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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T3627 IQ-1S free acid

IQ-1,IQ-1S,IQ-1S (free acid)

NF-κB; JNK MAPK; NF-κB
IQ-1S free acid (IQ-1S) 是 NF-κB/激活蛋白1 (AP-1) 抑制剂(IC50:2.3±0.41 μM)。它对 JNK1(Kd:240 nM)、JNK2(Kd:360 nM) 和 JNK3(Kd:100 nM)的都具有高的结合亲和力 。
T3635 IQ 1

IQ1,IQ-1

Wnt/beta-catenin Cytoskeletal Signaling; Stem Cells
IQ 1 有多种作用,如保持小鼠ESCs 的多功能性、降低Wnt 刺激的磷酸化、阻止PP2A/Nkd 的相互作用等等。
T4998L Cefpodoxime (free acid)

Others Others
Cefpodoxime (free acid) 是一种口服的第三代头孢菌素抗生素。除铜绿假单胞菌、肠球菌和脆弱拟杆菌外,它对大多数革兰氏阳性和革兰氏阴性微生物均有效。
T36370 4-Methylumbelliferyl-α-L-Iduronide (free acid)

4-Methylumbelliferyl-α-L-iduronide (free acid) is a fluorogenic substrate for α-L-iduronidase, an enzyme found in cell lysosomes that is involved in the degradation of glycosaminoglycans such as dermatan sulfate and heparin sulfate. 4-Methylumbelliferyl-α-L-iduronide is cleaved by α-L-iduronidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an...

化合物

IQ-1S free acid
Cat.No: T3627
Synonym: IQ-1,IQ-1S,IQ-1S (free acid)
Target: NF-κB, JNK
IQ 1
Cat.No: T3635
Synonym: IQ1,IQ-1
Target: Wnt/beta-catenin
Cefpodoxime (free acid)
Cat.No: T4998L
Synonym:
Target: Others
4-Methylumbelliferyl-α-L-Iduronide (free acid)
Cat.No: T36370
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T8504 Dianemycin

Nanchangmycin (free acid)

Antibacterial; Antibiotic Microbiology/Virology
Dianemycin (Nanchangmycin (free acid)) 由Streptomyces nanchangensis 产生的一种聚醚抗生素,抑制革兰氏阳性菌。它也是一种针对 Zika 病毒的广谱抗病毒药物。

天然产物

Dianemycin
Cat.No: T8504
Synonym: Nanchangmycin (free acid)
Target: Antibacterial, Antibiotic
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