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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T69207 Chelerythrine hydroxide

Chelerythrine hydroxide is the salt form of Chelerythrine, a benzophenanthridine alkaloid present in the plant Chelidonium majus (greater celandine). It is a potent, selective, and cell-permeable protein kinase C inhibitor in vitro. And an efficacious antagonist of G-protein-coupled CB1 receptors.]This molecule also exhibits anticancer qualities and it has served as a base for many potential novel drugs against cancer.

化合物

Chelerythrine hydroxide
Cat.No: T69207
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T6S0052 Chelerythrine

Toddalin,Broussonpapyrine,白屈菜红碱,Cheleritrine

Apoptosis; BCL; PKC; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling
Chelerythrine (Broussonpapyrine) 是一种天然生物碱,为有效、选择性的 Ca2+/磷脂依赖性PKC 拮抗剂,IC50值为 0.7 μM。它具有抗肿瘤、抗糖尿病、抗炎的活性。它抑制BclXL-Bak BH3肽结合,IC50为 1.5 μM,并从 BclXL 取代了 Bax。它诱导细胞凋亡和自噬。
T3419 Chelerythrine chloride

白屈菜红碱,盐酸白屈菜红碱

Apoptosis; BCL; PKC; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling
Chelerythrine chloride 是一种可渗透细胞的蛋白激酶 C 抑制剂,对磷酸盐受体具有竞争性,而对 ATP 是非竞争性的。它诱导细胞凋亡和自噬。

天然产物

Chelerythrine
Cat.No: T6S0052
Synonym: Toddalin,Broussonpapyrine,白屈菜红碱,Cheleritrine
Target: Apoptosis, BCL, PKC, Autophagy
Chelerythrine chloride
Cat.No: T3419
Synonym: 白屈菜红碱,盐酸白屈菜红碱
Target: Apoptosis, BCL, PKC, Autophagy
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