
	5'-Amino-5'-deoxyadenosine (NH2dAdo) 是一种针对惰性淋巴系统恶性肿瘤的腺苷激酶抑制剂，具有抗肿瘤和抗癌作用。5'-Amino-5'-deoxyadenosine 的抗癌机制通过抑制 DNA 合成，诱导细胞凋亡 (apoptosis) 等来实现。
T36869	5'-chloro-5'-Deoxyadenosine (hydrate)
	5'-chloro-5'-Deoxyadenosine (hydrate) is a nucleoside analog used as a substrate in polyketide biosynthesis. S-(5'-adenosyl)-L-methionine can be converted to 5'-chloro-5'-deoxyadenosine in a reaction catalyzed by a SAM-dependent chlorinase. Through a 7-step route, 5'-chloro-5'-deoxyadenosine can be converted to chloroethylmalonyl-CoA, which has been shown to be involved in the biosynthesis of the anticancer agent salinosporamide A in the marine bacterium S. tropica.
T37106	2'-Deoxyadenosine-5'-triphosphate (sodium salt hydrate)
	2'-Deoxyadenosine-5'-triphosphate (dATP) is a purine nucleotide and derivative of the nucleic acid adenosine 5'-triphosphate .1dATP is a substrate for DNA polymerase in the synthesis of DNA.2It is a noncompetitive inhibitor of ribonucleotide reductases, which provides feedback inhibition during DNA synthesis.1dATP has commonly been used in DNA synthesis, sequencing, and labeling in research applications.3,4dATP accumulates in adenosine deaminase deficiency, a disorder characterized by mutations ...
T40696	2'-NH2-ATP 2'-NH2-ATP,2'-Amino-2'-deoxyadenosine-5'-triphosphate
	2'-NH2-ATP (2'-Amino-2'-deoxyadenosine-5'-triphosphate) is an adenosine derivative compound that acts as a weak competitive inhibitor of ATP with a K i value of 2.3 mM. It finds utility in nucleic acid labeling.
TNU1255	5’-Azido-5’-deoxyadenosine
	5'-Azido-5'-deoxyadenosine is a Nucleoside Derivative - 5'-Modified nucleoside; Azido-nucleoside.
TNU0881	4’,5’-Didehydro-5’-deoxyadenosine
	4',5'-Didehydro-5'-deoxyadenosine is a Nucleoside Derivative - 5'-Modified nucleoside.
TNU1119	N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite 是一种腺嘌呤核苷类似物，具有潜在的血管扩张活性和抗癌活性，可用于研究癌症。
TNU1535	5’-O-DMTr-N6-ethyl-2’-deoxyadenosine
	Nucleoside Derivatives - 6-Modified purine nucleosides, Protected nucleosides with NH2/OH open
TNU1124	5’-O-(4,4’-Dimethoxytrityl)-2’-deoxyadenosine
	5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyadenosine is a Nucleoside Derivative - Protected nucleoside with NH2/OH open.
TNU1536	5’-O-DMTr-N6-ethyl-2’-deoxyadenosine 3’-CED phosphoramidite
	5'-O-DMTr-N6-ethyl-2'-deoxyadenosine 3'-CED phosphoramidite is a Nucleoside Phosphoramidite.
T66118	N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine
	N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66118，CAS号为 64325-78-6。
TNU1125	5’-O-(4,4’-Dimethoxytrityl)-3’-O-levulinyl-2’-deoxyadenosine
	Nucleoside Derivatives - Protected nucleosides with NH2/OH open; 3’-Modifed nucleosides; Used for conjugation
TNU1136	3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine
	3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine is a Nucleoside Derivative - Protected nucleoside with NH2/OH group open.
TNU1085	N6-Benzoyl-2’-chloro-5’-O-(4,4’-dimethoxytrityl)-2’-deoxyadenosine
	Nucleoside Derivatives - Halo-nucleoside; 2’-Modified nucleoside, Protected nucleosides with NH2/OH open
TNU1026	7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine
	Nucleoside Derivatives - Fluoro-modified nucleosides, 7-Deaza-purine nucleosides
T35766	SAHO
	SAHO is a sulfoxide form of the methyl donor S-(5'-adenosyl)-L-methionine chloride and a substrate for radical SAM enzymes.1It is reductively cleaved to S-adenosylhomocysteine , 5'-deoxyadenosine , and 5'-thioadenosine sulfenic acid by the radical SAM enzymes NosL or NosN. 1.Mandalapu, D., Ji, X., and Zhang, Q.Reductive cleavage of sulfoxide and sulfone by two radical S-adenosyl-L-methionine enzymesBiochemistry58(1)36-39(2019)
T21018	Anisodine hydrobromide
	5'-Amino-5'-deoxyadenosine is an inhibitor of adenosine kinase.
T35767	SAHO2
	SAHO2is a sulfone form of the methyl donor S-(5'-adenosyl)-L-methionine chloride and is a substrate for radical SAM enzymes.1It is reductively cleaved to 5'-deoxyadenosine and 5'-thioadenosine sulfinic acid by the radical SAM enzymes NosL or NosN. 1.Mandalapu, D., Ji, X., and Zhang, Q.Reductive cleavage of sulfoxide and sulfone by two radical S-adenosyl-L-methionine enzymesBiochemistry58(1)36-39(2019)
T78516	NUC-7738	Others	Others
	NUC-7738为3'-脱氧腺苷(3'-dA)的5'-芳氧基氨基磷酸酯前药，其对一组血液癌细胞系表现出有效细胞毒活性，可用于癌症研究。
T83829	2'-Deoxy-1,N6-ethenoadenosine-5'-O-triphosphate sodium ε-dATP
	ε-dATP是一种具有荧光性的嘌呤核苷酸2’-脱氧腺苷-5’-O-三磷酸（dATP）衍生物。它能在50至150µM的浓度范围内诱导初级小鼠脾脏T细胞和B细胞在脂多糖(LPS)或刀豆蛋白A刺激下发生姊妹染色单体交换。ε-dATP已被用于研究乙烯氯诱导的突变过程中模糊碱基配对的情况。相关的ATP衍生物ε-ATP，在300 nm激发下显示415 nm的发射峰值。

化合物

5'-Fluoro-5'-deoxyadenosine

Cat.No: T60020

Synonym: 5'-Fluoro-5'-deoxy-adenosine

Target: Others

5'-Amino-5'-deoxyadenosine

Cat.No: T21017

Synonym: 5' Amino 5' deoxyadenosine,5'Amino5'deoxyadenosine,Nsc 238990,NH2dAdo

Target: Apoptosis, Adenosine Receptor

5'-chloro-5'-Deoxyadenosine (hydrate)

Cat.No: T36869

2'-Deoxyadenosine-5'-triphosphate (sodium salt hydrate)

Cat.No: T37106

Cat.No: T40696

Synonym: 2'-NH2-ATP,2'-Amino-2'-deoxyadenosine-5'-triphosphate

5’-Azido-5’-deoxyadenosine

Cat.No: TNU1255

4’,5’-Didehydro-5’-deoxyadenosine

Cat.No: TNU0881

N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite

Cat.No: TNU1119

Target: Nucleoside Antimetabolite/Analog

5’-O-DMTr-N6-ethyl-2’-deoxyadenosine

Cat.No: TNU1535

5’-O-(4,4’-Dimethoxytrityl)-2’-deoxyadenosine

Cat.No: TNU1124

5’-O-DMTr-N6-ethyl-2’-deoxyadenosine 3’-CED phosphoramidite

Cat.No: TNU1536

N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine

Cat.No: T66118

5’-O-(4,4’-Dimethoxytrityl)-3’-O-levulinyl-2’-deoxyadenosine

Cat.No: TNU1125

3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine

Cat.No: TNU1136

N6-Benzoyl-2’-chloro-5’-O-(4,4’-dimethoxytrityl)-2’-deoxyadenosine

Cat.No: TNU1085

7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Cat.No: TNU1026

Cat.No: T35766

Anisodine hydrobromide

Cat.No: T21018

Cat.No: T35767

Cat.No: T78516

Target: Others

2'-Deoxy-1,N6-ethenoadenosine-5'-O-triphosphate sodium

Cat.No: T83829

Synonym: ε-dATP

Cat. No.	Product Name	Target	Signaling Pathways
T4971	5'-DEOXYADENOSINE 5′-dAdo,5-脱氧腺嘌呤核苷	Endogenous Metabolite	Metabolism
	5'-Deoxyadenosine (5′-dAdo) 是正常受试者尿液中发现的氧化核苷，氧化核苷代表了用于确定遗传物质损伤程度的生物标志物。
T40370	2′-Deoxyadenosine 5′-monophosphate disodium	Endogenous Metabolite	Metabolism
	2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide present in DNA. It is employed for researching adenosine-based interactions within DNA synthesis and damage analysis.
T4737	2'-Deoxyadenosine-5'-monophosphate D-AMP,2′-脱氧腺苷-5′-单磷酸,2'-Deoxyadenosine 5'-monophosphate,2'-脱氧腺苷-5'-单磷酸	Others; Endogenous Metabolite	Metabolism; Others
	2'-Deoxyadenosine-5'-monophosphate (D-AMP) 是一种存在于 DNA 中的脱氧核糖核苷酸，是一种核酸 AMP 衍生物。它能够用于研究 DNA 合成和 DNA 损伤过程中基于腺苷的相互作用。
T37635	2'-Deoxyadenosine-5'-triphosphate trisodium dATP trisodium	DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	2'-Deoxyadenosine-5'-triphosphate trisodium (dATP trisodium) 是一种核苷酸，是 DNA 聚合酶的底物，在细胞中用于 DNA 合成或复制。
T36667	2'-Deoxyadenosine-5'-triphosphate dATP,Deoxyadenosine 5-triphosphate	DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	2'-Deoxyadenosine-5'-triphosphate (Deoxyadenosine 5-triphosphate) (dATP) 是一种天然存在的小分子核苷酸，在细胞中用于DNA合成或复制。2'-Deoxyadenosine-5'-triphosphate (dATP) 是 DNA 聚合酶的底物。2'-Deoxyadenosine-5'-triphosphate 通过无活性的 α4beta4 四级结构抑制RNA。2'-Deoxyadenosine-5'-triphosphate 与心肌细胞生长有关。
T8227	5'-Methylthioadenosine Methylthioadenosine,5-脱氧-5-甲硫腺苷,5'-(Methylthio)-5'-deoxyadenosine,5'-Deoxy-5'-(methylthio)adenosine,5'-S-Methyl-5'-thioadenosine	Endogenous Metabolite	Metabolism
	5'-Methylthioadenosine (Methylthioadenosine) 是由 S-腺苷蛋氨酸在多胺合成过程中生成的核苷，通过抑制肿瘤细胞增殖、侵袭和诱导细胞凋亡来抑制肿瘤，同时控制肿瘤组织的炎症微环境。

天然产物

5'-DEOXYADENOSINE

Cat.No: T4971

Synonym: 5′-dAdo,5-脱氧腺嘌呤核苷

Target: Endogenous Metabolite

2′-Deoxyadenosine 5′-monophosphate disodium

Cat.No: T40370

Target: Endogenous Metabolite

2'-Deoxyadenosine-5'-monophosphate

Cat.No: T4737

Synonym: D-AMP,2′-脱氧腺苷-5′-单磷酸,2'-Deoxyadenosine 5'-monophosphate,2'-脱氧腺苷-5'-单磷酸

Target: Others, Endogenous Metabolite

2'-Deoxyadenosine-5'-triphosphate trisodium

Cat.No: T37635

Synonym: dATP trisodium

Target: DNA/RNA Synthesis, Endogenous Metabolite

2'-Deoxyadenosine-5'-triphosphate

Cat.No: T36667

Synonym: dATP,Deoxyadenosine 5-triphosphate

Target: DNA/RNA Synthesis, Endogenous Metabolite

5'-Methylthioadenosine

Cat.No: T8227

Synonym: Methylthioadenosine,5-脱氧-5-甲硫腺苷,5'-(Methylthio)-5'-deoxyadenosine,5'-Deoxy-5'-(methylthio)adenosine,5'-S-Methyl-5'-thioadenosine

Target: Endogenous Metabolite

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