Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN1504 |
Citreorosein
羟基大黄素 |
cAMP; NF-κB; PI3K | GPCR/G Protein; NF-κB; PI3K/Akt/mTOR signaling |
Citreorosein is a cAMP phosphodiesterase inhibitor, it has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both MAPKs and AKT-mediated IκB kinase (IKK) phosphorylation and subsequent inhibition of transcription factor NF-κB activation. |