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Cat. No. Product Name Target Signaling Pathways
T7766 Remdesivir

瑞德西韦,GS-5734

SARS-CoV; DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
Remdesivir (GS-5734) 是一种核苷类似物,一种广谱的抗病毒化合物,通过抑制病毒的 RNA 依赖性 RNA 聚合酶发挥活性。Remdesivir 对埃博拉病毒、SARS 病毒、MERS病毒等均有活性,对 COVID-19 有潜在治疗价值。
T74467 Remdesivir de(ethylbutyl 2-aminopropanoate)

Remdesivir de(ethylbutyl 2-aminopropanoate) 是 Remdesivir 的一种杂质,后者为一种具有抗病毒活性的核苷类似物。在 HAE 细胞针对 SARS-CoV 和 MERS-CoV 的实验中,Remdesivir 的 EC50 值为 74 nM;在针对鼠肝炎病毒的延迟脑肿瘤细胞实验中,其 EC50 值为 30 nM。此外,Remdesivir 亦被认为具有针对 2019-nCoV (COVID-19) 的研究潜力。
T69731 Remdesivir maleate

Remdesivir, also known as GS-5734, is a prodrug form of the antiviral nucleoside analog GS-44152. Remdesivir is a broad spectrum anti-viral drug that has shown to inhibit SARS-CoV-2, in vitro and in vivo. Efficacy of remdesivir against Ebola virus has been demonstrated. Remdesivir inhibits SARS-CoV-2 replication, reduces viral load, and exerts protective effects in SARS-CoV-2 infected animals. Remdesivir also reduces the pathological process, alleviates mild symptoms, and improves pulmonary les...
T12702 Remdesivir-D5

GS-5734-D5

Others Others
Remdesivir-D5 is a deuterium labeled Remdesivir. Remdesivir is a nucleoside analogue, with effective antiviral activity.

化合物

Remdesivir
Cat.No: T7766
Synonym: 瑞德西韦,GS-5734
Target: SARS-CoV, DNA/RNA Synthesis
Remdesivir de(ethylbutyl 2-aminopropanoate)
Cat.No: T74467
Synonym:
Target:
Remdesivir maleate
Cat.No: T69731
Synonym:
Target:
Remdesivir-D5
Cat.No: T12702
Synonym: GS-5734-D5
Target: Others
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