搜索结果

Search Results for " 5'-gmp "

抑制剂 & 化合物

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T36983	Cyclic-di-GMP disodium Cyclic diguanylate,5GP-5GP disodium,3',5'-Cyclic diguanylic acid,Cyclic di-GMP (sodium salt),cyclic diguanylate disodium,c-di-GMP,c-di-GMP disodium	STING; Endogenous Metabolite	Immunology/Inflammation; Metabolism
	Cyclic-di-GMP disodium (5GP-5GP disodium) 是细菌的第二信使，也是一种 STING 激动剂，参与原核生物的多种过程，包括生物膜的形成、运动、和细胞周期的进展。Cyclic-di-GMP disodium 对癌细胞显示出抗增殖活性，可诱导 CD4 受体表达升高和细胞周期停滞。Cyclic-di-GMP disodium 可用于癌研究癌症。
T38122	5'-pGpG (sodium salt)
	5'-pGpG is a linearized form of cyclic di-GMP, a bacterial second messenger that activates the host innate immune system through stimulator of interferon genes (STING).1,2,3It is a metabolite of cyclic di-GMP formedviahydrolysis by various phosphodiesterases (PDEs) that binds to the cyclic di-GMP-I riboswitch with reduced affinity compared to cyclic di-GMP.4,55'-pGpG is intended for use as a negative control for cyclic di-GMP signaling.
T16677	Psicofuranine	Others	Others
	Psicofuranine also specifically inhibits GMP synthase and interrupts parasite growth. Psicofuramine is a nucleoside antibiotic. It has the inhibition of xanthosine 5'-phosphate aminase. Psicofuranine shows dose-dependent inhibition of P. falciparum growth
T73609	Ribonuclease T1
	Ribonuclease T1 (Rnase T1)，常用于生化研究。Ribonuclease T1 是一种内切酶，可特异性降解单链 RNA。Ribonuclease T1 能够形成核苷 2′，3′-环磷酸中间体，以切割 3′-鸟苷残基与邻近核苷 5′-OH 基团之间的磷酸二酯键，产生 3′-GMP 末端寡核苷酸。
T35422	5'-pApA (sodium salt)
	5'-pApA is a linearized form of cyclic di-AMP, a bacterial second messenger that activates the host innate immune system through stimulator of interferon genes (STING).1,2,3,4It is a metabolite of cyclic di-AMP formedviahydrolysis by various phosphodiesterases (PDEs).55'-pApA is intended for use as a negative control for cyclic di-AMP signaling. 1.Burdette, D.L., Monroe, K.M., Sotelo-Troha, K., et al.STING is a direct innate immune sensor of cyclic-di-GMPNature478(7370)515-518(2011) 2.Parvatiyar...

化合物

Cyclic-di-GMP disodium

Cat.No: T36983

Synonym: Cyclic diguanylate,5GP-5GP disodium,3',5'-Cyclic diguanylic acid,Cyclic di-GMP (sodium salt),cyclic diguanylate disodium,c-di-GMP,c-di-GMP disodium

Target: STING, Endogenous Metabolite

5'-pGpG (sodium salt)

5'-pApA (sodium salt)

Cat.No: T35422

Synonym:

Target:

Cat. No.	Product Name	Target	Signaling Pathways
T4901	5'-Guanylic acid disodium salt Guanosine 5'-monophosphate disodium salt,5'-鸟苷酸二钠,鸟苷钠5'-单磷酸,GMP-5	Others; Endogenous Metabolite	Metabolism; Others
	5'-Guanylic acid disodium salt (GMP-5) 由鸟嘌呤，核糖和磷酸组成，是信使 RNA 中的一种核苷酸单体。鸟苷衍生物参与细胞内信号转导，并已鉴定存在于端粒，核糖体 DNA，免疫球蛋白重链转换区和原癌基因的控制区中的重复基因组序列中。
T5065	GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD Monosodium-GMP,cGMP sodium salt,鸟苷-3',5'-环磷酸一钠盐,Cyclic GMP	PKA	Tyrosine Kinase/Adaptors
	GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD (cGMP sodium salt) 也称为 cGMP，是一种细胞调节剂，被描述为第二信使。它的水平随着各种激素的增加而增加，包括乙酰胆碱、胰岛素和催产素。 cGMP 激活蛋白激酶 G(PKG) 并调节离子通道电导，信号传导影响多种过程，包括平滑肌松弛和增殖、光转导和能量稳态。
T19346	5'-Guanylic acid 鸟苷酸,5'-guanosine monophosphate,5'-GMP	Endogenous Metabolite	Metabolism
	5'-Guanylic acid (5'-guanosine monophosphate) 与几种代谢紊乱有关，包括腺苷脱氨酶缺乏症、 aica-核糖体途径、腺嘌呤磷酸转移酶缺乏症 (aprt) 以及 2-羟基葡糖酸盐途径。