Cat. No. | Product Name | Target | Signaling Pathways |
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T7766 |
Remdesivir
瑞德西韦,GS-5734 |
SARS-CoV; DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Remdesivir (GS-5734) 是一种核苷类似物,一种广谱的抗病毒化合物,通过抑制病毒的 RNA 依赖性 RNA 聚合酶发挥活性。Remdesivir 对埃博拉病毒、SARS 病毒、MERS病毒等均有活性,对 COVID-19 有潜在治疗价值。 | |||
T74467 |
Remdesivir de(ethylbutyl 2-aminopropanoate)
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Remdesivir de(ethylbutyl 2-aminopropanoate) 是 Remdesivir 的一种杂质,后者为一种具有抗病毒活性的核苷类似物。在 HAE 细胞针对 SARS-CoV 和 MERS-CoV 的实验中,Remdesivir 的 EC50 值为 74 nM;在针对鼠肝炎病毒的延迟脑肿瘤细胞实验中,其 EC50 值为 30 nM。此外,Remdesivir 亦被认为具有针对 2019-nCoV (COVID-19) 的研究潜力。 | |||
T69731 |
Remdesivir maleate
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Remdesivir, also known as GS-5734, is a prodrug form of the antiviral nucleoside analog GS-44152. Remdesivir is a broad spectrum anti-viral drug that has shown to inhibit SARS-CoV-2, in vitro and in vivo. Efficacy of remdesivir against Ebola virus has been demonstrated. Remdesivir inhibits SARS-CoV-2 replication, reduces viral load, and exerts protective effects in SARS-CoV-2 infected animals. Remdesivir also reduces the pathological process, alleviates mild symptoms, and improves pulmonary les... | |||
T12702 |
Remdesivir-D5
GS-5734-D5 |
Others | Others |
Remdesivir-D5 is a deuterium labeled Remdesivir. Remdesivir is a nucleoside analogue, with effective antiviral activity. |