Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16122 |
MMAF sodium
Monomethylauristatin F sodium |
ABC | Membrane transporter/Ion channel |
MMAF sodium is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A. MMAF sodium is an effective tubulin polymerization inhibitor and is used as an antitumor agent. | |||
T16121 |
MMAF Hydrochloride
Monomethylauristatin F Hydrochloride |
Others | Others |
MMAF Hydrochloride is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A. MMAF Hydrochloride is an effective tubulin polymerization inhibitor and is used as an antitumor compound. | |||
T3256 |
MMAF
一甲基澳瑞他汀 F,MonoMethyl auristatin F |
Others; Microtubule Associated | Cytoskeletal Signaling; Others |
MMAF (MonoMethyl auristatin F) 是一种抗有丝分裂剂,通过阻断微管蛋白的聚合来抑制细胞分裂,用作抗肿瘤药物和抗体偶联药物的细胞毒性成分。 | |||
T10949 |
D8-MMAF
Monomethylauristatin F D8 |
Others | Others |
D8-MMAF is a microtubule destroyer, deuterated form of MMAF. |