Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T70083 |
Cilengitide hydrochloride
|
||
Cilengitide hydrochloride sis the salt form of Cilengitide, a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis. | |||
T6806 |
Cilengitide TFA
|
Integrin; Autophagy | Autophagy; Cytoskeletal Signaling |
Cilengitide TFA 是一种选择性的 αvβ3和 αvβ5受体整合素抑制剂,IC50分别为 4 nM 和 79 nM。对 GP IIb/IIIa 的选择性约为 10 倍。 | |||
T2494 |
Cilengitide
西仑吉肽,EMD 121974 |
Integrin; Autophagy | Autophagy; Cytoskeletal Signaling |
Cilengitide (EMD 121974) 是一种有效的 αvβ3/5 受体整合素抑制剂,可抑制 ανβ3和 ανβ5与玻连蛋白结合,IC50值分别为 4 和 79 nM。 |